UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F32H5.1	F32H5.1	0	chrV 13,357,051	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
2	cut-4	E04D5.3	n/a	chrII 10,437,905	C. elegans CUT-4 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001507 (Endoglin/CD105 antigen)
3	F07C6.2	F07C6.2	n/a	chrIV 12,791,374	contains similarity to Amblyomma hebraeum 9.8 kDa basic protein.; TR:Q9GPM1
4	C06G8.1	C06G8.1	n/a	chrIV 10,779,821	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domains IPR004316 (MtN3 and saliva related transmembrane protein), IPR003091 (Voltage-dependent potassium channel)
5	C34B2.6	C34B2.6	n/a	chrI 10,679,640	contains similarity to Pfam domains PF00004 (ATPase family associated with various cellular activities (AAA)) , PF02190 (ATP-dependent protease La (LON) domain) , PF05362 (Lon protease (S16) C-terminal proteolytic domain) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR008268 (Peptidase S16, active site), IPR000767 (Disease resistance protein), IPR001270 (Chaperonin clpA/B), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR004815 (Peptidase S16, ATP-dependent protease La), IPR008269 (Peptidase S16, lon C-terminal), IPR003111 (Peptidase S16, lon N-terminal), IPR003593 (AAA+ ATPase, core), IPR001984 (Peptidase S16, Lon protease)
6	col-111	F29B9.9	n/a	chrIV 4,656,697	C. elegans COL-111 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
7	T06A1.5	T06A1.5	n/a	chrV 1,929,299	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
8	F13B12.2	F13B12.2	n/a	chrIV 10,427,657	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR001411 (Tetracycline resistance protein, TetB), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
9	arc-1	ZK1320.6	n/a	chrII 9,676,012	arc-1 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; arc-1 has a human homolog, MID1, which when mutated leads to Opitz syndrome (OMIM:300000).
10	ZC84.6	ZC84.6	n/a	chrIII 9,196,038	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
11	nhr-210	R11G11.12	n/a	chrV 518,366	C. elegans NHR-210 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	srz-64	Y57G7A.7	n/a	chrII 1,291,002	C. elegans SRZ-64 protein ;
13	C30H6.5	C30H6.5	n/a	chrIV 17,373,653	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN)
14	gst-42	D1053.1	n/a	chrX 11,727,007	gst-42 is orthologous to the human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known as MALEYLACETOACETATE ISOMERASE; GSTZ1; OMIM:603758), which when mutated is thought to lead to a variety of type I tyrosinemia.
15	srxa-2	F56D5.10	n/a	chrIV 9,423,882	C. elegans SRXA-2 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
16	col-152	F32G8.5	n/a	chrV 10,561,507	C. elegans COL-152 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
17	ZK1290.5	ZK1290.5	n/a	chrII 7,530,168	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
18	hmit-1.1	Y51A2D.4	n/a	chrV 18,520,286	hmit-1.1 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.1 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.1 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
19	F55A12.5	F55A12.5	n/a	chrI 5,347,791	contains similarity to Gallus gallus Nucleolin (Protein C23).; SW:P15771
20	fbxa-54	T12B5.2	n/a	chrIII 957,051	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
21	lact-8	Y42A5A.2	n/a	chrV 11,092,342	lact-8 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
22	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
23	C27A2.4	C27A2.4	n/a	chrII 5,058,455	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
24	C23H4.3	C23H4.3	n/a	chrX 12,227,955	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
25	pes-8	F18G5.2	n/a	chrX 9,254,218	pes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype.
26	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
27	K11G9.2	K11G9.2	n/a	chrV 6,675,280	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
28	D1054.1	D1054.1	n/a	chrV 10,769,166	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
29	F02D8.4	F02D8.4	n/a	chrV 14,986,177	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide)
30	nas-38	F57C12.1	n/a	chrX 560,901	C. elegans NAS-38 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00090 (Thrombospondin type 1 domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
31	H37A05.1	H37A05.1	n/a	chrV 13,652,199	H37A05.1 encodes a putative phosphatidic acid phosphatase orthologous to budding yeast PAH1 and human LPIN1 (OMIM:605518), LPIN2 (OMIM:605519, mutated in Majeed syndrome), and LPIN3 (OMIM:605520); H37A05.1 is expressed in vulval muscle; in mass RNAi assays, H37A05.1 is required for the osmotic integrity of eggs and for normal larval growth, body thickness, locomotion, and fertility; by orthology, H37A05.1 is expected to be dephosphorylated by SCPL-2.
32	K01D12.5	K01D12.5	n/a	chrV 12,398,255	contains similarity to Interpro domain IPR003980 (Histamine H3 receptor)
33	drr-1	F45H10.4	n/a	chrII 13,495,384	C. elegans DRR-1 protein; contains similarity to Interpro domain IPR008253 (Marvel)
34	C05D12.2	C05D12.2	n/a	chrII 11,420,763	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans)
35	C50F7.4	C50F7.4	n/a	chrIV 7,729,765	contains similarity to Pfam domains PF08442 (ATP-grasp domain) , PF00549 (CoA-ligase) contains similarity to Interpro domains IPR013650 (ATP-grasp fold, succinyl-CoA synthetase-type), IPR005811 (ATP-citrate lyase/succinyl-CoA ligase), IPR005809 (Succinyl-CoA synthetase, beta subunit), IPR013815 (ATP-grasp fold, subdomain 1), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR013816 (ATP-grasp fold, subdomain 2), IPR016102 (Succinyl-CoA synthetase-like)
36	grd-6	T18H9.1	n/a	chrV 9,223,090	grd-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-6 is expressed in hypodermis and in various neurons, in both head and tail, and the PVT interneuron; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-6 has no obvious function in RNAi assays.
37	rpt-5	F56H1.4	n/a	chrI 5,742,805	rpt-5 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-5 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
38	pqn-54	R09B5.5	n/a	chrV 1,465,672	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
39	C14C6.7	C14C6.7	n/a	chrV 549,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
40	R07E3.4	R07E3.4	n/a	chrX 10,331,226	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
41	F27D9.2	F27D9.2	n/a	chrX 7,674,579	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR000576 (Proton/sugar symporter, LacY), IPR016196 (MFS general substrate transporter)
42	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	alh-3	F36H1.6	n/a	chrIV 11,024,207	alh-3 encodes an aldehyde dehydrogenase predicted to be mitochondrial.
44	D1014.6	D1014.6	n/a	chrV 8,122,275	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
45	F35B3.4	F35B3.4	n/a	chrX 17,020,129	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
46	pxn-1	ZK994.3	n/a	chrV 8,498,505	C. elegans PXN-1 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) , PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (4), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
47	zig-6	T03G11.8	n/a	chrX 5,187,948	zig-6 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; loss of zig-6 activity in large-scale RNAi screens results in a Clear phenotype; a zig-6::gfp reporter fusion is expressed in anterior and posterior body wall muscle.
48	srt-22	ZK1037.3	n/a	chrV 15,315,273	C. elegans SRT-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	cnx-1	ZK632.6	n/a	chrIII 9,815,658	cnx-1 encodes the C. elegans ortholog of calnexin, a type I Ca2+-binding integral membrane protein of the endoplasmic reticulum (ER); CNX-1 binds calcium and is predicted to function as a molecular chaperone required for glycoprotein folding and maturation as well as regulation of intracellular calcium homeostasis; in C. elegans, cnx-1 activity is required at 25 degrees C for wild-type levels of fertility and normal embryonic and larval development; cnx-1 activity is also required for maintaining viability in response to ER stress; in addition, cnx-1(RNAi) can suppress necrotic-like cell death induced by hyperactivated MEC-4 and DEG-1 ion channels, suggesting that CNX-1 also plays a role in regulating necrotic cell death; CNX-1 expression is first detected ubiquitously in the early embryo, with expression then becoming restricted to embryonic head and tail regions; post-embryonic expression is seen in the excretory cell, head and tail neurons, spermatheca, intestine, germ cells, and spicules in the male tail; antibody staining of early embryos indicates that CNX-1 localizes to the endoplasmic reticulum; in regulating reproduction at 25 degrees C, cnx-1 functions redundantly with crt-1, which encodes calreticulin, an additional Ca2+-binding ER chaperone protein.
50	B0495.2	B0495.2	n/a	chrII 7,700,550	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)