UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F21C10.6	F21C10.6	7e-84	chrV 9,124,712	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
2	Y65A5A.1	Y65A5A.1	n/a	chrIV 16,399,303	contains similarity to Interpro domain IPR001092 (Basic helix-loop-helix dimerization domain bHLH)
3	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
4	wrn-1	F18C5.2	n/a	chrII 6,557,068	wrn-1 encodes an ortholog of human WRN, which when mutated leads to Werner syndrome (OMIM:277700), and one of four C. elegans homologs of the RecQ DNA helicase family that includes E. coli RecQ; by homology, WRN-1 is predicted to function as a helicase, DNA-dependent ATPase, and exonuclease that plays a key role in DNA replication, recombination, and repair; RNA interference studies in C. elegans and the enhancement of many of the resulting phenotypes by ionizing radiation indicate that wrn-1 affects life span and aging and acts at a DNA damage checkpoint; the wrn-1 phenotypes such as premature aging are similar to those of Werner syndrome; immunolocalization studies indicate that WRN-1 expression is nuclear in cells at the embryonic, larval and adult stages.
5	nas-21	T11F9.5	n/a	chrV 11,473,207	nas-21 encodes an astacin-like metalloprotease.
6	srx-135	F09F3.11	n/a	chrV 13,860,290	C. elegans SRX-135 protein ;
7	C06E4.5	C06E4.5	n/a	chrIV 7,255,611	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
8	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
9	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
10	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
11	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	C14E2.2	C14E2.2	n/a	chrX 1,808,144	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
13	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	srh-36	T03D3.4	n/a	chrV 2,820,623	C. elegans SRH-36 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F56E10.3	F56E10.3	n/a	chrV 82,911	contains similarity to Pfam domain PF06371 Diaphanous GTPase-binding Domain contains similarity to Interpro domain IPR010473 (Diaphanous GTPase-binding)
16	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	F33C8.2	F33C8.2	n/a	chrX 14,722,337	contains similarity to Interpro domain IPR003382 (Flavoprotein)
18	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
20	srd-21	W06G6.3	n/a	chrV 16,630,499	C. elegans SRD-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	F46C3.2	F46C3.2	n/a	chrX 11,417,473	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
22	nhr-233	Y32B12B.6	n/a	chrV 16,570,335	C. elegans NHR-233 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	mls-1	H14A12.4	n/a	chrIII 7,461,052	mls-1 encodes a T-box transcription factor orthologous to members of the Tbx1 subfamily of T-box transcription factors (OMIM:602054, mutations in human TBX1 are associated with the developmental disorder DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS)); MLS-1 is required for fate specification of the eight nonstriated uterine muscle cells generated during postembryonic development, and ectopic expression of MLS-1 is sufficient for uterine muscle specification in other mesodermal lineages; mls-1 reporter gene expression is detected in uterine progenitors and differentiated uterine muscles, Type 2 vulval muscles, the left and right intestinal muscles, and the anal depressor muscle; mls-1 expression is positively regulated by the basic helix-loop-helix transcription factors HLH-8/Twist and HLH-2/Daughterless.
24	C54G10.1	C54G10.1	n/a	chrV 14,641,219	contains similarity to Homo sapiens similar to secreted gel-forming mucin; ENSEMBL:ENSP00000328427
25	T09B4.2	T09B4.2	n/a	chrI 6,184,694
26	srw-111	M01G12.4	n/a	chrI 12,124,188	C. elegans SRW-111 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
27	F21C10.1	F21C10.1	0.003	chrV 9,132,804	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
28	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
29	K04E7.1	K04E7.1	n/a	chrX 6,462,585
30	ZK353.2	ZK353.2	n/a	chrIII 8,398,849	contains similarity to Interpro domain IPR002952 (Eggshell protein)
31	clec-168	F38A1.7	n/a	chrIV 1,258,213	C. elegans CLEC-168 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	R160.2	R160.2	n/a	chrX 4,376,697
33	T27F6.4	T27F6.4	n/a	chrI 12,485,310	contains similarity to Saccharomyces cerevisiae Mid-Two Like 1; SGD:YGR023W
34	F29C12.3	F29C12.3	n/a	chrII 13,107,433	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
35	nhr-33	ZK455.6	n/a	chrX 11,319,573	C. elegans NHR-33 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	R04B5.7	R04B5.7	n/a	chrV 10,089,830	contains similarity to Rattus norvegicus Protein tyrosine phosphatase TD14.; TR:O88902
38	C08A9.8	C08A9.8	n/a	chrX 17,103,774	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
39	F54D10.4	F54D10.4	n/a	chrII 3,806,515
40	ceh-14	F46C8.5	n/a	chrX 7,530,621	ceh-14 encodes a LIM homeodomain protein orthologous to Drosophila Lim3 and the vertebrate Lhx3 and Lhx4 proteins; ceh-14 is required for specification of the AFD thermosensory neurons and for normal thermotactic behavior; a ceh-14::GFP reporter fusion is expressed in head and tail neurons, including the AFD thermosensory neurons, during late embryonic, larval, and adult stages. Animals triply mutant for the LIM homeobox genes ceh-14, lin-11, and ttx-3 which are required for function of the AFD, AIZ, and AIY neurons, respectively, exhibit a basic cryophilic thermotaxis response suggesting that, in C. elegans, there is more than one pathway for integration of thermosensory input.
41	F36A4.11	F36A4.11	n/a	chrIV 4,245,281
42	bath-45	F29C12.5	n/a	chrII 13,123,821	C. elegans BATH-45 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) (2), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	clec-247	Y51A2A.1	n/a	chrV 18,285,606	C. elegans CLEC-247 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
44	C50H11.1	C50H11.1	n/a	chrV 3,090,166	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
45	EGAP2.2	EGAP2.2	n/a	chrII 5,230,269
46	F14H12.7	F14H12.7	n/a	chrX 4,362,080
47	sre-56	C50E10.8	n/a	chrII 12,326,444	C. elegans SRE-56 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR002090 (Na+/H+ exchanger, isoform 6 (NHE6)), IPR000276 (GPCR, rhodopsin-like)
48	srt-45	M162.3	n/a	chrV 19,780,434	C. elegans SRT-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	T14G8.2	T14G8.2	n/a	chrX 12,858,701	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
50	F59H6.6	F59H6.6	n/a	chrII 2,011,980	contains similarity to Interpro domain IPR009057 (Homeodomain-like)