UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F22B3.8	F22B3.8	0	chrIV 11,423,572	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	lec-4	C44F1.3	n/a	chrIII 3,772,356	lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro.
4	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
5	F59A6.3	F59A6.3	n/a	chrII 5,009,745	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
6	tag-347	C25G4.4	n/a	chrIV 12,453,128	C. elegans TAG-347 protein; contains similarity to Pfam domains PF01342 (SAND domain) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR010919 (SAND-like), IPR000770 (SAND)
7	T28D6.3	T28D6.3	n/a	chrIII 11,367,475	contains similarity to Arabidopsis thaliana Hypothetical protein LCR14 precursor.; TR:P82729
8	F42G2.2	F42G2.2	n/a	chrII 2,423,776	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
9	C06G4.4	C06G4.4	n/a	chrIII 7,977,442
10	C18H2.4	C18H2.4	n/a	chrIII 7,697,463	C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
11	R11E3.1	R11E3.1	2e-54	chrIV 4,790,837	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
12	B0432.7	B0432.7	n/a	chrII 271,677	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
13	M03E7.3	M03E7.3	n/a	chrV 5,615,596
14	C34G6.1	C34G6.1	n/a	chrI 5,912,249	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
15	C43D7.7	C43D7.7	n/a	chrV 19,319,210	contains similarity to Dictyostelium discoideum Filament-interacting protein.; TR:Q967Y0
16	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
17	C50F7.3	C50F7.3	n/a	chrIV 7,733,257	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
18	grl-22	W03A5.3	n/a	chrIII 5,413,566	grl-22 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
19	C17G10.3	C17G10.3	n/a	chrII 5,583,865
20	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
21	F15D3.6	F15D3.6	n/a	chrI 11,574,794	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
22	K04F1.8	K04F1.8	n/a	chrV 1,667,509
23	W04A4.2	W04A4.2	n/a	chrI 13,683,368	contains similarity to Homo sapiens Hypothetical protein FLJ90033; TR:Q8N2R3
24	T20D4.12	T20D4.12	n/a	chrV 3,397,421	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
25	Y11D7A.1	Y11D7A.1	n/a	chrIV 9,229,724	contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
26	F22F4.4	F22F4.4	n/a	chrX 6,000,544
27	W07B8.3	W07B8.3	n/a	chrV 1,125,705
28	acl-13	F08G5.2	n/a	chrIV 12,411,312	C. elegans ACL-13 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
29	ZK666.2	ZK666.2	n/a	chrII 10,471,714	contains similarity to Homo sapiens ASH1; ENSEMBL:ENSP00000265206
30	ZK218.11	ZK218.11	n/a	chrV 17,107,962	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
31	F56H1.3	F56H1.3	n/a	chrI 5,732,820	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR015988 (STAT transcription factor, coiled coil), IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
32	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
33	C25F9.5	C25F9.5	n/a	chrV 19,409,124	contains similarity to Pfam domain PF00176 SNF2 family N-terminal domain contains similarity to Interpro domain IPR000330 (SNF2-related)
34	srz-1	F14F8.3	n/a	chrV 16,676,674	srz-1 encodes a predicted seven-pass G protein-coupled receptor; as loss of srz-1 activity via large-scale RNAi screens results in no obvious abnormalities, the precise role of SRZ-1 in C. elegans development and/or behavior is not yet known.
35	C24A11.6	C24A11.6	n/a	chrI 5,396,389
36	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
37	F48B9.3	F48B9.3	n/a	chrX 2,165,518	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
38	tag-344	B0511.4	0.00004	chrI 10,644,917	C. elegans TAG-344 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)
39	C38D4.7	C38D4.7	n/a	chrIII 4,810,559	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
40	F22H10.2	F22H10.2	n/a	chrX 16,679,072	contains similarity to Interpro domain IPR002395 (HMW kininogen)
41	ncr-1	F02E8.6	n/a	chrX 4,476,155	ncr-1 encodes a large transmembrane glycoprotein with a patched-like domain that is orthologous to human NPC1 (OMIM:257220, mutated in Niemann-Pick type C disease); NCR-1 and NPC1 are eukaryotic members of the resistance-nodulation-division (RND) family of membrane permeases, and have a putative sterol-sensing domain; by homology, NCR-1 is predicted to function in intracellular cholesterol and glycolipid trafficking; in C. elegans, NCR-1 is required for growth and survival in the absence of cholesterol, newly hatched ncr-1 mutant larvae grow poorly on cholesterol-free medium and die at the L1 or L2 stage; NCR-1 is also involved in negative regulation of dauer formation, being required redundantly with NCR-2, a second C. elegans NPC1-like protein, for preventing constitutive dauer formation; dauer formation in ncr-1; ncr-2 double mutants is suppressed by mutations in daf-12, which encodes a steroid hormone receptor, and by overexpression of daf-9, which encodes a cytochrome P450, suggesting that NCR-1 and NCR-2 may function to transport a sterol precursor that is metabolized by DAF-9 to then serve as the DAF-12 ligand.
42	col-64	F52F12.2	n/a	chrI 9,894,637	C. elegans COL-64 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
43	C36C5.14	C36C5.14	n/a	chrV 3,165,115	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
44	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
45	F26H9.8	F26H9.8	n/a	chrI 9,322,465	contains similarity to Pfam domains PF01501 (Glycosyl transferase family 8) , PF06427 (UDP-glucose:Glycoprotein Glucosyltransferase) contains similarity to Interpro domains IPR000886 (Endoplasmic reticulum, targeting sequence), IPR009448 (UDP-glucose:Glycoprotein Glucosyltransferase), IPR002495 (Glycosyl transferase, family 8)
46	B0222.5	B0222.5	n/a	chrV 9,153,570	contains similarity to Pfam domains PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) , PF00086 (Thyroglobulin type-1 repeat) contains similarity to Interpro domains IPR000716 (Thyroglobulin type-1), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
47	R155.3	R155.3	n/a	chrIII 1,973,361	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
48	H05L14.1	H05L14.1	n/a	chrI 7,974,757	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
49	srp-5	C03G6.18	n/a	chrV 7,382,647	srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known.
50	R02D5.3	R02D5.3	n/a	chrV 14,483,717	contains similarity to Arabidopsis thaliana Putative RNA-binding protein.; TR:Q9SHZ5