UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F26D11.4	F26D11.4	3e-143	chrV 7,947,903
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	epac-1	T20G5.5	n/a	chrIII 10,191,417	C. elegans EPAC-1 protein; contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00027 (Cyclic nucleotide-binding domain) (2), PF00617 (RasGEF domain) , PF00618 (Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif) contains similarity to Interpro domains IPR008937 (Ras guanine nucleotide exchange factor), IPR011051 (Cupin, RmlC-type), IPR001895 (Guanine-nucleotide dissociation stimulator CDC25), IPR011991 (Winged helix repressor DNA-binding), IPR000595 (Cyclic nucleotide-binding), IPR002373 (cAMP/cGMP-dependent protein kinase), IPR014710 (RmlC-like jelly roll fold), IPR000651 (Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal), IPR000591 (Pleckstrin/ G-protein, interacting region)
4	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
5	C31E10.8	C31E10.8	n/a	chrX 14,007,275	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR011046 (WD40 repeat-like), IPR002011 (Receptor tyrosine kinase, class II, conserved site)
6	srt-34	F54E2.6	n/a	chrV 2,817,549	C. elegans SRT-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
7	T07D10.2	T07D10.2	n/a	chrI 12,622,116	T07D10.2 is orthologous to the human gene VASOPRESSIN RECEPTOR TYPE 2 (AVPR2; OMIM:304800), which when mutated leads to nephrogenic diabetes insipidus.
8	twk-36	R12G8.2	n/a	chrV 17,745,322	C. elegans TWK-36 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
9	T10B11.4	T10B11.4	n/a	chrI 6,938,560
10	F35C8.8	F35C8.8	n/a	chrX 5,373,263
11	T28F2.7	T28F2.7	n/a	chrI 3,658,340	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR001873 (Na+ channel, amiloride-sensitive)
12	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
13	gly-16	T15D6.2	n/a	chrI 12,380,173	gly-16 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-16 is expressed in the seam cells during embryonic stages.
14	W04A4.5	W04A4.5	n/a	chrI 13,669,210	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
15	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
16	ttr-40	E02C12.4	n/a	chrV 9,354,969	C. elegans TTR-40 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
17	F27D9.7	F27D9.7	n/a	chrX 7,667,592	contains similarity to Pfam domain PF01421 Reprolysin (M12B) family zinc metalloprotease contains similarity to Interpro domain IPR001590 (Peptidase M12B, ADAM/reprolysin)
18	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
20	srh-252	T19C9.3	n/a	chrV 17,222,863	C. elegans SRH-252 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000215 (Protease inhibitor I4, serpin)
21	acr-18	F28F8.1	n/a	chrV 15,555,125	acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 falls into the 'DEG-3' class of nAChR subunits, apparently unique to nematodes, which includes DEG-3, DES-2, ACR-5, ACR-17, ACR-20, and ACR-23.
22	sre-55	C50E10.7	n/a	chrII 12,330,123	C. elegans SRE-55 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
23	T10B11.5	T10B11.5	n/a	chrI 6,941,098	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
24	C31H5.1	C31H5.1	n/a	chrI 9,028,536	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative)
25	tax-4	ZC84.2	n/a	chrIII 9,183,509	tax-4 is orthologous to the human gene ROD PHOTORECEPTOR CGMP-GATED CHANNEL (CNGA1; OMIM:123825), which when mutated leads to disease.
26	srh-68	T21B4.5	n/a	chrII 12,507,810	C. elegans SRH-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002379 (ATPase, F0/V0 complex, subunit C)
27	K07E8.5	K07E8.5	n/a	chrII 652,962	K07E8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K07E8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
28	F27E5.5	F27E5.5	n/a	chrII 10,129,961	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
29	H10E21.4	H10E21.4	n/a	chrIII 18,471	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
30	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
31	str-73	F26D2.1	n/a	chrV 16,431,023	C. elegans STR-73 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	kin-29	F58H12.1	n/a	chrX 2,848,198	kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus.
33	aat-8	F28F9.4	n/a	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
34	T09F5.1	T09F5.1	n/a	chrV 15,149,875	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
35	ZC482.4	ZC482.4	n/a	chrIII 12,766,680	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
36	T27C4.2	T27C4.2	n/a	chrV 3,729,612
37	T11F9.1	T11F9.1	n/a	chrV 11,460,688	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	C36B7.1	C36B7.1	n/a	chrX 7,113,827	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	C17B7.5	C17B7.5	n/a	chrV 3,336,321	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domains IPR002345 (Lipocalin), IPR006588 (Protein of unknown function PAW)
40	T22H6.1	T22H6.1	n/a	chrX 12,768,557	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
41	str-135	F21F8.10	n/a	chrV 8,280,076	C. elegans STR-135 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	asm-1	B0252.2	n/a	chrII 6,911,299	asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages.
43	M02B7.5	M02B7.5	n/a	chrIV 3,813,489	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF01369 (Sec7 domain) contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR000904 (SEC7-like)
44	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
45	K03H1.8	K03H1.8	n/a	chrIII 9,945,970	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
46	ZK1055.4	ZK1055.4	n/a	chrV 6,586,468	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
47	col-70	H17B01.2	n/a	chrII 1,471,156	C. elegans COL-70 protein; contains similarity to Interpro domain IPR000694 (Proline-rich region)
48	C02G6.2	C02G6.2	n/a	chrV 5,873,482	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
49	lgc-45	W10G11.16	n/a	chrII 3,566,681	C. elegans LGC-45 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
50	srx-88	F43A11.1	n/a	chrV 11,584,291	C. elegans SRX-88 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR001991 (Sodium:dicarboxylate symporter)