UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tag-173	F27D4.5	0	chrI 7,728,166	tag-173/F27D4.5 is orthologous to the human gene BRANCHED CHAIN KETO ACID DEHYDROGENASE E1, ALPHA POLYPEPTIDE (BCKDHB; OMIM:248600), which when mutated leads to maple syrup urine disease, type 1a; F27D4.5 protein is predicted to be mitochondrial.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
4	F57B10.9	F57B10.9	n/a	chrI 6,551,594	F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease.
5	ceh-40	F17A2.5	n/a	chrX 12,319,393	ceh-40 encodes one of two C. elegans homeodomain proteins homologous to Extradenticle (Exd/Pbx); ceh-40 genetically interacts with ceh-20 and unc-62 during embryonic development: while loss of ceh-40 activity alone results in no significant embryonic lethality, loss of ceh-40 and ceh-20, or ceh-40, ceh-20, and unc-62, results in incompletely penetrant embryonic lethality.
6	srw-133	T05B4.6	n/a	chrV 4,114,016	C. elegans SRW-133 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
7	F52H2.4	F52H2.4	n/a	chrX 2,546,392	contains similarity to Pfam domain PF00474 Sodium:solute symporter family contains similarity to Interpro domains IPR010979 (Ribosomal protein S13-like, H2TH), IPR001734 (Na+/solute symporter)
8	gcy-22	T03D8.5	n/a	chrV 20,818,085	gcy-22 is predicted to encode a guanylate cyclase.
9	C01B10.7	C01B10.7	n/a	chrIV 6,638,773	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
10	K01A12.2	K01A12.2	n/a	chrX 8,618,599
11	R74.6	R74.6	n/a	chrIII 4,203,243	contains similarity to Pfam domains PF03465 (eRF1 domain 3) , PF03464 (eRF1 domain 2) , PF03463 (eRF1 domain 1) contains similarity to Interpro domains IPR004405 (Probable translation factor pelota), IPR005140 (eRF1 domain 1), IPR005141 (eRF1 domain 2), IPR005142 (eRF1 domain 3)
12	srh-130	F14F9.1	n/a	chrV 5,152,066	C. elegans SRH-130 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
13	pqn-25	D1044.3	n/a	chrIII 5,510,853	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
14	F54H5.5	F54H5.5	n/a	chrII 6,625,330
15	sulp-1	C55B7.6	n/a	chrI 6,484,156	sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.
16	K09E3.1	K09E3.1	n/a	chrX 17,126,661
17	mog-4	C04H5.6	n/a	chrII 14,556,957	The mog-4 gene encodes a DEAH helicase orthologous to the Drosophila CG10689 and the S. cerevisiae PRP2 proteins.
18	R09H3.3	R09H3.3	n/a	chrX 1,667,620
19	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
20	C37A2.6	C37A2.6	n/a	chrI 6,788,535	contains similarity to Pfam domain PF06325 Ribosomal protein L11 methyltransferase (PrmA) contains similarity to Interpro domain IPR010456 (Ribosomal L11 methyltransferase)
21	ZK856.11	ZK856.11	n/a	chrV 10,204,273	contains similarity to Pfam domain PF01176 Translation initiation factor 1A / IF-1 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR006196 (S1, IF1 type), IPR001253 (Eukaryotic initiation factor 1A (eIF-1A))
22	clec-9	Y70C5C.2	n/a	chrV 16,705,835	C. elegans CLEC-9 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	B0348.2	B0348.2	n/a	chrV 46,173	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
24	mlt-4	ZC15.7	n/a	chrV 20,280,792	mlt-4 encodes a homolog of human INVS (inversin, OMIM:243305; mutated in nephronophthisis) that has no function in mass RNAi assays.
25	F37C4.3	F37C4.3	n/a	chrIV 3,883,226	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
26	C50F4.14	C50F4.14	n/a	chrV 9,548,707	The C50F4.14 gene encodes a putative GDP-fucose transporter orthologous to the human GDP-FUCOSE TRANSPORTER 1 gene (LAD II; OMIM:605881), which when mutated leads to congenital disorder of glycosylation, type IIc.
27	aco-1	ZK455.1	n/a	chrX 11,341,447	aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
28	AH9.1	AH9.1	n/a	chrX 2,245,299	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
29	T05A8.2	T05A8.2	n/a	chrII 2,710,658
30	T24A6.7	T24A6.7	n/a	chrV 3,525,734	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
31	nhr-185	F47C10.1	n/a	chrV 3,845,862	C. elegans NHR-185 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000306 (Zinc finger, FYVE-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	B0244.6	B0244.6	n/a	chrIII 5,741,364	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
33	F10D2.8	F10D2.8	n/a	chrV 7,150,438	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
34	T24E12.9	T24E12.9	n/a	chrII 3,766,771
35	gcy-19	C17F4.6	n/a	chrII 3,254,897	gcy-19 encodes a predicted transmembrane guanylyl cyclase; as loss of gcy-19 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-19 in C. elegans development and/or behavior is not yet known; by sequence similarity, however, GCY-19 can be predicted to function in chemosensory signal transduction.
36	Y56A3A.28	Y56A3A.28	n/a	chrIII 11,966,536	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
37	T26E4.7	T26E4.7	n/a	chrV 15,794,497	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
38	T05E8.3	T05E8.3	n/a	chrI 5,475,882	The T05E8.3 gene encodes a divergent DEAH helicase that is (apparently) unique to Caenorhabditis; it has no well-characterized orthologs in the complete Drosophila or S. cerevisiae genomes, and no obvious orthologs in the draft human genome sequence either.
39	ZK757.2	ZK757.2	n/a	chrIII 9,875,718	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
40	C15C7.1	C15C7.1	n/a	chrX 3,165,079	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR001388 (Synaptobrevin), IPR006012 (Syntaxin/epimorphin, conserved site)
41	ceh-20	F31E3.1	n/a	chrIII 6,980,772	ceh-20 encodes the C. elegans ortholog of the homeodomain co-factor Extradenticle (Exd/Pbx); together with ceh-40 and unc-62, ceh-20 activity is required for embryonic viability; ceh-20 is also required as a cofactor for LIN-39- and MAB-5- dependent postembryonic mesoderm patterning; in addition, ceh-20 is required for regulating post-embryonic migrations of the Q neuroblast descendants and for regulating vulval development; a CEH-20::GFP fusion protein is expressed in embryos and postembryonically in many cell types including the Q, P, and V cells and their descendants; CEH-20 localizes to the nucleus.
42	B0403.3	B0403.3	n/a	chrX 7,062,539
43	F09E5.10	F09E5.10	n/a	chrII 5,349,294	contains similarity to Interpro domain IPR009079 (Four-helical cytokine-like, core)
44	F28G4.4	F28G4.4	n/a	chrV 16,284,328	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR005069 (Protein of unknown function DUF271)
45	gcy-5	ZK970.6	n/a	chrII 10,313,230	gcy-5 encodes a predicted guanylate cyclase with strong similarity to rat atrial natriuretic peptide receptor A; expressed in ASER.
46	cdc-48.3	K04G2.3	n/a	chrI 8,034,273	C. elegans CDC-48.3 protein; contains similarity to Pfam domains PF07726 (ATPase family associated with various cellular activities (AAA)) , PF00004 (ATPase family associated with various cellular activities (AAA)) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR011703 (ATPase associated with various cellular activities, AAA-3), IPR003960 (AAA ATPase, conserved site), IPR003593 (AAA+ ATPase, core)
47	B0432.6	B0432.6	n/a	chrII 267,814	contains similarity to Interpro domain IPR000533 (Tropomyosin)
48	F28F8.7	F28F8.7	n/a	chrV 15,579,943	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domain IPR000949 (ELM2)
49	Y45F10D.2	Y45F10D.2	n/a	chrIV 13,774,081	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
50	C47F8.5	C47F8.5	n/a	chrI 12,322,989	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)