UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F19D8.2	F19D8.2	8e-117	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
2	sru-2	C33A12.13	n/a	chrIV 9,486,898	C. elegans SRU-2 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
3	str-84	F59E11.13	n/a	chrV 8,980,200	C. elegans STR-84 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	unc-39	F56A12.1	n/a	chrV 14,374,572	unc-39 encodes a homeodomain transcription factor that belongs to the Six4/5 family of homeodomain proteins that includes human Six5; UNC-39 is required for axonal pathfinding in anterior-derived neurons and for specification of most mesodermal cell types and may regulate a developmental decision between migration and differentiation; UNC-39 is expressed in the embryo in anterior neurons, posteriorly derived mesoderm (somatic gonad, M mesoblast, and possibly the coelomocytes and muIntR), the CAN neurons, and body wall muscle.
5	rfc-2	F58F6.4	n/a	chrIV 1,350,136	rfc-2 encodes a member of the AAA family that are ATPases associated with DNA replication and has highest similarity to the mouse Replication factor C 40 kDa subunit, and affects embryonic viability, fertility, and locomotion in a large-scale RNAi screen.
6	clec-247	Y51A2A.1	n/a	chrV 18,285,606	C. elegans CLEC-247 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
7	F39H12.2	F39H12.2	n/a	chrX 832,122	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
8	btb-3	B0047.2	n/a	chrII 2,043,575	C. elegans BTB-3 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
9	T21D12.7	T21D12.7	n/a	chrIV 290,077	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR013090 (Phospholipase A2, active site), IPR006150 (Cysteine-rich repeat)
10	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
11	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	K04E7.1	K04E7.1	n/a	chrX 6,462,585
13	srx-133	F09F3.4	n/a	chrV 13,849,303	C. elegans SRX-133 protein ;
14	C44C10.5	C44C10.5	n/a	chrX 11,691,705	contains similarity to Homo sapiens Structural maintenance of chromosomes protein 1A; ENSEMBL:ENSP00000323421
15	R05D11.7	R05D11.7	n/a	chrI 8,601,675	contains similarity to Pfam domain PF08648 Protein of unknown function (DUF1777) contains similarity to Interpro domain IPR013957 (Protein of unknown function DUF1777)
16	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
17	F45C12.16	F45C12.16	n/a	chrII 1,737,908	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
18	T09B4.2	T09B4.2	n/a	chrI 6,184,694
19	kup-1	F10C2.2	n/a	chrV 12,036,541	kup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.
20	C39E9.11	C39E9.11	n/a	chrIV 13,092,485	C39E9.11 is orthologous to the human gene PAPILLARY RENAL CELL CARCINOMA (TRANSLOCATION-ASSOCIATED) (PRCC; OMIM:179755), which when mutated leads to disease.
21	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
23	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
24	K11B4.2	K11B4.2	n/a	chrI 14,798,156	contains similarity to Tetraodon nigroviridis UPF0402 protein.; SW:Q4S3C1
25	lem-2	W01G7.5	n/a	chrII 14,064,559	C. elegans LEM-2 protein; contains similarity to Pfam domain PF03020 LEM domain contains similarity to Interpro domains IPR013142 (LEM-like region), IPR003887 (Lamino-associated polypeptide 2/emerin), IPR011015 (LEM-like fold)
26	grd-11	K02E2.2	n/a	chrV 20,356,705	grd-11 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; grd-11 has no obvious function in RNAi assays.
27	spat-1	F57C2.6	n/a	chrII 14,531,337	spat-1 encodes a divergent ortholog of Drosophila melanogaster AURORA BOREALIS (BORA) and human BORA (OMIM:610510); SPAT-1 is specifically required for PAR protein-dependent cell-polarity; RNAi of spat-1 weakly suppresses the embryonic lethality of par-2(it5ts) at restrictive temperature.
28	str-244	C50H11.9	n/a	chrV 3,058,396	C. elegans STR-244 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	T12D8.4	T12D8.4	n/a	chrIII 13,628,781	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
30	Y39A3B.1	Y39A3B.1	n/a	chrIII 2,007,600
31	Y54G11A.1	Y54G11A.1	n/a	chrII 14,262,654	contains similarity to Mesocricetus auratus Nucleolin (Protein C23).; SW:NUCL_MESAU
32	twk-32	F53C11.6	n/a	chrV 13,798,574	C. elegans TWK-32 protein; contains similarity to Pfam domains PF00041 (Fibronectin type III domain) (2), PF07885 (Ion channel) (2)contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR009147 (Cystic fibrosis transmembrane conductance regulator), IPR013099 (Ion transport 2)
33	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	B0284.2	B0284.2	n/a	chrIII 4,382,911	contains similarity to Homo sapiens Isoform 1 of Progesterone-induced-blocking factor 1; ENSEMBL:ENSP00000317144
35	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
36	B0035.16	B0035.16	n/a	chrIV 11,295,988	contains similarity to Pfam domain PF03054 tRNA methyl transferase contains similarity to Interpro domains IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004506 (tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
37	C25G6.1	C25G6.1	n/a	chrX 1,271,143	contains similarity to Pfam domain PF03803 Scramblase contains similarity to Interpro domain IPR005552 (Scramblase)
38	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
39	F58E1.13	F58E1.13	n/a	chrII 1,695,343
40	T08A9.6	T08A9.6	n/a	chrX 7,312,318	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
41	mls-1	H14A12.4	n/a	chrIII 7,461,052	mls-1 encodes a T-box transcription factor orthologous to members of the Tbx1 subfamily of T-box transcription factors (OMIM:602054, mutations in human TBX1 are associated with the developmental disorder DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS)); MLS-1 is required for fate specification of the eight nonstriated uterine muscle cells generated during postembryonic development, and ectopic expression of MLS-1 is sufficient for uterine muscle specification in other mesodermal lineages; mls-1 reporter gene expression is detected in uterine progenitors and differentiated uterine muscles, Type 2 vulval muscles, the left and right intestinal muscles, and the anal depressor muscle; mls-1 expression is positively regulated by the basic helix-loop-helix transcription factors HLH-8/Twist and HLH-2/Daughterless.
42	pop-1	W10C8.2	n/a	chrI 2,826,881	pop-1 encodes an HMG box-containing protein that is the sole C. elegans member of the TCF/LEF family of transcription factors; in C. elegans, POP-1 functions as a component of the canonical and noncanonical Wnt signaling pathways that are required for cell migrations and binary cell fate decisions associated with asymmetric cell division, respectively; in yeast two-hybrid assays, the POP-1 N-terminal beta-catenin binding domain interacts with BAR-1/beta-catenin as well as with the more divergent beta-catenin, SYS-1; when coexpressed with SYS-1, POP-1 is able to activate transcription from a promoter with TCF binding sites; during development, maternally provided POP-1 is first detected in the nuclei of maturing oocytes and then in nearly all cells of the early embryo; in sister blastomeres in the early embryo, POP-1 is detected at lower levels in posterior blastomeres, such as E and P3, than in corresponding anterior blastomeres, MS and C; in later developmental stages, POP-1 is detected in a subset of tissues including hypodermal seam cells, gonadal precursors, and the developing vulva; in the vulva, POP-1 also exhibits an asymmetric staining pattern, with sister cells showing high or low levels of POP-1 depending upon their orientation along the anterior/posterior axis of the vulva.
43	fipr-8	C12D8.6	n/a	chrV 10,240,388	C. elegans FIPR-8 protein ; contains similarity to Homo sapiens Keratin-associated protein 19-8; ENSEMBL:ENSP00000372272
44	srd-16	C04E6.9	n/a	chrV 5,899,272	C. elegans SRD-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
45	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
47	nhr-33	ZK455.6	n/a	chrX 11,319,573	C. elegans NHR-33 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	Y56A3A.31	Y56A3A.31	n/a	chrIII 11,986,100	contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
49	C56E6.2	C56E6.2	n/a	chrII 6,525,580	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006036 (Potassium uptake protein TrkA), IPR002078 (RNA polymerase sigma factor 54, interaction)
50	F40E3.6	F40E3.6	n/a	chrI 2,651,225