UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F25D1.3	F25D1.3	9e-110	chrV 10,529,632	contains similarity to Pfam domain PF06083 Interleukin-17 contains similarity to Interpro domain IPR010345 (Interleukin-17)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	tag-241	C34E11.3	n/a	chrX 11,831,339	C. elegans TAG-241 protein; contains similarity to Interpro domains IPR010978 (tRNA-binding arm), IPR009061 (Putative DNA binding), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
5	R07B1.5	R07B1.5	n/a	chrX 9,865,660	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
6	C52D10.1	C52D10.1	n/a	chrIV 17,188,302	contains similarity to Interpro domain IPR011935 (Conserved hypothetical protein CHP02231)
7	C13C12.2	C13C12.2	n/a	chrV 12,524,627	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
8	pqn-26	DY3.5	n/a	chrI 8,774,608	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
9	C50D2.1	C50D2.1	n/a	chrII 113,049
10	inx-12	ZK770.3	n/a	chrI 3,757,299	inx-12 (innexin=invertebrate connexin analogue) encodes a protein of the innexin family; innexins are gap junction proteins similar in function, though dissimilar in sequence to the vertebrate connexins; innexins are the only known gap junction proteins in invertebrates; inx-12 and inx-13 appear to be a tandom duplication; RNA interference of inx-12 results in an arrest at the L1 larval stage with fluid filled dead rods; this phenotype and sequence homology to Drosophila innexins suggest that INX-12 may be required to form gap junctions between the excretory canal and hypodermis, thus playing an essential role in osmoregulation; an INX-12::GFP fusion protein is expressed in the excretory canal.
11	tag-198	F09G8.2	n/a	chrIII 8,269,509	C. elegans TAG-198 protein; contains similarity to Pfam domain PF03265 Deoxyribonuclease II contains similarity to Interpro domain IPR004947 (Deoxyribonuclease II)
12	F01G10.6	F01G10.6	n/a	chrIV 10,226,957	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
13	cyp-13A2	T10B9.7	n/a	chrII 9,785,530	C. elegans CYP-13A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
14	C27C7.2	C27C7.2	n/a	chrI 11,433,261	contains similarity to Pfam domain PF01697 (Domain of unknown function)
15	xrn-1	Y39G8C.1	n/a	chrII 14,076,171	xrn-1 encodes a 5'-3' exoribonuclease that is orthologous to Saccharomyces cerevisiae Xrnp1, a key component of the yeast 5'-3' mRNA degradation pathway; in C. elegans, XRN-1 activity is required during embryogenesis for completion of ventral enclosure, the morphogenetic process whereby the ventral epithelial cells cover and seal the interior cells of the embryo; in addition, XRN-1 also plays a role in facilitating RNA interference (RNAi), likely acting in the same pathway as the DCR-1/Dicer ribonuclease; to date, XRN-1 expression has been reported in adult hypodermal and rectal cells.
16	srsx-28	C51E3.3	n/a	chrV 10,153,640	C. elegans SRSX-28 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	F49E11.2	F49E11.2	n/a	chrIV 13,037,470	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
18	F57G12.2	F57G12.2	n/a	chrX 12,158,178	contains similarity to Mus musculus Nuclear protein ZAP3.; SW:ZAP3_MOUSE
19	ztf-2	F13G3.1	n/a	chrI 7,292,255	C. elegans ZTF-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR013993 (Zinc finger, N-recognin, metazoa), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
20	F21F8.6	F21F8.6	n/a	chrV 8,266,564
21	R05A10.6	R05A10.6	n/a	chrIV 14,167,109	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
22	scl-10	F49E11.5	n/a	chrIV 13,049,134	C. elegans SCL-10 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
23	sgn-1	F07H5.2	n/a	chrII 8,782,783	C. elegans SGN-1 protein; contains similarity to Pfam domain PF04790 Sarcoglycan complex subunit protein contains similarity to Interpro domain IPR006875 (Sarcoglycan complex subunit protein)
24	C04F6.2	C04F6.2	n/a	chrX 3,397,298
25	F42A9.8	F42A9.8	n/a	chrIV 8,618,533
26	F12F6.1	F12F6.1	n/a	chrIV 11,586,743	contains similarity to Saccharomyces cerevisiae Putative glycosidase of the cell wall, may have a role in cell wall architecture; SGD:YGR189C
27	app-1	W03G9.4	n/a	chrI 4,965,983	C. elegans APP-1 protein; contains similarity to Pfam domains PF01321 (Creatinase/Prolidase N-terminal domain) , PF00557 (metallopeptidase family M24) contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR000587 (Creatinase)
28	F45B8.3	F45B8.3	n/a	chrX 14,960,981	contains similarity to Interpro domains IPR003267 (Small proline-rich), IPR000694 (Proline-rich region)
29	F44E2.4	F44E2.4	n/a	chrIII 8,835,361	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
30	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
31	K10H10.1	K10H10.1	n/a	chrII 14,491,241	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
32	cpt-6	W01A11.5	n/a	chrV 6,491,977	C. elegans CPT-6 protein; contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
33	F54B11.11	F54B11.11	n/a	chrX 13,580,176	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
34	R07G3.6	R07G3.6	n/a	chrII 7,604,709	contains similarity to Interpro domain IPR000694 (Proline-rich region)
35	T05H10.3	T05H10.3	n/a	chrII 8,049,736
36	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
37	F14B8.6	F14B8.6	n/a	chrX 6,930,764
38	W04H10.1	W04H10.1	n/a	chrII 609,207
39	cyp-37A1	F01D5.9	n/a	chrII 14,015,298	C. elegans CYP-37A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
40	T19A5.1	T19A5.1	n/a	chrV 8,959,477	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF00515 (Tetratricopeptide repeat) (2)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
41	K07E8.6	K07E8.6	n/a	chrII 638,824	contains similarity to Pfam domain PF08565 Cdc37 Hsp90 binding domain contains similarity to Interpro domains IPR004918 (Cdc37), IPR013874 (Cdc37, Hsp90 binding)
42	T28C12.1	T28C12.1	n/a	chrV 6,332,957	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
43	trpa-1	C29E6.2	n/a	chrIV 11,870,347	trpa-1 encodes a transient receptor potential (TRP) ion channel orthologous to the vertebrate and Drosophila TRPA1 channels; in C. elegans, trpa-1 activity is required for specific mechanosensory behaviors such as nose-touch avoidance and touch-mediated foraging; when expressed in mammalian cells, TRPA-1 exhibits channel activity in response to mechanical stimulation; TRPA-1::GFP reporters are expressed in a number of different cell types including sensory neurons, muscle, and epithelial cells.
44	pek-1	F46C3.1	n/a	chrX 11,412,423	pek-1 encodes a predicted transmembrane protein kinase orthologous to human eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3, OMIM:604032), which when mutated leads to Wolcott-Rallison syndrome; PEK-1 is strongly expressed in intestinal cells and is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); PEK-1 may function in the endoplasmic reticulum to phosphorylate eIF2alpha and inhibit protein synthesis in response to endogenous ER stress.
45	hum-6	T10H10.1	n/a	chrX 2,309,009	hum-6 is orthologous to the human gene MYOSIN VIIA (MYO7A; OMIM:276903), which when mutated leads to Usher syndrome type IB.
46	fbn-1	ZK783.1	n/a	chrIII 7,633,447	fbn-1 encodes a protein homologous to the human extracellular matrix protein fibrillin-1 (FBN1) which when mutated leads to Marfan syndrome (OMIM:154700), a connective tissue disorder; in C. elegans, fbn-1 activity is required for completion of molting, particularly the L3/L4 or L4/Adult molts.
47	C18B2.3	C18B2.3	n/a	chrX 3,603,031
48	F47A4.5	F47A4.5	n/a	chrX 9,835,643	contains similarity to Pfam domains PF01734 (Patatin-like phospholipase) , PF00023 (Ankyrin repeat) (5)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR002641 (Patatin), IPR002110 (Ankyrin), IPR001680 (WD40 repeat)
49	lgc-54	T15B7.16	n/a	chrV 6,841,721	C. elegans LGC-54 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
50	mec-5	E03G2.3	n/a	chrX 15,946,401	mec-5 encodes a collagen unique in the number of Gly-X-Y repeats and in the composition of amino acids surrounding these repeats; MEC-5 is required for normal mechanosensory response to gentle touch and for the proper functioning of the touch receptor neurons; mec-5 interacts genetically with mec-4 and mec-10 which encode degenerins (ion channels) expressed in the touch neurons, mec-9, which encodes a protein containing EGF-like and Kunitz/protease inhibitor domains secreted by the touch neurons, and mec-12, which encodes an alpha-tubulin expressed in the touch neurons; these genetic interactions suggest that MEC-5 may play a role in anchoring the degenerin complex to the extracellular matrix; MEC-5 is produced and secreted by hypodermal cells.