UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	twk-12	F29F11.4	0	chrV 10,669,197	twk-12 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; as loss of TWK-12 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of TWK-12 in C. elegans development and/or behavior is not yet known; TWK-12 may, however, function redundantly with other TWK channels; the TWK-12 expression pattern has not been determined.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	ZC376.6	ZC376.6	n/a	chrV 14,188,934	contains similarity to Interpro domain IPR001028 (Glycoprotein phospholipase D)
5	F57B1.1	F57B1.1	n/a	chrV 13,194,570	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR006874 (Protein of unknown function DUF621)
6	F55G1.1	F55G1.1	n/a	chrIV 7,492,779
7	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
8	R08F11.7	R08F11.7	n/a	chrV 3,791,935	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
9	ZK1037.1	ZK1037.1	n/a	chrV 15,311,784	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
10	ZK721.3	ZK721.3	n/a	chrX 8,785,606
11	srw-113	ZK1037.9	n/a	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
12	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
13	W04B5.2	W04B5.2	n/a	chrIII 2,425,901	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR005386 (EDG-8 sphingosine 1-phosphate receptor)
14	Y59C2A.1	Y59C2A.1	n/a	chrII 2,210,488	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide), IPR000276 (GPCR, rhodopsin-like)
15	D2089.3	D2089.3	n/a	chrII 10,663,519	contains similarity to Homo sapiens hypothetical protein LOC150383; ENSEMBL:ENSP00000325301
16	F31A3.5	F31A3.5	n/a	chrX 17,558,148	contains similarity to Interpro domain IPR000694 (Proline-rich region)
17	srz-18	F46B3.11	n/a	chrV 20,622,846	C. elegans SRZ-18 protein; contains similarity to Interpro domain IPR001036 (Acriflavin resistance protein)
18	srd-74	C24H11.4	n/a	chrIII 11,782,974	C. elegans SRD-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	Y75B8A.11	Y75B8A.11	n/a	chrIII 12,188,150	contains similarity to Lymnaea stagnalis Neuropeptide Y precursor.; TR:Q9U0S9
20	C30G4.6	C30G4.6	n/a	chrX 17,077,020	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
21	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
22	C14E2.5	C14E2.5	n/a	chrX 1,824,473
23	T18D3.6	T18D3.6	n/a	chrX 12,450,290	contains similarity to Streptomyces coelicolor Chromosomal replication initiator protein dnaA.; SW:DNAA_STRCO
24	F54B11.8	F54B11.8	n/a	chrX 13,602,980	contains similarity to Silene gallica Reverse transcriptase (Fragment).; TR:Q8W3T3
25	F44A2.2	F44A2.2	n/a	chrV 9,319,570	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
26	srg-23	Y25C1A.11	n/a	chrII 3,095,026	C. elegans SRG-23 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
27	T16G12.4	T16G12.4	n/a	chrIII 10,058,154	contains similarity to Treponema denticola FlhB.; TR:Q9APY7
28	Y54G9A.1	Y54G9A.1	n/a	chrII 13,700,041	contains similarity to Carabus linnei NADH dehydrogenase subunit 5 (Fragment).; TR:O79584
29	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
30	T03G11.3	T03G11.3	n/a	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
31	srd-51	F15A2.3	n/a	chrX 13,483,631	C. elegans SRD-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
32	T05A6.5	T05A6.5	n/a	chrII 7,824,034	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
33	C08G5.6	C08G5.6	n/a	chrII 771,341
34	str-55	F26D2.7	n/a	chrV 16,416,377	C. elegans STR-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	F41E7.6	F41E7.6	n/a	chrX 10,308,733	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
36	C40H1.3	C40H1.3	n/a	chrIII 9,328,239	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000003630
37	B0244.6	B0244.6	n/a	chrIII 5,741,364	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
38	F16G10.14	F16G10.14	n/a	chrII 2,398,093	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
39	srt-14	ZC142.2	n/a	chrV 4,255,024	C. elegans SRT-14 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
40	C35C5.2	C35C5.2	n/a	chrX 11,539,654	contains similarity to Pfam domains PF04389 (Peptidase family M28) , PF02225 (PA domain) , PF04253 (Transferrin receptor-like dimerisation domain) contains similarity to Interpro domains IPR007365 (Transferrin receptor-like, dimerisation), IPR007484 (Peptidase M28), IPR003137 (Protease-associated PA)
41	T09F5.2	T09F5.2	n/a	chrV 15,151,275	contains similarity to Saccharomyces cerevisiae cell wall mannoprotein; SGD:YOR009W
42	C24A8.5	C24A8.5	n/a	chrX 4,328,634
43	clec-143	ZK673.9	n/a	chrII 10,469,224	C. elegans CLEC-143 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000158 (Cell division protein FtsZ, N-terminal), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
44	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
45	D1065.1	D1065.1	n/a	chrV 4,075,636	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
46	K09E3.1	K09E3.1	n/a	chrX 17,126,661
47	K07C11.10	K07C11.10	n/a	chrV 8,226,436	contains similarity to Homo sapiens hypothetical protein isoform 1; ENSEMBL:ENSP00000381337
48	str-141	F47G9.2	n/a	chrV 11,323,048	C. elegans STR-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	ZC317.2	ZC317.2	n/a	chrV 5,460,748
50	C01B10.9	C01B10.9	n/a	chrIV 6,633,581	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR017850 (Alkaline-phosphatase-like, core domain)