UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	aat-8	F28F9.4	0	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
2	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
3	fbxa-184	F45C12.8	n/a	chrII 1,710,841	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
4	ZK822.1	ZK822.1	n/a	chrIV 11,920,082	contains similarity to Homo sapiens myosin, heavy polypeptide 7B, cardiac muscle, beta; ENSEMBL:ENSP00000262873
5	mdt-4	ZK546.13	n/a	chrII 4,943,020	C. elegans MDT-4 protein ; contains similarity to Drosophila melanogaster Flybase gene name is MED4-PA;; FLYBASE:CG8609
6	cyb-2.1	Y43E12A.1	n/a	chrIV 10,986,675	C. elegans CYB-2.1 protein; contains similarity to Pfam domains PF00134 (Cyclin, N-terminal domain) , PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR004367 (Cyclin, C-terminal), IPR014400 (Cyclin, A/B/D/E)
7	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
8	F42A9.6	F42A9.6	n/a	chrIV 8,610,474
9	srh-187	F10G2.8	n/a	chrV 7,339,214	C. elegans SRH-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	srx-65	K07C6.8	n/a	chrV 3,922,434	C. elegans SRX-65 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
11	R11G1.2	R11G1.2	n/a	chrX 3,653,706
12	T10B11.4	T10B11.4	n/a	chrI 6,938,560
13	C07E3.9	C07E3.9	n/a	chrII 10,351,043	contains similarity to Pfam domain PF00068 Phospholipase A2 contains similarity to Interpro domains IPR016090 (Phospholipase A2), IPR001211 (Phospholipase A2, eukaryotic), IPR013090 (Phospholipase A2, active site)
14	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
15	C49D10.4	C49D10.4	n/a	chrII 3,871,448	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
16	C42D4.13	C42D4.13	n/a	chrIV 7,187,729	contains similarity to Interpro domain IPR004052 (Potassium channel, voltage dependent, Kv1.5)
17	C50H2.4	C50H2.4	n/a	chrV 9,917,432	contains similarity to Arabidopsis thaliana Putative cytochrome P450.; TR:Q9LQ26
18	F26D11.4	F26D11.4	n/a	chrV 7,947,903
19	T02G6.7	T02G6.7	n/a	chrI 11,828,074	contains similarity to Pfam domains PF00337 (Galactoside-binding lectin) , PF08277 (PAN-like domain) contains similarity to Interpro domains IPR006583 (CW), IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
20	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
21	W04A4.5	W04A4.5	n/a	chrI 13,669,210	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
22	C08A9.9	C08A9.9	n/a	chrX 17,107,104	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
23	C42C1.9	C42C1.9	n/a	chrIV 12,290,184	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
24	W05H12.2	W05H12.2	n/a	chrI 13,412,326	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
25	glr-7	C43H6.9	n/a	chrX 2,415,895	glr-7 encodes a protein containing a ligand-gated ion channel domain and is a predicted non-NMDA type ionotropic glutamate receptor; expressed in the pharyngeal nervous system.
26	sqv-3	R10E11.4	n/a	chrIII 9,779,478	sqv-3 encodes a beta(1,4)-galactosyltransferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos, vulval morphogenesis, and chondroitin synthesis; SQV-3 is orthologous to human human galactosyltransferase I (B4GALT7; OMIM:604327, mutated in the progeroid form of Ehlers-Danlos syndrome); sqv-3 transgenically rescues hamster cells lacking galactosyl transferase I; the common requirement for SQV-3 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
27	str-5	T23D5.12	n/a	chrV 15,753,810	C. elegans STR-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
28	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)
29	F53F4.12	F53F4.12	n/a	chrV 13,626,710	contains similarity to Plasmodium falciparum Histidine-rich protein.; SW:HRP3_PLAFS
30	C35D10.6	C35D10.6	n/a	chrIII 4,859,975	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
31	puf-12	ZK945.3	n/a	chrII 10,101,606	C. elegans PUF-12 protein; contains similarity to Pfam domain PF08144 CPL (NUC119) domain contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR012959 (CPL), IPR016024 (Armadillo-type fold)
32	F43C1.3	F43C1.3	n/a	chrIII 4,244,006	F43C1.3 encodes a protein containing an HIT-type zinc finger domain and a coiled-coil region; loss of F43C1.3 activity via RNAi results in slower than normal growth rates.
33	lgc-14	T01H10.2	n/a	chrX 12,112,417	C. elegans LGC-14 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
34	B0454.5	B0454.5	n/a	chrII 3,039,835	contains similarity to Homo sapiens 21 kDa protein; VG:OTTHUMP00000165983
35	C48B4.8	C48B4.8	n/a	chrIII 9,560,470	contains similarity to Bacillus subtilis Hypothetical protein ywcE precursor.; SW:YWCE_BACSU
36	flh-2	C26E6.2	n/a	chrIII 4,953,580	C. elegans FLH-2 protein; contains similarity to Pfam domain PF04500 FLYWCH zinc finger domain contains similarity to Interpro domain IPR007588 (Zinc finger, FLYWCH-type)
37	Y38A10A.6	Y38A10A.6	n/a	chrV 6,098,058	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) , PF04851 (Type III restriction enzyme, res subunit) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
38	mom-4	F52F12.3	n/a	chrI 9,898,245	mom-4 encodes a MAP kinase kinase kinase-related protein orthologous to Drosophila Tak1 and the vertebrate MAPKKK7 proteins; during embryonic development, mom-4 activity is required for positive regulation of the Wnt pathway signaling that governs anterior/posterior (A/P) polarity: MOM-4 stimulates the WRM-1/LIT-1-dependent phosphorylation of POP-1, a TCF/LEF-related transcription factor, leading to its downregulation in posterior daughters of A/P cell divisions.
39	W06A11.2	W06A11.2	n/a	chrII 4,060,321
40	T04A8.15	T04A8.15	n/a	chrIII 4,713,844	contains similarity to Saccharomyces cerevisiae Ubiquitin-specific protease; SGD:YDL122W
41	srv-22	H04M03.9	n/a	chrIV 5,879,196	C. elegans SRV-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
42	sra-9	AH6.14	n/a	chrII 9,533,057	C. elegans SRA-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
43	K03H1.11	K03H1.11	n/a	chrIII 9,951,334	contains similarity to Pfam domain PF00646 (F-box domain)
44	R05D3.1	R05D3.1	n/a	chrIII 8,384,526	contains similarity to Pfam domains PF00521 (DNA gyrase/topoisomerase IV, subunit A) , PF02518 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) , PF00204 (DNA gyrase B) contains similarity to Interpro domains IPR002205 (DNA topoisomerase, type IIA, subunit A or C-terminal), IPR013506 (DNA topoisomerase, type IIA, subunit B, region 2), IPR001241 (DNA topoisomerase, type IIA, subunit B or N-terminal), IPR011558 (DNA topoisomerase, type IIA, subunit B, conserved region), IPR013758 (DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta), IPR013757 (DNA topoisomerase, type IIA, subunit A, alpha-helical), IPR003594 (ATP-binding region, ATPase-like), IPR013759 (DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta), IPR001154 (DNA topoisomerase II, eukaryotic-type), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013760 (DNA topoisomerase, type IIA, central)
45	his-5	F45F2.3	n/a	chrV 8,535,370	his-5 encodes an H4 histone.
46	K05C4.4	K05C4.4	n/a	chrI 14,736,077	contains similarity to Homo sapiens Hypothetical protein KIAA1185; ENSEMBL:ENSP00000253061
47	T22C1.3	T22C1.3	n/a	chrI 7,939,331	contains similarity to Pfam domain PF06728 GPI transamidase subunit PIG-U contains similarity to Interpro domain IPR009600 (GPI transamidase subunit PIG-U)
48	ZC373.3	ZC373.3	n/a	chrX 10,061,060	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
49	C05C8.8	C05C8.8	n/a	chrV 7,253,723	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
50	T15D6.10	T15D6.10	n/a	chrI 12,395,188	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)