UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-102	F33E2.3	0	chrI 12,579,521	C. elegans CLEC-102 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
4	C09B8.4	C09B8.4	n/a	chrX 6,019,168	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
5	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
6	K10C2.6	K10C2.6	n/a	chrX 6,451,568
7	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
8	M151.2	M151.2	n/a	chrII 3,632,782	contains similarity to Interpro domain IPR000533 (Tropomyosin)
9	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
10	nhr-214	T07C5.3	n/a	chrX 12,701,293	C. elegans NHR-214 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	srg-8	T12A2.9	n/a	chrIII 6,254,139	C. elegans SRG-8 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
12	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
13	W03C9.5	W03C9.5	n/a	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
14	ZK1098.1	ZK1098.1	n/a	chrIII 9,523,635	ZK1098.1 encodes a protein, with multiple WW/rsp5/WWP domains and FF domains, required for embryonic viability and for normally high rates of postembryonic growth.
15	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
16	nhr-76	C05G6.1	n/a	chrIV 630,739	C. elegans NHR-76 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	Y54E2A.4	Y54E2A.4	n/a	chrII 14,754,890	contains similarity to Archaeoglobus fulgidus NADH oxidase (NOXA-3).; TR:O29847
18	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
19	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
20	T23C6.3	T23C6.3	n/a	chrX 17,137,111
21	C32B5.6	C32B5.6	n/a	chrII 969,468
22	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
23	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
24	K09D9.12	K09D9.12	n/a	chrV 4,003,740
25	C14C6.6	C14C6.6	n/a	chrV 546,947	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
26	mut-7	ZK1098.8	n/a	chrIII 9,540,593	mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference.
27	K06H6.5	K06H6.5	n/a	chrV 577,400	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
28	lgc-18	T01H10.7	n/a	chrX 12,126,727	C. elegans LGC-18 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
29	AH9.1	AH9.1	n/a	chrX 2,245,299	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
30	srt-63	T28A11.15	n/a	chrV 3,255,375	C. elegans SRT-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	M151.4	M151.4	n/a	chrII 3,625,534	contains similarity to Interpro domain IPR000533 (Tropomyosin)
32	daf-18	T07A9.6	n/a	chrIV 422,580	daf-18 encodes a lipid phosphatase homologous to the human PTEN tumor suppresor (OMIM:601728, mutated in Cowden disease and several cancers); DAF-18 negatively regulates insulin-like signaling mediated by DAF-2/IR and AGE-1/PI3K and thus plays a role in metabolism, development, and longevity; based on sequence and genetic analysis, DAF-18 is predicted to dephosphorylate AGE-1-generated PIP3 in order to limit activation of the downstream AKT-1 and AKT-2 kinases that negatively regulate DAF-16.
33	B0034.5	B0034.5	n/a	chrII 5,973,873	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
34	T11F9.12	T11F9.12	n/a	chrV 11,494,950	contains similarity to Interpro domain IPR011735 (Conserved hypothetical protein, HtrL)
35	F10E7.6	F10E7.6	n/a	chrII 7,113,277
36	ubxn-4	ZK353.8	n/a	chrIII 8,404,541	C. elegans UBXN-4 protein; contains similarity to Pfam domain PF00789 UBX domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001012 (UBX)
37	odr-7	T18D3.2	n/a	chrX 12,460,277	odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily that affects chemotaxis to some volatile odorants and the cell fate of the AWA olfactory neurons; ODR-7 is expressed in the AWA neurons; in specifying the identity of the AWA neurons, ODR-7 appears to lie upstream of odr-10, which encodes a seven transmembrane domain olfactory receptor that is required for the response to diacetyl, an odorant detected by the AWA neurons.
38	srz-90	C18D4.9	n/a	chrV 17,528,936	C. elegans SRZ-90 protein
39	M01G12.6	M01G12.6	n/a	chrI 12,120,129	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	D1044.6	D1044.6	n/a	chrIII 5,539,373	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
41	str-81	T26H2.6	n/a	chrV 19,226,172	C. elegans STR-81 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	T26E4.7	T26E4.7	n/a	chrV 15,794,497	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
43	F29D11.2	F29D11.2	n/a	chrI 7,637,136	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
44	F54D12.4	F54D12.4	n/a	chrII 1,368,200
45	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
46	ser-3	K02F2.6	n/a	chrI 6,821,820	ser-3 encodes a putative homolog of mammalian 5-HT4 metabotropic serotonin receptors; SER-3 is required for normal inhibition of movement by 5-HT, with ser-3 mutants being hyperactive and excessively curling their male tails (but this phenotype is reversed by exogenous 5-HT, with ser-3 mutants then becoming sluggish); SER-3 activity is required for normally high brood sizes and for embryonic development, and weakly required for pharyngeal pumping; SER-3 is expressed in pharynx, head and tail neurons, nerve ring, and intestine.
47	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
48	C06B3.2	C06B3.2	n/a	chrV 13,901,062	contains similarity to Pfam domain PF00350 Dynamin family contains similarity to Interpro domain IPR001401 (Dynamin, GTPase region)
49	T05C1.5	T05C1.5	n/a	chrII 4,490,625	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
50	sri-63	F39E9.3	n/a	chrII 3,288,198	C. elegans SRI-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)