UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F21D12.3	F21D12.3	0	chrII 7,321,346	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane), IPR000920 (Myelin P0 protein)
2	nac-1	F31F6.6	n/a	chrX 14,896,719	nac-1 encodes a low-affinity sodium-coupled dicarboxylate transporter homologous to INDY in D. melanogaster and to mammalian NaDC1 and NaDC3; nac-1 has no obvious function in either mass or individual RNAi assays; nac-1 is expressed in the intestine, in larvae and adults.
3	ubc-18	R01H2.6	n/a	chrIII 7,068,071	ubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and other class B synthetic multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 are not yet known.
4	fbxb-74	R08C7.9	n/a	chrIV 4,438,735	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
5	srh-128	Y47G7B.1	n/a	chrII 2,704,344	C. elegans SRH-128 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	C49D10.10	C49D10.10	n/a	chrII 3,875,377	C49D10.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C49D10.10 has no clear orthologs in other organisms.
7	F45C12.2	F45C12.2	n/a	chrII 1,732,740	contains similarity to Interpro domains IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
8	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
9	his-38	K03A1.6	n/a	chrX 7,309,668	his-38 encodes an H4 histone; by homology, HIS-38 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-38 is a replication-dependent histone locus that does not reside in a cluster, but exists as a single histone locus on the X chromosome.
10	F59A2.5	F59A2.5	n/a	chrIII 3,405,129	F59A2.5 encodes a moderately small (123-residue) protein; F59A2.5 is orthologous to Brugia 14979.m04575, and more distantly similar to budding yeast Pcc1p, to human CTAG1B (OMIM:300156, cancer antigen), CTAG2 (OMIM:300396, melanoma antigen), and LAGE3 (OMIM:300060), and to many other uncharacterized proteins, ~80-200 residues long, in animals, fungi, and plants; F59A2.5 is required for fertility and embryonic development in mass RNAi assays and is bound by CKU-80 in two-hybrid assays; F59A2.5 is transcriptionally activated by HLH-2 and HLH-8, but has no known expression pattern; while F59A2.5 is putatively secreted and its human homologs are antigens, its yeast homolog Pcc1p is thought to be a transcription factor.
11	ZK507.6	ZK507.6	n/a	chrIII 9,107,905	contains similarity to Pfam domains PF00134 (Cyclin, N-terminal domain) , PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR004367 (Cyclin, C-terminal), IPR014400 (Cyclin, A/B/D/E)
12	tag-189	T04A8.12	n/a	chrIII 4,706,131	C. elegans TAG-189 protein ; contains similarity to Cricetulus griseus Post-GPI-attachment to proteins 2.; TR:Q2ABP2
13	C02B8.2	C02B8.2	n/a	chrX 8,144,673
14	F27C8.2	F27C8.2	n/a	chrIV 9,597,886	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
15	F56G4.4	F56G4.4	n/a	chrI 11,377,362	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR000533 (Tropomyosin), IPR001202 (WW/Rsp5/WWP)
16	col-168	T10E10.1	n/a	chrX 6,326,741	C. elegans COL-168 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
17	F31C3.3	F31C3.3	n/a	chrI 15,045,790	contains similarity to Interpro domain IPR001000 (Glycoside hydrolase, family 10)
18	ced-12	Y106G6E.5	n/a	chrI 10,224,961	ced-12 is required both for phagocytotic engulfment of dying (apoptotic) cells, and for normal migrations of healthy cells during development.
19	Y106G6H.15	Y106G6H.15	n/a	chrI 10,473,965	contains similarity to Pfam domain PF07160 Protein of unknown function (DUF1395) contains similarity to Interpro domain IPR009829 (Protein of unknown function DUF1395)
20	elb-1	Y41C4A.10	n/a	chrIII 11,719,034	elb-1 encodes an Elongin B ortholog required for chromosome condensation and segregation during mitosis and meiotic division II, and also for cell proliferation (probably through degradation of CKI-1); elb-1(RNAi) animals tend to arrest at the second meiotic cell division, with escapers showing many other defects in chromosomal dynamics and cell cycle control such as abnormal pronuclear rotation and cortical protrusion, aberrant chromosomal structures in the intestine, and deficient germ cell proliferation; ELB-1 interacts with ELC-1 and ELC-2 in bacterial two-hybrid experiments.
21	flp-22	F39H2.1	n/a	chrI 8,659,426	C. elegans FLP-22 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family contains similarity to Interpro domain IPR001651 (Gastrin/cholecystokinin peptide hormone)
22	F10E7.11	F10E7.11	n/a	chrII 7,121,124	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR000949 (ELM2)
23	efl-1	Y102A5C.18	n/a	chrV 16,962,099	efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.
24	bath-34	W02A11.5	n/a	chrI 12,751,040	C. elegans BATH-34 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
25	F36A2.8	F36A2.8	n/a	chrI 8,811,005	contains similarity to Pfam domain PF05005 Janus/Ocnus family (Ocnus) contains similarity to Interpro domain IPR007702 (Janus/Ocnus)
26	C24D10.4	C24D10.4	n/a	chrIV 5,160,919
27	F26D10.11	F26D10.11	n/a	chrIV 17,276,156	F26D10.11 encodes an ortholog of murine TMHS (mutated in hurry-scurry/hscy mice), a predicted tetraspan membrane protein required for stereociliary function and a possible ortholog of human DFNB53; the cysteine mutated in hscy mice is conserved in F26D10.11.
28	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
29	ZC395.11	ZC395.11	n/a	chrIII 5,286,154
30	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
31	T12F5.1	T12F5.1	n/a	chrI 3,742,059
32	ced-6	F56D2.7	n/a	chrIII 5,596,872	ced-6 encodes an Src homology (SH) 3 and phosphotyrosine-binding (PTB) domain-containing adaptor protein, orthologous to human CED-6/GULP, that is required for cell corpse engulfment during apoptosis; CED-6 is bound by the phosphotyrosine binding motif in the cytoplasmic tail of the transmembrane protein CED-1, and and within phagocytic cells this interaction may be part of a signal transduction pathway that promotes apoptotic cell engulfment.
33	cic-1	H14E04.5	n/a	chrIII 2,397,836	C. elegans CIC-1 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
34	his-47	B0035.7	n/a	chrIV 11,324,148	his-47 encodes an H2A histone; by homology, HIS-47 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-47 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
35	M03F4.4	M03F4.4	n/a	chrX 4,957,667
36	vet-6	F44F1.7	n/a	chrI 13,271,377	vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
37	T10C6.5	T10C6.5	n/a	chrV 16,023,741	contains similarity to Pfam domain PF04889 Cwf15/Cwc15 cell cycle control protein contains similarity to Interpro domain IPR006973 (Cwf15/Cwc15 cell cycle control protein)
38	fzr-1	ZK1307.6	n/a	chrII 9,642,652	fzr-1 encodes a WD repeat-containing protein homologous to Cdh1/Hct1/FZR (OMIM:603619), a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C) required for anaphase initiation and exit from mitosis; FZR-1 is required for fertility, and also functions redundantly with lin-35/Rb to for normal embryogensis and control of postembryonic cell proliferation; FZR-1 probably regulates the levels of G1 cyclins, degradation of which is critical for G1 arrest.
39	ttr-53	T14G10.3	n/a	chrIV 10,158,369	C. elegans TTR-53 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
40	fbxb-31	M151.5	n/a	chrII 3,638,541	C. elegans FBXB-31 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
41	clec-230	C29F3.5	n/a	chrV 15,348,475	C. elegans CLEC-230 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
42	F59A3.4	F59A3.4	n/a	chrI 5,508,149	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
43	F22B8.3	F22B8.3	n/a	chrV 16,091,524	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	F10E9.7	F10E9.7	n/a	chrIII 8,306,002	contains similarity to Interpro domain IPR016193 (Cytidine deaminase-like)
45	his-59	F55G1.2	n/a	chrIV 7,488,436	his-59 encodes an H3 histone; by homology, HIS-59 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-59 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
46	Y48A6C.3	Y48A6C.3	n/a	chrIII 11,118,099	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR015880 (Zinc finger, C2H2-like), IPR013026 (Tetratricopeptide region), IPR007087 (Zinc finger, C2H2-type)
47	mxl-2	F40G9.11	n/a	chrIII 187,571	C. elegans MXL-2 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
48	Y48E1B.4	Y48E1B.4	n/a	chrII 13,562,596	contains similarity to Buchnera aphidicola Flagellar hook-length control protein.; SW:FLIK_BUCAP
49	T25B9.8	T25B9.8	n/a	chrIV 10,767,369	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
50	K05C4.7	K05C4.7	n/a	chrI 14,738,206	contains similarity to Interpro domains IPR016617 (Uncharacterised conserved protein UCP013899, metal binding), IPR016024 (Armadillo-type fold)