UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	flp-13	F33D4.3	9.999999999999999e-87	chrIV 7,697,747	C. elegans FLP-13 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
2	dod-6	T20G5.7	n/a	chrIII 10,197,925	C. elegans DOD-6 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
3	ttr-28	R90.3	n/a	chrV 12,904,670	C. elegans TTR-28 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
4	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
5	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
6	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
7	M04G7.1	M04G7.1	n/a	chrIV 456,400	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000877 (Proteinase inhibitor I12, Bowman-Birk), IPR003582 (Metridin-like ShK toxin)
8	hen-1	C36B7.7	n/a	chrX 7,116,551	hen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.
9	glr-5	ZC196.7	n/a	chrV 8,718,671	glr-5 encodes a kainate (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-5 activity is required for normal brood sizes, especially at high temperatures; GLR-5 is expressed in neurons.
10	C15C7.4	C15C7.4	n/a	chrX 3,146,822
11	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
12	cal-4	T07G12.1	n/a	chrIV 10,528,321	cal-4 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-1, CAL-2, CAL-3 and CMD-1); as loss of cal-4 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-4 in C. elegans development and/or behavior is not yet known.
13	T02D1.6	T02D1.6	n/a	chrIV 17,410,914	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002232 (5-Hydroxytryptamine 6 receptor), IPR000276 (GPCR, rhodopsin-like)
14	H04M03.12	H04M03.12	n/a	chrIV 5,900,480
15	C07A12.2	C07A12.2	n/a	chrX 4,545,119
16	F08G2.5	F08G2.5	n/a	chrII 13,833,272	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
17	glb-3	C06H2.5	n/a	chrV 11,139,410	glb-3 encodes a globin with no obvious function in mass RNAi assays.
18	mec-9	C50H2.3	n/a	chrV 9,911,331	mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons.
19	T27A10.2	T27A10.2	n/a	chrX 3,586,399
20	R07C12.1	R07C12.1	n/a	chrIV 4,153,281
21	C49G7.6	C49G7.6	n/a	chrV 4,041,399
22	F41D3.8	F41D3.8	n/a	chrI 12,267,803	contains similarity to Pfam domain PF01697 (Domain of unknown function)
23	F58B4.4	F58B4.4	n/a	chrV 10,931,009	contains similarity to Plasmodium yoelii Rhoptry protein.; TR:Q26216
24	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
25	F20A1.10	F20A1.10	n/a	chrV 7,052,940
26	nlp-11	ZK1320.10	n/a	chrII 9,690,787	C. elegans NLP-11 protein ;
27	T02E9.1	T02E9.1	n/a	chrV 11,351,210	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
28	flp-17	C52D10.11	n/a	chrIV 17,191,022	C. elegans FLP-17 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
29	sol-1	C15A11.3	n/a	chrI 7,392,485	C. elegans SOL-1 protein; contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
30	F07G11.7	F07G11.7	n/a	chrV 7,303,485	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
31	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
32	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
33	F28A12.3	F28A12.3	n/a	chrV 8,641,003
34	tig-2	F39G3.8	n/a	chrV 4,728,435	The tig-2 gene, like dbl-1, daf-7, and unc-129, encodes a TGF-beta-like protein.
35	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	R13D7.2	R13D7.2	n/a	chrV 7,410,557	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
37	nhr-6	C48D5.1	n/a	chrIII 3,576,162	nhr-6 encodes a nuclear receptor of the NR4A4 subfamily that is orthologous to the mammalian NGFI-B receptors and the Drosophila HR38 nuclear receptor (DHR38) that has been implicated in molting and metamorphosis; by homology, NHR-6 likely functions as a transcription factor that, based upon RNAi experiments, is required for normal ovulation and/or spermathecal development or function; an nhr-6 reporter fusion is expressed primarily in the anterior and posterior spermatheca during L3 and L4 larval stages, with some weak and variable expression also observed in two chemosensory neurons; nhr-6 mRNA is expressed in an oscillating manner throughout larval development, in a pattern that is slightly irregular with respect to the timing of larval molts and that exhibits consistently lower expression at the times when these molts actually occur.
38	F23D12.3	F23D12.3	n/a	chrX 14,442,916
39	C01G10.4	C01G10.4	n/a	chrV 15,089,864	contains similarity to Staphylococcus aureus Staphylococcal secretory antigen ssaA2 precursor.; SW:Q5HDQ9
40	nhr-120	C25B8.6	n/a	chrX 6,638,552	C. elegans NHR-120 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
42	W04A4.3	W04A4.3	n/a	chrI 13,680,877	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
43	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
44	cyp-14A5	F08F3.7	n/a	chrV 5,422,142	cyp-14A5 encodes a member of the cytochrome P450 family.
45	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
46	zig-4	C09C7.1	n/a	chrX 7,925,923	zig-4 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; ZIG-4 activity is required for maintenance of ventral nerve cord organization: the AVKL/R and PVQL/R axons of the left and right ventral nerve cords do not maintain their proper spatial positions and drift into the opposite cord; a zig-4::gfp reporter fusion is expressed in the PVT, ASK, BAG, and M2 neurons, with expression also seen during the L1 stage in pharyngeal mesoderm and ectoderm.
47	tag-329	C50F4.3	n/a	chrV 9,535,638	C. elegans TAG-329 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
48	F14D7.8	F14D7.8	n/a	chrV 14,312,353	contains similarity to Staphylococcus epidermidis Conserved hypothetical protein.; TR:Q8CSE5
49	M7.8	M7.8	n/a	chrIV 11,094,455	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
50	F55D10.4	F55D10.4	n/a	chrX 4,718,585