UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F26G1.6	F26G1.6	0	chrII 4,778,310	F26G1.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while F26G1.6 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
2	F15A8.7	F15A8.7	n/a	chrX 4,443,129	contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
3	acl-10	F55A11.5	n/a	chrV 11,775,146	C. elegans ACL-10 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
4	T05A10.4	T05A10.4	n/a	chrX 10,791,361	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001343 (Haemolysin-type calcium-binding region), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
5	T22C8.3	T22C8.3	n/a	chrII 8,621,191	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
6	T12E12.1	T12E12.1	n/a	chrIV 5,554,964	contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR002867 (Zinc finger, C6HC-type)
7	col-56	T08B2.2	n/a	chrI 6,233,530	C. elegans COL-56 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
8	R07A4.2	R07A4.2	n/a	chrX 10,745,349	contains similarity to Rhodopirellula baltica Probable serine/threonine-protein kinase pknB (EC 2.7.1.-).; TR:Q7UFE6
9	C32A3.2	C32A3.2	n/a	chrIII 3,629,439	contains similarity to Homo sapiens Kinesin-like protein KIF14; ENSEMBL:ENSP00000236917
10	T22G5.3	T22G5.3	n/a	chrV 13,882,397	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
11	H19J13.1	H19J13.1	n/a	chrX 12,268,942	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
12	ndx-3	Y38A8.1	n/a	chrII 4,954,109	The ndx-3 gene encodes a homolog of peroxisomal CoA diphosphatases in both S. cerevisiae (PCD1) and C. elegans (NDX-8); more generally, NDX-3 protein belongs to the family of NUDIX hydrolases.
13	AH10.4	AH10.4	n/a	chrV 14,137,472	contains similarity to Methanosarcina acetivorans Hypothetical protein MA1935.; TR:Q8TPH7
14	T05C1.3	T05C1.3	n/a	chrII 4,488,577
15	K10D3.4	K10D3.4	n/a	chrI 7,137,354	contains similarity to Pfam domains PF01683 (EB module) , PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
16	Y62H9A.7	Y62H9A.7	n/a	chrX 11,885,307	contains similarity to Mus musculus Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterases1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).; SW:CN1A_MOUSE
17	C05B5.4	C05B5.4	n/a	chrIII 9,994,892	contains similarity to Mus musculus Soluble guanylyl cyclase beta 2 subunit homolog.; TR:Q8BXH3
18	unc-50	T07A5.2	n/a	chrIII 10,316,260	unc-50 encodes an integral membrane protein orthologous to the Saccharomyces cerevisiae Golgi component Gmh1p; UNC-50 is required for regulating subtype-specific nicotinic receptor trafficking to the cell surface and thus, for normal synaptic transmission at the neuromuscular junction; UNC-50 is ubiquitously expressed from early embryogenesis to adulthood and localizes to the Golgi.
19	F15D3.9	F15D3.9	n/a	chrI 11,558,305
20	F20B4.2	F20B4.2	n/a	chrX 17,704,274
21	D1005.2	D1005.2	n/a	chrX 1,460,943	contains similarity to Pfam domain PF01704 UTP--glucose-1-phosphate uridylyltransferase contains similarity to Interpro domains IPR016267 (UTP--glucose-1-phosphate uridylyltransferase, subgroup), IPR002618 (UTP--glucose-1-phosphate uridylyltransferase)
22	F21G4.3	F21G4.3	n/a	chrX 9,896,105	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
23	ZK1225.1	ZK1225.1	n/a	chrI 13,206,699	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
24	pmp-3	C54G10.3	n/a	chrV 14,650,313	pmp-3 encodes a putative ABC transporter orthologous to human ABCD4 (OMIM:603214) and paralogous to PMP-5; pmp-3 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; PMP-3 has no obvious function in mass RNAi assays, and pmp-3(ok1087) mutants are at least grossly normal (in particular, they show no defects in the uptake stage of RNAi).
25	srh-40	Y40D12A.3	n/a	chrIII 6,611,482	C. elegans SRH-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	C33D3.4	C33D3.4	n/a	chrX 10,488,757	contains similarity to Buchnera aphidicola Exodeoxyribonuclease V beta chain (EC 3.1.11.5).; SW:EX5B_BUCAP
27	K02D3.2	K02D3.2	n/a	chrX 13,710,264	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
28	sre-52	C50E10.5	n/a	chrII 12,336,826	C. elegans SRE-52 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR005410 (Potassium channel, two pore-domain, THIK), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
29	npp-7	T19B4.2	n/a	chrI 5,694,480	C. elegans NPP-7 protein; contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
30	R07B1.3	R07B1.3	n/a	chrX 9,859,984	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
31	cnk-1	R01H10.8	n/a	chrIII 10,274,812	cnk-1 encodes a protein that contains a SAM domain, a PDZ domain, and a PH domain.
32	ZK688.3	ZK688.3	n/a	chrIII 7,894,068	contains similarity to Pfam domain PF01557 Fumarylacetoacetate (FAA) hydrolase family contains similarity to Interpro domains IPR010916 (TonB box, conserved site), IPR011234 (Fumarylacetoacetase, C-terminal-related), IPR002529 (Fumarylacetoacetase, C-terminal-like)
33	elpc-3	ZK863.3	n/a	chrV 12,180,438	C. elegans ELPC-3 protein; contains similarity to Pfam domains PF04055 (Radical SAM superfamily) , PF00583 (Acetyltransferase (GNAT) family) contains similarity to Interpro domains IPR007197 (Radical SAM), IPR006638 (Elongator protein 3/MiaB/NifB), IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase), IPR005910 (Histone acetyltransferase ELP3)
34	C31B8.1	C31B8.1	n/a	chrV 2,932,269
35	nhr-182	F41B5.9	n/a	chrV 2,258,611	C. elegans NHR-182 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	srh-72	ZC204.5	n/a	chrII 1,639,907	C. elegans SRH-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
38	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
39	clec-170	F38A1.1	n/a	chrIV 1,270,618	C. elegans CLEC-170 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
40	Y45F3A.5	Y45F3A.5	n/a	chrIII 10,585,998	contains similarity to Saccharomyces cerevisiae Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; SGD:YOR310C
41	cah-2	D1022.8	n/a	chrII 7,481,896	cah-2 encodes a predicted carbonic anhydrase.
42	F08B4.3	F08B4.3	n/a	chrIV 8,666,337	contains similarity to Interpro domain IPR000719 (Protein kinase, core)
43	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
44	sel-12	F35H12.3	n/a	chrX 917,054	sel-12 encodes a transmembrane domain protein orthologous to presenilins; during gonadal, germline, and vulval development, sel-12 functions, within receiving cells, to positively regulate lin-12 and glp-1 Notch-like signaling pathways; sel-12 presenilin activity and/or levels are likely regulated by the SET/NAP protein sub-family member encoded by spr-2, as mutations in sel-12 are suppressed by mutations in spr-2; spr-2 regulation of sel-12 occurs in a hop-1 presenilin dependent manner.
45	C29F7.6	C29F7.6	n/a	chrX 13,439,091	C29F7.6 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; C29F7.6 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); C29F7.6 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, C29F7.6 has no obvious function in mass RNAi assays.
46	F42A6.6	F42A6.6	n/a	chrIV 3,336,420	contains similarity to Pfam domain PF05603 Protein of unknown function (DUF775) contains similarity to Interpro domain IPR008493 (Protein of unknown function DUF775)
47	tbx-31	C36C9.2	n/a	chrX 1,672,652	tbx-31 encodes a diverged member of the T-box transcription factor family; by homology, TBX-31 is predicted to function as a transcriptional regulator during development, but as loss of tbx-31 activity via RNAi results in no obvious defects, the precise role of TBX-31 in C. elegans development and/or behavior is not yet known.
48	F55D12.2	F55D12.2	n/a	chrI 7,892,099	contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal)
49	srw-112	K12D9.9	n/a	chrV 3,005,101	C. elegans SRW-112 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
50	B0495.6	B0495.6	n/a	chrII 7,698,778	contains similarity to Pfam domain PF07189 Splicing factor 3B subunit 10 (SF3b10) contains similarity to Interpro domain IPR009846 (Splicing factor 3B subunit 5/RDS3 complex subunit 10)