UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	inx-4	F26D11.10	0	chrV 7,963,664	C. elegans INX-4 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
2	math-35	R52.3	n/a	chrII 2,105,696	C. elegans MATH-35 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
3	ckb-4	F22F7.5	n/a	chrV 2,107,900	ckb-4 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases.
4	F22B8.6	F22B8.6	n/a	chrV 16,101,647	F22B8.6 encodes a putative cystathionine gamma-lyase; F22B8.6 is orthologous to human CTH (OMIM:607657, mutated in cystathioninuria), extremely similar to its paralog ZK1127.10, and also paralogous to C12C8.2; either F22B8.6, or ZK1236.10, or both proteins weakly inhibit DHC-1 in vivo; otherwise, F22B8.6 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with ZK1127.10.
5	gly-19	F22D6.12	n/a	chrI 7,113,932	gly-19 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; it is probably coexpressed with gly-18 in the anal sphincter muscle.
6	C30G12.4	C30G12.4	n/a	chrII 7,262,590	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
7	C30G12.1	C30G12.1	n/a	chrII 7,300,470	contains similarity to Pfam domain PF06394 Pepsin inhibitor-3-like repeated domain contains similarity to Interpro domain IPR010480 (Proteinase inhibitor I33, aspin)
8	C05E11.7	C05E11.7	n/a	chrX 4,583,603
9	T03D3.5	T03D3.5	n/a	chrV 2,825,328
10	C46G7.2	C46G7.2	n/a	chrIV 6,016,483	contains similarity to Anisakis simplex 29kDa protein from Anisakis simplex.; TR:Q9U5Z9
11	glt-3	K08F4.4	n/a	chrIV 10,131,794	glt-3 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
12	math-19	C40D2.1	n/a	chrII 1,999,260	C. elegans MATH-19 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
13	eif-3.G	F22B5.2	n/a	chrII 8,443,436	eif-3.G encodes a homolog of eukaryotic translation initiation factor 3, subunit 4 that affects embryonic viability, fertility, and growth.
14	F08B12.1	F08B12.1	n/a	chrX 11,388,875	F08B12.1 is orthologous to the human gene AC133-2 ANTIGEN (PROML1; OMIM:604365), which when mutated leads to disease.
15	sulp-3	F41D9.5	n/a	chrX 8,405,893	sulp-3 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-3 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-3::GFP transcriptional fusion is expressed exclusively in the pharyngeal muscles.
16	W03G1.3	W03G1.3	n/a	chrIV 512,107
17	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
18	F55C10.4	F55C10.4	n/a	chrV 11,387,665	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
19	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
20	C35A5.5	C35A5.5	n/a	chrV 10,506,811	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
21	B0495.9	B0495.9	n/a	chrII 7,708,071
22	twk-26	C33D12.3	n/a	chrX 3,052,381	C. elegans TWK-26 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
23	F28C6.8	F28C6.8	n/a	chrII 8,607,222	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
24	gta-1	K04D7.3	n/a	chrIV 10,182,270	The gta-1 gene encodes an ortholog of the human gene GABAT, which when mutated leads to GABA-transaminase deficiency (OMIM:137150).
25	ckb-3	B0285.10	n/a	chrIII 4,371,823	ckb-3 encodes a putative choline kinase; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases.
26	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
27	srbc-45	ZC455.11	n/a	chrV 12,804,041	C. elegans SRBC-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
28	seld-1	Y45F10A.4	n/a	chrIV 13,507,532	C. elegans SELD-1 protein; contains similarity to Pfam domains PF02769 (AIR synthase related protein, C-terminal domain) , PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016188 (PurM, N-terminal-like), IPR000728 (AIR synthase related protein), IPR010918 (AIR synthase related protein, C-terminal), IPR004536 (Selenide water dikinase)
29	lgc-5	F17E9.7	n/a	chrIV 8,343,385	C. elegans LGC-5 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
30	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
31	C32D5.10	C32D5.10	n/a	chrII 6,350,550	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
32	pqn-38	F44B9.7	n/a	chrIII 8,026,555	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
33	glt-6	R05G6.6	n/a	chrIV 7,505,011	glt-6 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
34	F13B6.2	F13B6.2	n/a	chrIV 7,459,793
35	F42A10.5	F42A10.5	n/a	chrIII 6,172,231	contains similarity to Interpro domain IPR003072 (Orphan nuclear receptor, NOR1 type)
36	F23F12.8	F23F12.8	n/a	chrIII 6,485,986	F23F12.8 encodes a large (980-residue) protein, predicted to be secreted, with two chitin-binding peritrophin-A domains, separated by a low-complexity region; F23F12.8 is synthesized in larval and adult pharynx, a known site of chitin deposition; like CEJ-1 and CPG-2 in embryos, F23F12.8 might participate in chitin synthesis, and its peritrophin-A domains might enable mechanical cross-linking of chitin.
37	C04E12.12	C04E12.12	n/a	chrV 3,390,139	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
38	ZK593.1	ZK593.1	n/a	chrIV 10,911,466	contains similarity to Pfam domains PF02887 (Pyruvate kinase, alpha/beta domain) , PF00224 (Pyruvate kinase, barrel domain) contains similarity to Interpro domains IPR015806 (Pyruvate kinase, beta-barrel), IPR015794 (Pyruvate kinase, alpha/beta), IPR015795 (Pyruvate kinase, C-terminal-like), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core), IPR001697 (Pyruvate kinase), IPR015793 (Pyruvate kinase, barrel)
39	Y54E5A.6	Y54E5A.6	n/a	chrI 14,709,596	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00035 (Double-stranded RNA binding motif) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like), IPR000632 (Yeast Mrs6p protein), IPR001269 (Dihydrouridine synthase, DuS)
40	fce-1	C04F12.10	n/a	chrI 9,711,884	fce-1 encodes an ortholog of 'farnesylated-proteins converting enzyme 1' (FACE-1), and thus probably enables post-translational processing of proteins (such as LET-60/RAS) carrying a C-terminal CaaX motif; FCE-1 protein probably accounts for the EDTA-sensitive, tosylphenylalanylchloromethane-insensitive component of CaaX-proteolytic activity in membrane extracts from C. elegans, and FCE-1 can cleave a farnesylated peptide in vitro; the S. cerevisiae homolog of FCE-1 (Ste24p) cleaves the precursor of yeast a-factor mating pheromone after its farnesylated cysteine residue, and transgenic FCE-1 rescues a mating defect of mutant yeast lacking both the Ste24p and the Rce1p CaaX-proteases.
41	kin-3	B0205.7	n/a	chrI 10,735,304	kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
42	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
43	grl-29	T24A6.18	n/a	chrV 3,554,921	grl-29 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-29 is expressed in larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
44	F41B5.6	F41B5.6	n/a	chrV 2,240,376	contains similarity to Pfam domain PF03564 Protein of unknown function (DUF1759) contains similarity to Interpro domain IPR005312 (Protein of unknown function DUF1759)
45	nfyc-1	F23F1.1	n/a	chrII 44,432	C. elegans NFYC-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
46	T24F1.2	T24F1.2	n/a	chrII 11,304,196	contains similarity to Drosophila melanogaster Flybase gene name is CG7744-PA;; FLYBASE:CG7744
47	alr-1	R08B4.2	n/a	chrX 11,123,705	C. elegans ALR-1 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
48	K08D10.5	K08D10.5	n/a	chrIV 4,168,957	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
49	tor-1	Y37A1B.12	n/a	chrIV 13,985,958	C. elegans TOR-1 protein; contains similarity to Pfam domain PF06309 Torsin contains similarity to Interpro domains IPR017378 (Torsin, subgroup), IPR001270 (Chaperonin clpA/B), IPR000641 (CbxX/CfqX), IPR003593 (AAA+ ATPase, core), IPR010448 (Torsin)
50	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)