UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ceh-60	F22A3.5	6e-168	chrX 6,527,181	ceh-60 encodes a homeodomain-containing protein that is a member of the PBX family of homeodomain transcription factors; loss of ceh-60 activity via large-scale RNAi results in reduced fat content, sterility, and variable embryonic lethality.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
4	bath-24	B0047.3	n/a	chrII 2,045,144	C. elegans BATH-24 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
5	srh-201	R03H4.9	n/a	chrV 9,013,008	C. elegans SRH-201 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	T26E4.10	T26E4.10	n/a	chrV 15,798,017	contains similarity to Rattus norvegicus Voltage-dependent T-type calcium channel alpha-1I subunit (CaVT.3).; SW:CCAI_RAT
7	C54D10.10	C54D10.10	n/a	chrV 12,449,327	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
8	fkh-6	B0286.5	n/a	chrII 4,381,579	fkh-6 encodes one of 15 C. elegans forkhead transcription factors; fkh-6 is required for several aspects of male gonadogenesis including asymmetric cell division, cell migration and sex determination and appears to act downstream of tra-1; FKH-6 is specifically expressed in the gonad.
9	F21E9.2	F21E9.2	n/a	chrX 1,329,400
10	K06H6.1	K06H6.1	n/a	chrV 588,891	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
11	JC8.5	JC8.5	n/a	chrIV 13,245,638	contains similarity to Pfam domain PF04442 Cytochrome c oxidase assembly protein CtaG / Cox11 contains similarity to Interpro domain IPR007533 (Cytochrome c oxidase assembly protein CtaG/Cox11)
12	K10D2.5	K10D2.5	n/a	chrIII 5,172,994	contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
13	R11G1.1	R11G1.1	n/a	chrX 3,663,173	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
14	F48G7.9	F48G7.9	n/a	chrV 628,338	contains similarity to Pfam domain PF00130 Phorbol esters/diacylglycerol binding domain (C1 domain) contains similarity to Interpro domains IPR015727 (Protein kinase C mu-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
15	H22K11.3	H22K11.3	n/a	chrX 6,783,682	contains similarity to Candida albicans Hyphally-regulated protein precursor.; SW:P46591
16	F16H6.8	F16H6.8	n/a	chrV 18,214,941	contains similarity to Mycoplasma capricolum CLPA/CLPB family (Fragment).; TR:Q49064
17	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
18	Y38A10A.6	Y38A10A.6	n/a	chrV 6,098,058	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) , PF04851 (Type III restriction enzyme, res subunit) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
19	C45G9.12	C45G9.12	n/a	chrIII 5,070,975
20	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
21	srx-58	C29F3.6	n/a	chrV 15,353,194	C. elegans SRX-58 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
22	C40C9.3	C40C9.3	n/a	chrX 13,647,897	contains similarity to Conus textile Conotoxin scaffold VI/VII.; TR:Q9U653
23	F47B10.6	F47B10.6	n/a	chrX 10,888,627
24	ZK1240.3	ZK1240.3	n/a	chrII 2,321,141	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
25	C09H5.1	C09H5.1	n/a	chrV 8,082,547
26	btb-9	F45C12.4	n/a	chrII 1,729,278	C. elegans BTB-9 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
27	C29F9.12	C29F9.12	n/a	chrIII 121,876
28	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
29	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
30	sra-33	B0304.6	n/a	chrII 4,535,979	C. elegans SRA-33 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
31	Y52B11A.7	Y52B11A.7	n/a	chrI 11,022,105	contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR011050 (Pectin lyase fold/virulence factor), IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
32	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	C50E3.12	C50E3.12	n/a	chrV 7,621,252	contains similarity to Homo sapiens retinitis pigmentosa 1-like 1; ENSEMBL:ENSP00000371923
34	puf-8	C30G12.7	n/a	chrII 7,297,140	C. elegans PUF-8 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
35	srx-1	F59E11.1	n/a	chrV 9,004,313	C. elegans SRX-1 protein; contains similarity to Interpro domains IPR000366 (Fungal pheromone mating factor STE2 GPCR), IPR000276 (GPCR, rhodopsin-like)
36	clec-238	Y102A5C.17	n/a	chrV 16,952,706	C. elegans CLEC-238 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	srx-39	C03A7.6	n/a	chrV 5,157,191	C. elegans SRX-39 protein; contains similarity to Pfam domains PF00001 (7 transmembrane receptor (rhodopsin family)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
38	C33D12.2	C33D12.2	n/a	chrX 3,043,877	C33D12.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C33D12.2 may participate in metal homoeostasis; C33D12.2 is expressed in intestine, body wall muscle, nervous system (including ventral and dorsal nerve cords and head neurons), and adult vulval muscle and reproductive system; C33D12.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C33D12.2 has no obvious function in RNAi assays.
39	nspb-11	F35C5.10	n/a	chrII 12,907,461	C. elegans NSPB-11 protein ;
40	srh-231	C03G6.11	n/a	chrV 7,351,540	C. elegans SRH-231 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003944 (Protease-activated receptor 4)
41	F46C3.2	F46C3.2	n/a	chrX 11,417,473	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
42	C25H3.3	C25H3.3	n/a	chrII 5,694,437	contains similarity to Pfam domain PF03061 Thioesterase superfamily contains similarity to Interpro domains IPR006683 (Thioesterase superfamily), IPR003736 (Phenylacetic acid degradation-related protein)
43	rba-1	K07A1.11	n/a	chrI 9,617,307	C. elegans RBA-1 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
44	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
45	clec-235	F36D3.10	n/a	chrV 16,531,589	C. elegans CLEC-235 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	K06H6.3	K06H6.3	n/a	chrV 582,674	contains similarity to Pfam domain PF04142 Nucleotide-sugar transporter contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR007271 (Nucleotide-sugar transporter)
47	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
48	T27F6.7	T27F6.7	n/a	chrI 12,496,077	contains similarity to Timmia bavarica NADH dehydrogenase subunit 4 (Fragment).; TR:Q94YV9
49	rab-30	Y45F3A.2	n/a	chrIII 10,564,035	rab-30 encodes a rab related protein of the Ras GTPase superfamily.
50	C53D6.6	C53D6.6	n/a	chrIV 9,030,151	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)