UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F33H12.1	F33H12.1	1e-177	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	srh-8	K09D9.8	n/a	chrV 4,006,527	C. elegans SRH-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005394 (P2Y12 purinoceptor)
4	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
5	C02F5.3	C02F5.3	n/a	chrIII 8,246,494	contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF02824 (TGS domain) contains similarity to Interpro domains IPR005225 (Small GTP-binding protein), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR004095 (TGS), IPR006074 (GTP1/OBG, conserved site)
6	Y18D10A.9	Y18D10A.9	n/a	chrI 12,855,664	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
7	C07D8.2	C07D8.2	n/a	chrX 7,362,559	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
8	Y54E5B.2	Y54E5B.2	n/a	chrI 14,817,953	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
9	F16B12.5	F16B12.5	n/a	chrX 14,100,488	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
10	nhr-226	T27B7.3	n/a	chrV 2,295,897	C. elegans NHR-226 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR000083 (Fibronectin, type I), IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	clec-21	T07H3.4	n/a	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	Y41C4A.9	Y41C4A.9	n/a	chrIII 11,714,688	contains similarity to Pfam domain PF06862 Protein of unknown function (DUF1253) contains similarity to Interpro domain IPR010678 (Protein of unknown function DUF1253)
13	B0524.6	B0524.6	n/a	chrIII 1,903,905
14	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
15	alh-10	C54D1.4	n/a	chrX 7,142,025	C. elegans ALH-10 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
16	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
17	F38A1.6	F38A1.6	n/a	chrIV 1,252,165
18	F19C6.5	F19C6.5	n/a	chrX 9,983,681	contains similarity to Homo sapiens Isoform 2 of Zinc transporter 8; HI:HIT000389038
19	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	srh-270	F37B4.5	n/a	chrV 2,860,866	C. elegans SRH-270 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	F22H10.6	F22H10.6	n/a	chrX 16,690,126
22	tgt-1	ZK829.6	n/a	chrIV 11,958,629	tgt-1 encodes a tRNA-guanine transglycosylase predicted to be mitochondrial.
23	F29C12.6	F29C12.6	n/a	chrII 13,129,953	contains similarity to Helicobacter pylori Cytotoxicity associated immunodominant antigen (120 kDa protein)s(CAG pathogenicity island protein 26).; SW:CAGA_HELPY
24	F09D1.1	F09D1.1	n/a	chrII 2,570,590	contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02148 (Zn-finger in ubiquitin-hydrolases and other protein) contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR001607 (Zinc finger, UBP-type)
25	Y37E11B.6	Y37E11B.6	n/a	chrIV 3,598,943	Y37E11B.6 encodes an ortholog of Rpp21 (Rpr2), a protein subunit of the endoribonuclease RNAse P, which cleaves tRNA precursors to produce their mature 5' end.
26	C29F9.2	C29F9.2	n/a	chrIII 131,349	contains similarity to Homo sapiens Isoform 3 of MAP7 domain-containing protein 1; ENSEMBL:ENSP00000362241
27	C46H11.2	C46H11.2	n/a	chrI 5,051,289	contains similarity to Pfam domains PF00743 (Flavin-binding monooxygenase-like) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000960 (Flavin-containing monooxygenase FMO), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
28	tor-2	Y37A1B.13	n/a	chrIV 13,983,393	tor-2 encodes a AAA ATPase that, along with TOR-1 and OOC-5, comprise the three C. elegans orthologs of human torsinA, mutations in which are associated with torsion dystonia (OMIM:605204); overexpression of TOR-2 in nematodes with polyglutamine repeat-induced protein aggregates indicates that TOR-2 can suppress protein aggregation, suggesting TOR-2 may play a role in regulation of protein folding; in wild-type animals, TOR-2 localizes to the endoplasmic reticulum; in animals containing polyglutamine protein aggregates, TOR-2 localizes to these sites of protein aggregation.
29	F22H10.5	F22H10.5	n/a	chrX 16,687,280	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
30	VW02B12L.2	VW02B12L.2	n/a	chrII 11,439,443	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
31	cah-5	R173.1	n/a	chrX 7,021,932	cah-5 encodes a member of the carbonic anhydrase family.
32	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
33	srh-269	T03E6.5	n/a	chrV 16,591,043	C. elegans SRH-269 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	C14E2.1	C14E2.1	n/a	chrX 1,826,905
35	Y17G7B.12	Y17G7B.12	n/a	chrII 12,024,783	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
36	C53C11.1	C53C11.1	n/a	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
37	F40E3.6	F40E3.6	n/a	chrI 2,651,225
38	K06A9.3	K06A9.3	n/a	chrX 1,534,681	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site)
39	T22F3.10	T22F3.10	n/a	chrV 3,608,429	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	D1005.6	D1005.6	n/a	chrX 1,463,763
41	F52E1.9	F52E1.9	n/a	chrV 8,398,736	contains similarity to Interpro domain IPR011332 (Ribosomal protein, zinc-binding)
42	F52H2.5	F52H2.5	n/a	chrX 2,558,768
43	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
44	K10D2.4	K10D2.4	n/a	chrIII 5,173,569
45	C30F12.1	C30F12.1	n/a	chrI 6,957,790	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domain IPR000571 (Zinc finger, CCCH-type)
46	F35E8.2	F35E8.2	n/a	chrV 15,906,320	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DZ81
47	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
48	ugt-10	T19H12.11	n/a	chrV 4,899,135	C. elegans UGT-10 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
49	Y39A1A.22	Y39A1A.22	n/a	chrIII 10,705,056	contains similarity to Pfam domains PF03124 (EXS family) , PF03105 (SPX domain) contains similarity to Interpro domains IPR004342 (EXS, C-terminal), IPR004331 (SPX, N-terminal)
50	F53H1.1	F53H1.1	n/a	chrIV 1,303,451	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)