UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cpz-1	F32B5.8	0	chrI 2,688,057	cpz-1 encodes a homolog of cathepsin z-like cysteine protease cyclically expressed in hypodermal cells throughout development (along with adult gonad and pharynx) and required for normal molting; CPZ-1 protein is present in cuticle regions shortly before their degradation during ecydsis, and this expression pattern is conserved in Onchocerca volvulus; cpz-1(ok497) and cpz-1(RNAi) worms have defective molting, along with misshapen heads and tails, defective gonads, and embryonic lethality.
2	kcc-1	R13A1.2	n/a	chrIV 7,215,841	C. elegans KCC-1 protein; contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR000076 (K-Cl co-transporter), IPR004841 (Amino acid permease-associated region), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
3	C23G10.6	C23G10.6	n/a	chrIII 6,193,307	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
4	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
5	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
6	pat-2	F54F2.1	n/a	chrIII 8,821,993	pat-2 encodes an alpha integrin subunit; during embryogenesis, pat-2 is essential for body wall muscle assembly and function and hence, proper elongation and hatching.
7	C10A4.1	C10A4.1	n/a	chrX 7,417,182	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
8	K10G9.1	K10G9.1	n/a	chrIII 10,296,799	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
9	ttr-12	F46B3.4	n/a	chrV 20,603,550	C. elegans TTR-12 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
10	T06G6.8	T06G6.8	n/a	chrI 12,725,522	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
11	str-146	F58G4.6	n/a	chrV 8,094,425	C. elegans STR-146 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	F48B9.2	F48B9.2	n/a	chrX 2,173,341
13	C14A4.13	C14A4.13	n/a	chrII 10,619,389	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	T14D7.1	T14D7.1	n/a	chrII 8,847,171	T14D7.1 is orthologous to the human gene ALANINE-GLYOXYLATE AMINOTRANSFERASE HOMOLOG (AGXT; OMIM:604285), which when mutated leads to disease.
15	F40F12.4	F40F12.4	n/a	chrIII 9,895,687	contains similarity to Interpro domain IPR000998 (MAM)
16	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
17	C55B7.3	C55B7.3	n/a	chrI 6,500,602	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
18	T15B12.2	T15B12.2	n/a	chrIII 5,300,917	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
19	W05B10.3	W05B10.3	n/a	chrV 12,661,622	contains similarity to Melanoplus sanguinipes entomopoxvirus ORF MSV209 putative vaccinia A21L homolog, similar to SW:P20996.; TR:Q9YVN3
20	tre-1	F57B10.7	n/a	chrI 6,556,662	C. elegans TRE-1 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR008928 (Six-hairpin glycosidase-like)
21	R10E8.3	R10E8.3	n/a	chrV 18,235,608	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
22	F13H8.8	F13H8.8	n/a	chrII 6,266,588	contains similarity to Drosophila hydei Axoneme-associated protein mst101(2).; SW:Q08696
23	Y38H6C.15	Y38H6C.15	n/a	chrV 20,530,900	contains similarity to Interpro domain IPR006017 (Caldesmon)
24	Y39A1A.14	Y39A1A.14	n/a	chrIII 10,649,949	contains similarity to Pfam domain PF03587 Nep1 ribosome biogenesis protein contains similarity to Interpro domain IPR005304 (Suppressor Mra1)
25	C07H6.3	C07H6.3	n/a	chrIII 7,511,662	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
26	F35E12.4	F35E12.4	n/a	chrV 13,732,426	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR003951 (Peptidase C58, Yersinia/Haemophilus virulence surface antigen), IPR003366 (CUB-like region)
27	clec-152	F10F2.6	n/a	chrIII 4,633,383	C. elegans CLEC-152 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	marc-6	F55A3.1	n/a	chrI 10,803,251	C. elegans MARC-6 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
29	Y41C4A.8	Y41C4A.8	n/a	chrIII 11,707,793	contains similarity to Aedes aegypti Hypothetical conserved protein (Putative uncharacterized protein).; TR:Q1HQM0
30	elo-7	F56H11.3	n/a	chrIV 9,530,584	The elo-7 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-7 has no known function in vivo.
31	clec-155	T04A8.3	n/a	chrIII 4,684,119	C. elegans CLEC-155 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	T20H9.6	T20H9.6	n/a	chrIII 2,247,987	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
33	C02D5.1	C02D5.1	n/a	chrIII 8,561,987	contains similarity to Pfam domains PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
34	C18E9.9	C18E9.9	n/a	chrII 8,988,878	contains similarity to Thermoplasma volcanium Hypothetical protein TV1312.; TR:Q978V3
35	srbc-44	ZC455.9	n/a	chrV 12,787,889	C. elegans SRBC-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
36	srx-78	C01G10.3	n/a	chrV 15,096,226	C. elegans SRX-78 protein
37	C34C12.4	C34C12.4	n/a	chrIII 3,468,832	contains similarity to Homo sapiens Uncharacterized protein C4orf34; ENSEMBL:ENSP00000295958
38	C55A6.7	C55A6.7	n/a	chrV 11,519,888	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
39	C50C3.2	C50C3.2	n/a	chrIII 8,185,577	contains similarity to Pfam domains PF00435 (Spectrin repeat) (4), PF00036 (EF hand) contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
40	Y54G9A.4	Y54G9A.4	n/a	chrII 13,714,353	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
41	F42G8.9	F42G8.9	n/a	chrIV 8,117,087
42	grd-2	F46B3.5	n/a	chrV 20,607,211	grd-2 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-2 is weakly required for normal molting; GRD-2 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
43	M02B1.4	M02B1.4	n/a	chrIV 12,824,564	contains similarity to Staphylococcus epidermidis Low temperature requirement B protein.; TR:Q8CMT2
44	col-110	F19C7.7	n/a	chrIV 4,608,935	C. elegans COL-110 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
45	nmr-2	T01C3.10	n/a	chrV 15,009,000	C. elegans NMR-2 protein ;
46	T10E9.3	T10E9.3	n/a	chrI 6,536,631	contains similarity to Pfam domain PF03351 DOMON domain contains similarity to Interpro domains IPR005018 (DOMON related), IPR013050 (DOMON)
47	aha-1	C25A1.11	n/a	chrI 10,195,452	aha-1 encodes an ortholog of human aryl-hydrocarbon receptor nuclear translocator; interacts with AHR-1 and HIF-1 in vitro, requires HIF-1 for proper localization, and is expressed ubiquitously.
48	daf-7	B0412.2	n/a	chrIII 812,789	daf-7 encodes a member of the transforming growth factor beta superfamily that affects dauer larvae formation in a TGF-beta-mediated pathway and also affects egg laying; expressed in the ASI neurons.
49	ZK354.8	ZK354.8	n/a	chrIV 5,305,065	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
50	C26B9.2	C26B9.2	n/a	chrX 5,341,141