UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F21G4.5	F21G4.5	0	chrX 9,906,914	contains similarity to Interpro domain IPR007087 (Zn-finger, C2H2 type)
2	srv-17	C06E7.7	n/a	chrIV 5,868,915	C. elegans SRV-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
3	glr-8	F22A3.3	n/a	chrX 6,508,340	glr-8 encodes a highly divergent putative ionotropic glutamate receptor subunit, unclassifiable as NMDA or non-NMDA (though possibly of the Delta subfamily), and without any clear close homologs in metazoa or plants; glr-8 is expressed in the pharyngeal nervous system, the body wall mechanoreceptors ALM and PLM, and two other neurons (BDU and URB); glr-8 is expressed from embryogenesis to adulthood.
4	C04G6.4	C04G6.4	n/a	chrII 5,082,452	contains similarity to Interpro domain IPR000694 (Proline-rich region)
5	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
6	F25B4.7	F25B4.7	n/a	chrV 5,686,614	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
7	W03G9.3	W03G9.3	n/a	chrI 4,960,459
8	F28C10.3	F28C10.3	n/a	chrX 533,819	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
9	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
10	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
11	cyp-25A6	K06B9.1	n/a	chrIV 4,197,909	C. elegans CYP-25A6 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR000044 (Mycoplasma lipoprotein (MG045))
12	glt-7	W03G1.1	n/a	chrIV 533,911	C. elegans GLT-7 protein; contains similarity to Pfam domain PF00375 Sodium:dicarboxylate symporter family contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
13	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
15	F34D6.2	F34D6.2	n/a	chrII 2,683,818	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
16	W10G6.1	W10G6.1	n/a	chrX 16,245,293	contains similarity to Babesia bovis Merozoite surface antigen-2a2.; TR:Q95UH0
17	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
18	C43H6.7	C43H6.7	n/a	chrX 2,400,426	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR016201 (Plexin-like fold)
19	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
20	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
21	sru-38	R07B5.4	n/a	chrV 9,835,226	C. elegans SRU-38 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
22	F57G4.6	F57G4.6	n/a	chrV 17,643,424	contains similarity to Interpro domains IPR013048 (Meiotic recombination Spo11), IPR006578 (MADF)
23	srh-37	R11G11.9	n/a	chrV 511,858	C. elegans SRH-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	nas-8	C34D4.9	n/a	chrIV 7,117,415	nas-8 encodes an astacin-like metalloprotease.
25	T06D8.2	T06D8.2	n/a	chrII 11,229,674	contains similarity to Pfam domain PF02151 UvrB/uvrC motif contains similarity to Interpro domains IPR009055 (UvrB, C-terminal UvrC-binding), IPR001943 (UvrB/UvrC protein)
26	Y116A8C.22	Y116A8C.22	n/a	chrIV 17,047,371	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
27	B0250.5	B0250.5	n/a	chrV 20,491,021	contains similarity to Pfam domain PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase contains similarity to Interpro domains IPR006115 (6-phosphogluconate dehydrogenase, NAD-binding), IPR013328 (Dehydrogenase, multihelical), IPR015815 (3-hydroxyacid dehydrogenase/reductase), IPR011548 (3-hydroxyisobutyrate dehydrogenase), IPR006183 (6-phosphogluconate dehydrogenase), IPR016040 (NAD(P)-binding), IPR002204 (3-hydroxyisobutyrate dehydrogenase-related, conserved site)
28	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
29	his-32	F17E9.10	n/a	chrIV 8,334,513	his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
30	F13H8.3	F13H8.3	n/a	chrII 6,264,731	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
31	mel-26	ZK858.4	n/a	chrI 9,134,137	mel-26 encodes a MATH and BTB/POZ domain-containing protein that functions as a novel substrate-specific adaptor of the CUL-3-containing E3 ubiquitin ligase; MEL-26 is required maternally for formation of mitotic spindles in the early embryo, and as a component of a ubiquitin ligase complex, for degradation of the microtubule-severing protein MEI-1 at the meiosis to mitosis transition; MEL-26 is also required maternally for embryonic morphogenesis; since MEL-26 contains a meprin-associated Traf homology (MATH) domain, it might be involved in apoptosis.
32	str-52	C45H4.12	n/a	chrV 2,145,082	C. elegans STR-52 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	F12A10.1	F12A10.1	n/a	chrII 5,497,839	contains similarity to Oryza sativa subsp indica Putative uncharacterized protein.; TR:A2YC95
34	ZK669.2	ZK669.2	n/a	chrII 7,937,580	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
35	rib-2	K01G5.6	n/a	chrIII 10,744,609	The rib-2 gene encodes an ortholog of human EXT2, which when mutated leads to hereditary multiple exostoses, type II (OMIM:133701).
36	frk-1	T04B2.2	n/a	chrIV 10,044,780	frk-1 encodes a non-receptor tyrosine kinase orthologous to the human proto-oncogene Fer; frk-1 is an essential gene required early for embryonic cell proliferation and later in embryonic epidermal cells for enclosure, morphogenesis and late stages of differentiation; FRK-1's role in embryonic development is independent of its kinase domain, and when expressed in cultured mammalian cells, FRK-1 disrupts cell adhesion; FRK-1 is initially expressed in all cells of the early embryo where it localizes to nuclei and points of cell-cell contact; later expression is seen in epithelial cells, body wall muscle, and the adult germline, including mature sperm; FRK-1 expression in epidermal cells requires activity of the ELT-1 GATA transcription factor, and FRK-1 localization to the plasma membrane requires PAT-3/Beta-integrin, JAC-1/p120 catenin, and HMP-2/Beta-catenin with which FRK-1 interacts in vitro.
37	C15B12.6	C15B12.6	n/a	chrX 6,498,835
38	C29G2.3	C29G2.3	n/a	chrV 2,581,907
39	Y32B12C.1	Y32B12C.1	n/a	chrV 16,607,269	contains similarity to Interpro domain IPR002625 (Smr protein/MutS2 C-terminal)
40	str-78	Y40H7A.1	n/a	chrIV 15,145,449	C. elegans STR-78 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	lim-6	K03E6.1	n/a	chrX 1,076,785	lim-6 encodes a LIM class homeodomain protein that contains two Zinc-finger-like LIM domains N-terminal to a predicted DNA-binding homeodomain; LIM-6 is predicted to function as a transcription factor whose activity is required for regulating uterine morphogenesis and specific aspects of terminal neuronal differentiation, including normal axonal morphology, full expression of UNC-25/glutamic acid decarboxylase in select GABAergic neurons, and repression of sensory receptor gene expression in the ASEL chemosensory neuron; LIM-6 is expressed in a group of nine chemosensory-, inter-, and motorneurons, uterine toroid cells, spermathecal junction cells, and the binucleate excretory gland cell.
42	Y17G7B.3	Y17G7B.3	n/a	chrII 11,990,838	Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH; OMIM:138760), which when mutated leads to disease.
43	C15C7.1	C15C7.1	n/a	chrX 3,165,079	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR001388 (Synaptobrevin), IPR006012 (Syntaxin/epimorphin, conserved site)
44	F25H2.7	F25H2.7	n/a	chrI 10,559,067	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
45	Y40B10B.1	Y40B10B.1	n/a	chrV 1,960,770	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
46	ubc-12	R09B3.4	n/a	chrI 11,911,676	The ubc-12 gene encodes a ubiquitin-conjugating enzyme whose substrate is NED-8, and which is required for both embryogenesis and terminal hypodermal differentiation; ubc-12(RNAi) mutants either arrest during embryonic development or show pleotropic defects (e.g., vulval eversion during the L4 stage), as well as defective alae.
47	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
48	fbxa-160	C08E3.12	n/a	chrII 1,624,293	C. elegans FBXA-160 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
49	C41D11.4	C41D11.4	n/a	chrI 4,442,876
50	sru-29	C50C10.2	n/a	chrV 9,812,012	C. elegans SRU-29 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)