UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F25G6.1	F25G6.1	0	chrV 8,577,457
2	unc-120	D1081.2	n/a	chrI 8,461,612	unc-120 encodes a member of the MADS-box family of transcription factors that is most closely related to Drosophila blistered and the vertebrate serum response factors (SRFs); UNC-120 is required for locomotion and muscle development and for formation of the normal number of muscle A and I bands; UNC-120 is also required for maintaining wild-type expression levels of the muscle components actin and myosin; UNC-120 is first expressed in the early embryo in body wall muscle precursors and later is expressed in both body wall and vulval muscles.
3	math-39	T08E11.2	n/a	chrII 1,832,929	C. elegans MATH-39 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
4	W04G3.7	W04G3.7	n/a	chrX 11,084,822	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
5	srh-118	K03D7.6	n/a	chrV 17,495,205	C. elegans SRH-118 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	K09B11.3	K09B11.3	n/a	chrIV 13,430,380	contains similarity to Homo sapiens DJ614O4.3; ENSEMBL:ENSP00000305301
7	R05H10.5	R05H10.5	n/a	chrII 14,868,296	contains similarity to Pfam domain PF00255 Glutathione peroxidase contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000889 (Glutathione peroxidase)
8	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
9	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	tmbi-4	B0563.4	n/a	chrX 9,155,606	C. elegans TMBI-4 protein; contains similarity to Pfam domain PF01027 Uncharacterised protein family UPF0005 contains similarity to Interpro domain IPR006214 (Protein of unknown function UPF0005)
11	kqt-3	Y54G9A.3	n/a	chrII 13,704,530	kqt-3 encodes one of three C. elegans KCNQ-like potassium channel subunits and, with respect to humans, is most similar to the KCNQ1 channel protein which when mutated leads to inherited long QT syndrome (OMIM:607542); although loss of KQT-3 activity via large-scale RNAi screens results in no obvious abnormalities, KQT-3 likely functions to regulate cellular excitability as expression of KQT-3 in Xenopus oocytes can produce K+ channel currents that functionally resemble vertebrate M-currents; activity of these KQT-3 channels can be suppressed by coexpression with the human M1 muscarinic receptor and treatment with diacylglycerol analogs, although KQT-3 is less sensitive to each of these treatments than KQT-1; a KQT-3::GFP fusion protein is expressed in the anterior- and posterior-most intestinal cells, the anterior and posterior mechanosensory neurons ALM and PLM, amphid and phasmid neurons, and in some additional head neurons.
12	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
13	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
14	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
15	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
16	crb-1	F11C7.4	n/a	chrX 17,408,117	crb-1 encodes a homolog of Drosophila CRUMBS that affects dauer formation and feeding behavior; CRB-1 can bind cyclic AMP-response element (CRE) sites and be phosphorylated by PKA in vitro, and is expressed immediately apical to the zonula adherens in embryos and then ubiquitously later during development and in adults; CRB-1 is homologous to human CRB1 (OMIM:604210, mutated in retinitis pigmentosa 12 or Leber congenital amaurosis).
17	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
18	F52D1.2	F52D1.2	n/a	chrX 447,631
19	C01C4.2	C01C4.2	n/a	chrX 3,717,428
20	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
21	F23B2.3	F23B2.3	n/a	chrIV 9,134,019	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
22	C38D9.5	C38D9.5	n/a	chrV 17,589,380	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
23	ZK856.6	ZK856.6	n/a	chrV 10,199,178	contains similarity to Ralstonia solanacearum Composite TWO-component regulatory (Sensor kinase and responsesregulator hybrid) transcription regulator protein.; TR:Q8XWL8
24	F36D1.8	F36D1.8	n/a	chrI 11,257,879	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
25	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
26	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
27	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
28	srh-269	T03E6.5	n/a	chrV 16,591,043	C. elegans SRH-269 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	sru-47	F36D1.3	n/a	chrI 11,290,448	C. elegans SRU-47 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region), IPR003839 (Protein of unknown function DUF215)
30	F52C12.4	F52C12.4	n/a	chrIV 1,934,886	contains similarity to Pfam domains PF01535 (PPR repeat) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR012336 (Thioredoxin-like fold), IPR005113 (uDENN), IPR002885 (Pentatricopeptide repeat), IPR001194 (DENN)
31	sri-31	B0454.2	n/a	chrII 3,051,657	C. elegans SRI-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	K10H10.6	K10H10.6	n/a	chrII 14,504,011	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
33	Y6B3B.1	Y6B3B.1	n/a	chrI 13,699,504	contains similarity to Interpro domain IPR000533 (Tropomyosin)
34	pmp-3	C54G10.3	n/a	chrV 14,650,313	pmp-3 encodes a putative ABC transporter orthologous to human ABCD4 (OMIM:603214) and paralogous to PMP-5; pmp-3 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; PMP-3 has no obvious function in mass RNAi assays, and pmp-3(ok1087) mutants are at least grossly normal (in particular, they show no defects in the uptake stage of RNAi).
35	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
36	T03F7.6	T03F7.6	n/a	chrV 11,295,604	contains similarity to Interpro domain IPR001036 (Acriflavin resistance protein)
37	glb-2	C06E4.7	n/a	chrIV 7,262,720	glb-2 encodes a globin; glb-2 transcription is higher in L3 and dauers than in young adults; glb-2 has no obvious function in mass RNAi assays.
38	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
39	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
40	srx-16	T07H8.1	n/a	chrV 6,976,849	C. elegans SRX-16 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
41	cyp-13A12	F14F7.3	n/a	chrIII 13,026,202	C. elegans CYP-13A12 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
42	W09H1.3	W09H1.3	n/a	chrII 13,184,626	contains similarity to Homo sapiens cDNA FLJ31139 fis, clone IMR322001185; ENSEMBL:ENSP00000380962
43	M163.5	M163.5	n/a	chrX 14,475,017	contains similarity to Interpro domain IPR008995 ()
44	tag-236	R11B5.1	n/a	chrX 2,528,819	C. elegans TAG-236 protein; contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
45	str-20	C05E4.2	n/a	chrV 757,182	C. elegans STR-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	T07H6.4	T07H6.4	n/a	chrX 6,284,028	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR002396 (Selectin (CD62E/L/P antigen)), IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
47	his-68	T23D8.6	n/a	chrI 9,989,347	his-68 encodes an H2A histone.
48	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
49	srv-8	F53F1.7	n/a	chrV 13,419,959	C. elegans SRV-8 protein; contains similarity to Interpro domains IPR002456 (GPCR, family 3, gamma-aminobutyric acid receptor, type B1), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
50	C49A9.7	C49A9.7	n/a	chrIV 6,203,875	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001681 (Neurokinin receptor), IPR005395 (Neuropeptide FF receptor), IPR005384 (Duffy antigen/chemokine receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)