UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F31D5.5	F31D5.5	0	chrII 4,199,547	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
2	pbo-4	K09C8.1	n/a	chrX 10,956,107	pbo-4 encodes a sodium/proton exchanger (also known as nhx-7), with a potential Ca[2+]/calmodulin binding domain in its C-terminal cytosolic region that could mediate calcium signaling; PBO-4 is expressed in the basolateral membrane of posterior intestinal cells; PBO-4 is required for normal posterior body muscle contraction (pBoc) during the defecation cycle; PBO-4 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton; specifically, PBO-4 may enable intercellular signals from intestinal cells (by secreting protons which then might activate PBO-5 in adjacent muscle cells).
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	his-68	T23D8.6	n/a	chrI 9,989,347	his-68 encodes an H2A histone.
5	M02F4.1	M02F4.1	n/a	chrX 3,028,999	contains similarity to Homo sapiens Isoform 1 of Splicing factor, arginine/serine-rich 12; ENSEMBL:ENSP00000284041
6	rcq-5	E03A3.2	n/a	chrIII 4,055,367	C. elegans RCQ-5 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004589 (DNA helicase, ATP-dependent, RecQ type), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
7	H11E01.2	H11E01.2	n/a	chrX 1,623,360	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
8	M02G9.3	M02G9.3	n/a	chrII 10,319,023	contains similarity to Pfam domain PF02363 Cysteine rich repeat contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR013032 (EGF-like region, conserved site)
9	F42A6.1	F42A6.1	n/a	chrIV 3,356,300
10	R11.3	R11.3	n/a	chrX 16,198,339	contains similarity to Haemophilus influenzae Hypothetical protein HI0386.; SW:YBGC_HAEIN
11	srd-43	R04D3.9	n/a	chrX 13,304,796	C. elegans SRD-43 protein ;
12	Y49G5B.1	Y49G5B.1	n/a	chrV 5,228,330	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
13	del-2	F58G6.6	n/a	chrIV 9,639,468	del-2 encodes an unfamiliar protein whose promoter drives expression in IL1, ASH, and OLQ.
14	ubc-12	R09B3.4	n/a	chrI 11,911,676	The ubc-12 gene encodes a ubiquitin-conjugating enzyme whose substrate is NED-8, and which is required for both embryogenesis and terminal hypodermal differentiation; ubc-12(RNAi) mutants either arrest during embryonic development or show pleotropic defects (e.g., vulval eversion during the L4 stage), as well as defective alae.
15	Y49F6C.7	Y49F6C.7	n/a	chrII 3,367,722
16	Y47H9C.9	Y47H9C.9	n/a	chrI 11,900,113	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
17	T26C5.4	T26C5.4	n/a	chrII 9,249,704	contains similarity to Encephalitozoon cuniculi SER/THR protein phosphatase 2-A (EC 3.1.3.16) (Serine/threoninesprotein phosphatase).; TR:Q8SS50
18	C23H5.1	C23H5.1	n/a	chrIV 2,132,010	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
19	K12H6.12	K12H6.12	n/a	chrII 2,810,497	contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
20	C15B12.6	C15B12.6	n/a	chrX 6,498,835
21	cyp-43A1	E03E2.1	n/a	chrX 5,716,005	C. elegans CYP-43A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
22	Y39A1A.17	Y39A1A.17	n/a	chrIII 10,688,996	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
23	clec-160	F09G8.8	n/a	chrIII 8,274,384	C. elegans CLEC-160 protein; contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
24	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
25	fbxa-37	ZC47.14	n/a	chrIII 1,286,023	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
26	F31D5.4	F31D5.4	2e-108	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
27	rrf-3	F10B5.7	n/a	chrII 8,165,532	rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3(allele) or rrf-3(allele2) mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene.
28	F47G9.4	F47G9.4	n/a	chrV 11,319,469	contains similarity to Pfam domain PF00643 B-box zinc finger contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
29	F36A2.2	F36A2.2	n/a	chrI 8,803,215	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
30	F22H10.4	F22H10.4	n/a	chrX 16,684,977
31	try-10	F15B9.5	n/a	chrV 13,011,526	C. elegans TRY-10 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
32	Y63D3A.4	Y63D3A.4	n/a	chrI 14,099,306	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR005637 (TAP, C-terminal), IPR009060 (UBA-like), IPR005135 (Endonuclease/exonuclease/phosphatase)
33	Y4C6B.6	Y4C6B.6	n/a	chrIV 5,347,749	The Y4C6B.6 gene encodes a homolog of the human gene GLCM, which when mutated leads to Gaucher disease type I (OMIM:230800).
34	srj-9	T20C4.1	n/a	chrV 3,432,956	C. elegans SRJ-9 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	sid-2	ZK520.2	n/a	chrIII 13,680,827	sid-2 encodes a novel, single-pass transmembrane protein; SID-2 is required for environmental-mediated (i.e. ingestion or soaking) RNA interference (RNAi); SID-2::GFP is expressed strongly in the intestine where it localizes to the apical (lumenal) membrane; SID-2::GFP is also expressed at much lower levels in the excretory duct cells; when expressed in Caenorhabditis briggsae, a related nematode species deficient for environmental RNAi, SID-2 is able to confer environmental RNAi.
36	F55A4.5	F55A4.5	n/a	chrX 1,031,456	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
37	F52C12.4	F52C12.4	n/a	chrIV 1,934,886	contains similarity to Pfam domains PF01535 (PPR repeat) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR012336 (Thioredoxin-like fold), IPR005113 (uDENN), IPR002885 (Pentatricopeptide repeat), IPR001194 (DENN)
38	clec-206	F59A7.1	n/a	chrV 2,002,373	C. elegans CLEC-206 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	W10G6.1	W10G6.1	n/a	chrX 16,245,293	contains similarity to Babesia bovis Merozoite surface antigen-2a2.; TR:Q95UH0
40	T26G10.3	T26G10.3	n/a	chrIII 9,413,048	contains similarity to Pfam domain PF01282 Ribosomal protein S24e contains similarity to Interpro domain IPR001976 (Ribosomal protein S24e)
41	dcs-1	Y113G7A.9	n/a	chrV 20,084,683	dcs-1 encodes a scavenger mRNA decapping enzyme; dcs-1 exhibits hydrolase activity in vitro, with specificity for 7meGMP in its primary nucleoside monophosphate binding site; dcs-1 is the upstream gene in an operon with fre-1, which encodes an NADPH-dependent flavin reductase; reporter fusions using dcs-1 upstream sequence direct expression throughout the life cycle in neurons and pharyngeal muscle; expression is present in dauer larvae and enhanced by heat shock.
42	fbxa-71	T20H9.3	n/a	chrIII 2,256,678	C. elegans FBXA-71 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
43	ZC116.1	ZC116.1	n/a	chrV 12,610,320	contains similarity to Interpro domain IPR001419 (HMW glutenin)
44	srw-83	ZK262.6	n/a	chrV 18,428,523	C. elegans SRW-83 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
45	C40A11.8	C40A11.8	n/a	chrII 2,150,922
46	K05G3.2	K05G3.2	n/a	chrX 16,497,319
47	pbo-6	F11C7.1	n/a	chrX 17,431,052	pbo-6/lgc-3 encodes a proton-gated ion channel which has no known function, but that is thought to form functional heterodimers with PBO-5/LGC-2; PBO-6 has no obvious non-nematode orthologs, but is paralogous to PBO-5; while heterologous PBO-6 has no activity when expressed in Xenopus oocytes, it produces strong currents when coexpressed with PBO-5 and stimulated by pH 6.0; PBO-6 is expressed in the most posterior bodywall muscles; unlike pbo-5 mutants, pbo-6(ok1564) mutants and pbo-6(RNAi) animals have no obvious phenotypes.
48	Y51H1A.2	Y51H1A.2	n/a	chrII 13,867,372	contains similarity to Pfam domain PF02759 RUN domain contains similarity to Interpro domain IPR004012 (RUN)
49	tag-179	T24D1.4	n/a	chrI 9,961,143	C. elegans TAG-179 protein; contains similarity to Pfam domain PF04922 DIE2/ALG10 family contains similarity to Interpro domains IPR016900 (Alpha-1, 2 glucosyltransferase Alg10), IPR007006 (DIE2/ALG10)
50	ceeh-1	K02F3.6	n/a	chrIII 830,425	ceeh-1 encodes a soluble epoxide hydrolase (sEH) orthologous to human ABHD7 and ABHD9; recombinant CEEH-1 is biochemically active in vitro on epoxyeicosatrienoic acids and leukotoxins (EpOMEs); conversely, CEEH-1 is inhibited by urea-based antagonists of mammalian sEH that elevate EpOME levels when fed to C. elegans; perhaps because of genetic redundancy with its paralog CEEH-2, CEEH-1 has no obvious function in mass RNAi assays.