UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	mrp-6	F20B6.3	0	chrX 4,182,153	C. elegans MRP-6 protein; contains similarity to Pfam domains PF00664 (ABC transporter transmembrane region) (2), PF00005 (ABC transporter) (2)contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR001140 (ABC transporter, transmembrane region), IPR009147 (Cystic fibrosis transmembrane conductance regulator), IPR003593 (AAA+ ATPase, core)
2	C01A2.2	C01A2.2	n/a	chrI 13,397,863	contains similarity to Streptomyces coelicolor Putative sugar transporter integral membrane protein.; TR:Q9K489
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
5	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
6	W04A4.4	W04A4.4	n/a	chrI 13,676,809	contains similarity to Pfam domain PF00648 Calpain family cysteine protease contains similarity to Interpro domain IPR001300 (Peptidase C2, calpain)
7	F14B6.2	F14B6.2	n/a	chrI 12,220,319	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
8	ZK287.4	ZK287.4	n/a	chrV 9,682,882	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR000694 (Proline-rich region), IPR006150 (Cysteine-rich repeat)
9	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
10	cyld-1	F40F12.5	n/a	chrIII 9,904,526	F40F12.5 encodes an ortholog of human CYLD1 (OMIM:605018, mutated in cylindromatosis); CYLD1 binds several members of the NF-kappaB signalling pathway, and can deubiquitinate target proteins.
11	elc-2	W03H1.2	n/a	chrX 1,777,746	elc-2 encodes a protein containing a Skp1 dimerisation domain that has homology to human transcription elongation factor B (SIII), polypeptide I (15kD, elonginsC).
12	F39C12.1	F39C12.1	n/a	chrX 4,843,950	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
13	F49E10.1	F49E10.1	n/a	chrX 5,899,725	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
14	srh-7	K09D9.7	n/a	chrV 4,009,007	C. elegans SRH-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	Y57A10B.2	Y57A10B.2	n/a	chrII 12,376,431	contains similarity to Homo sapiens RNA binding protein; ENSEMBL:ENSP00000301740
16	C34E7.3	C34E7.3	n/a	chrX 12,931,101	contains similarity to Plasmodium falciparum Ribonuclease, putative.; TR:Q8ICL5
17	F42C5.10	F42C5.10	n/a	chrIV 7,323,684	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region)
18	CD4.5	CD4.5	n/a	chrV 5,590,729
19	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
20	srd-70	F48F5.4	n/a	chrV 20,450,660	C. elegans SRD-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	flp-32	R03A10.2	n/a	chrX 15,434,497	C. elegans FLP-32 protein ;
22	F11A5.4	F11A5.4	n/a	chrV 16,195,957	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
23	F22G12.5	F22G12.5	n/a	chrI 13,172,567	contains similarity to Interpro domain IPR001765 (Carbonic anhydrase)
24	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
25	F31F4.11	F31F4.11	n/a	chrV 663,441	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
26	pha-2	M6.3	n/a	chrX 635,373	pha-2 encodes a homeodomain protein that is orthologous to vertebrate Hex proteins required for the development of B lymphocytes and organs derived from foregut endoderm; in C. elegans, pha-2 is essential for proper development and morphogenesis of the pm5 pharyngeal muscles cells during late stages of embryogenesis; in regulating pm5 fate specification, PHA-2 appears to act downstream of the organ identity factor PHA-4, and upstream of ceh-22, whose expression it may negatively regulate in pm5; a rescuing PHA-2::GFP reporter is expressed in pharyngeal cells, intestinal-rectal cells, and postembryonic head neurons.
27	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
28	F56F11.1	F56F11.1	n/a	chrIII 2,892,177
29	D1044.1	D1044.1	n/a	chrIII 5,545,251	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
30	C01B12.2	C01B12.2	n/a	chrII 20,848	contains similarity to Pfam domain PF01342 SAND domain contains similarity to Interpro domains IPR010919 (SAND-like), IPR000770 (SAND)
31	srh-32	Y26G10.2	n/a	chrV 17,702,215	C. elegans SRH-32 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	sri-45	K07E8.9	n/a	chrII 660,949	C. elegans SRI-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	R05A10.3	R05A10.3	n/a	chrIV 14,175,025	contains similarity to Saccharomyces cerevisiae <b><u>C</u></b>onserved <b><u>O</u></b>ligomeric <b><u>G</u></b>olgi complex <b><u>1</u></b><br> Complexed with Cog8p; interacts with Cog2p; SGD:YGL223C
34	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
35	lgc-54	T15B7.16	n/a	chrV 6,841,721	C. elegans LGC-54 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
36	srw-7	R08F11.5	n/a	chrV 3,806,992	C. elegans SRW-7 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
37	T15B7.10	T15B7.10	n/a	chrV 6,811,130	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
38	T13A10.1	T13A10.1	n/a	chrIV 6,276,666	contains similarity to Danio rerio Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).; SW:Q8JFV8
39	dkf-1	W09C5.5	n/a	chrI 13,644,346	C. elegans DKF-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) (2)contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR001849 (Pleckstrin-like), IPR000719 (Protein kinase, core), IPR015727 (Protein kinase C mu-related), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
40	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
41	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
42	T02H6.5	T02H6.5	n/a	chrII 687,130	contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
43	ncr-2	F09G8.4	n/a	chrIII 8,261,990	ncr-2 encodes a homolog of human NPC1, which when mutated leads to Niemann-Pick disease, type C (OMIM:257220).
44	F11G11.4	F11G11.4	n/a	chrII 4,861,326
45	ZK688.7	ZK688.7	n/a	chrIII 7,911,165
46	F16G10.13	F16G10.13	n/a	chrII 2,395,441	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
47	str-39	F37B4.12	n/a	chrV 2,878,851	C. elegans STR-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002355 (Multicopper oxidase, copper-binding site)
48	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
49	C36C5.15	C36C5.15	n/a	chrV 3,168,358	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
50	Y54E2A.10	Y54E2A.10	n/a	chrII 14,791,729	contains similarity to Dictyostelium discoideum Protein-tyrosine phosphatase 3 (EC 3.1.3.48) (Protein-tyrosine-sphosphate phosphohydrolase 3).; SW:PTP3_DICDI