UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F21D9.4	F21D9.4	0	chrV 19,255,280	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
2	K09D9.3	K09D9.3	n/a	chrV 4,020,029
3	fis-1	F41G3.4	n/a	chrII 6,755,453	C. elegans FIS-1 protein; contains similarity to Interpro domains IPR016543 (Tetratricopeptide repeat 11 Fission 1 protein), IPR011990 (Tetratricopeptide-like helical)
4	R10F2.4	R10F2.4	n/a	chrIII 2,921,110	contains similarity to Interpro domain IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal)
5	Y7A5A.6	Y7A5A.6	n/a	chrX 15,798,435	contains similarity to Schizosaccharomyces pombe Putative transcriptional regulatory protein, phd finger.; TR:Q9HDV4
6	H36L18.1	H36L18.1	n/a	chrX 12,650,135	contains similarity to Pfam domains PF00413 (Matrixin) , PF00045 (Hemopexin) (3)contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
7	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
8	Y116A8C.29	Y116A8C.29	n/a	chrIV 17,094,627	contains similarity to Homo sapiens Class-I MHC-restricted T cell associated molecule; ENSEMBL:ENSP00000227348
9	C26E6.12	C26E6.12	n/a	chrIII 4,931,357	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR014100 (GTP-binding protein Obg/CgtA), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
10	Y56A3A.2	Y56A3A.2	n/a	chrIII 11,856,255	contains similarity to Pfam domain PF02163 Peptidase family M50 contains similarity to Interpro domains IPR008915 (Peptidase M50), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001193 (Peptidase M50, mammalian sterol-regulatory element binding protein)
11	eat-2	Y48B6A.4	n/a	chrII 14,169,168	eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
12	F28B4.1	F28B4.1	n/a	chrX 3,205,615
13	Y53C10A.5	Y53C10A.5	n/a	chrI 12,000,702	contains similarity to Interpro domain IPR000608 (Ubiquitin-conjugating enzyme, E2)
14	T02H6.8	T02H6.8	n/a	chrII 681,180
15	C46E10.5	C46E10.5	n/a	chrII 3,712,130
16	E01G6.2	E01G6.2	n/a	chrX 12,257,730	contains similarity to Streptomyces coelicolor;Streptomyces lividans Putative secreted protein (Putative TWIN ARGININ translocationsreceptor).; TR:Q9RJ68
17	T25D1.3	T25D1.3	n/a	chrX 16,506,246	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
19	clec-229	H02K04.1	n/a	chrV 15,340,763	C. elegans CLEC-229 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
20	T05C1.2	T05C1.2	n/a	chrII 4,482,363
21	T28D6.7	T28D6.7	n/a	chrIII 11,345,403	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
22	F02D10.4	F02D10.4	n/a	chrX 13,458,404	contains similarity to Emericella nidulans Anucleate primary sterigmata protein B.; SW:APSB_EMENI
23	pbo-6	F11C7.1	n/a	chrX 17,431,052	pbo-6/lgc-3 encodes a proton-gated ion channel which has no known function, but that is thought to form functional heterodimers with PBO-5/LGC-2; PBO-6 has no obvious non-nematode orthologs, but is paralogous to PBO-5; while heterologous PBO-6 has no activity when expressed in Xenopus oocytes, it produces strong currents when coexpressed with PBO-5 and stimulated by pH 6.0; PBO-6 is expressed in the most posterior bodywall muscles; unlike pbo-5 mutants, pbo-6(ok1564) mutants and pbo-6(RNAi) animals have no obvious phenotypes.
24	R02F11.2	R02F11.2	n/a	chrV 4,795,145
25	flp-4	C18D1.3	n/a	chrII 10,054,913	C. elegans FLP-4 protein ;
26	srd-66	Y39A3B.4	n/a	chrIII 1,981,723	C. elegans SRD-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	F25B3.2	F25B3.2	n/a	chrV 9,578,510	contains similarity to Lactococcus lactis Oligopeptide transport system permease protein oppC.; SW:OPPC_LACLA
28	nas-14	F09E8.6	n/a	chrIV 13,172,108	nas-14 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-14::GFP promoter fusion is expressed in the pharynx.
29	T21G5.2	T21G5.2	n/a	chrI 6,870,894
30	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
31	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
32	Y116A8C.23	Y116A8C.23	n/a	chrIV 17,054,490	contains similarity to Interpro domain IPR000694 (Proline-rich region)
33	rom-3	Y116A8C.14	n/a	chrIV 16,967,844	C. elegans ROM-3 protein; contains similarity to Pfam domain PF01694 Rhomboid family contains similarity to Interpro domain IPR002610 (Peptidase S54, rhomboid)
34	tbx-11	F40H6.4	n/a	chrIII 6,046,285	tbx-11 encodes a T-box transcription factor that is orthologous to members of the Tbx2 subfamily of T-box transcription factors; by homology, TBX-11 is predicted to function in transcriptional regulation during cellular differentiation, potentially as both an activator and a repressor; however, as loss of tbx-11 function via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of tbx-11 in C. elegans development and/or behavior is not yet known.
35	F54C4.4	F54C4.4	n/a	chrIII 87,055
36	fox-1	T07D1.4	n/a	chrX 2,448,279	fox-1 encodes an RNA-binding protein of the RNA recognition motif (RRM) superfamily of ribonucleic acid binding proteins; during C. elegans development, FOX-1 functions redundantly with other numerator elements to effect proper dosage compensation in the early embryo; in influencing dosage compensation, FOX-1 likely acts via post-transcriptional regulation of xol-1 mRNA levels; in addition to its role in dosage compensation, fox-1 activity is also required for normal male mating behavior; Western analysis and lacZ reporter constructs indicate that FOX-1 is expressed throughout the life cycle, beginning at the 18-20-cell stage of embryogenesis and continuing on through larval stages and into adult hermaphrodites and males; while early embryonic expression of fox-1 is ubiquitous, postembryonic expression is limited to a subset of head and tail neurons.
37	Y49F6C.7	Y49F6C.7	n/a	chrII 3,367,722
38	Y116A8B.5	Y116A8B.5	n/a	chrIV 17,228,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
39	K12H6.12	K12H6.12	n/a	chrII 2,810,497	contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
40	T11F1.3	T11F1.3	n/a	chrII 2,955,703
41	col-147	T06E4.4	n/a	chrV 9,632,778	C. elegans COL-147 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
42	srsx-30	C51E3.5	n/a	chrV 10,159,536	C. elegans SRSX-30 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
43	T13F2.9	T13F2.9	n/a	chrIV 9,768,468	contains similarity to Interpro domain IPR003071 (Orphan nuclear receptor, HMR type)
44	Y69H2.9	Y69H2.9	n/a	chrV 18,703,400	contains similarity to Grapevine leafroll-associated virus 3 Polymerase (Fragment).; TR:Q8V2G8
45	scl-23	B0545.3	n/a	chrIV 88,065	C. elegans SCL-23 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR014044 (SCP-like extracellular)
46	dsl-2	W09G12.1	n/a	chrIV 1,203,808	dsl-2 encodes a putative transmembrane protein whose extracellular domain has single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-2 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
47	osm-6	R31.3	n/a	chrV 11,925,995	osm-6 encodes a novel protein that is orthologous to the IFT52 component of the intraflagellar transport particle; osm-6 activity is required cell autonomously for proper sensory cilium structure and thus for normal ciliated sensory neuron function; OSM-6 is a component of the intraflagellar transport particle subcomplex B, and OSM-6::GFP reporter fusions are expressed exclusively in ciliated sensory neurons.
48	C31H2.4	C31H2.4	n/a	chrX 5,157,381	C31H2.4 encodes a possible 4-hydroxyphenylpyruvate dioxygenase, orthologous to human HPDL/GLOXD1, and paralogous to HPD-1 and human HPD (OMIM:609695, mutated in tyrosinemia type III); C31H2.4 has no obvious function in mass RNAi experiments.
49	dyb-1	F47G6.1	n/a	chrI 1,486,779	The dyb-1 gene encodes a homolog of mammalian alpha-dystrobrevin (DTNA; OMIM:601239), mutation of which can lead to left ventricular noncompaction with congenital heart defects.
50	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)