UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sea-1	F19B10.9	0	chrII 3,672,747	sea-1 encodes a T-box transcription factor; during development, sea-1 functions, zygotically and in a dose-dependent manner, as an autosomal element of the X:A (X chromosome:autosome) ratio that determines C. elegans sex; in opposition to the X signal elements, SEA-1 positively regulates transcription of xol-1, the master sex-determination switch gene that is essential for male development and for setting the proper activity level of the dosage compensation complex; consistent with its role as a regulator of sex determination, SEA-1 is expressed in nuclei of early embryos from approximately the 20- to 100-cell stage of embryogenesis.
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
4	T12G3.6	T12G3.6	n/a	chrIV 12,030,485	contains similarity to Helicobacter pylori Hypothetical protein HP1128.; TR:O25753
5	T12A2.3	T12A2.3	n/a	chrIII 6,241,137
6	btb-6	F45C12.7	n/a	chrII 1,715,821	C. elegans BTB-6 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
7	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
8	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
9	T24C4.2	T24C4.2	n/a	chrIII 868,674
10	Y6G8.3	Y6G8.3	n/a	chrV 17,602,355	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
11	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
12	K02B12.2	K02B12.2	n/a	chrI 8,512,048	contains similarity to Interpro domain IPR008946 (Nuclear hormone receptor, ligand-binding)
13	C31G12.1	C31G12.1	n/a	chrV 18,180,590	contains similarity to Kaposi's sarcoma-associated herpesvirus K1 glycoprotein (Fragment).; TR:Q9WHA1
14	F41C6.3	F41C6.3	n/a	chrX 6,870,780
15	flh-3	Y11D7A.13	n/a	chrIV 9,270,834	C. elegans FLH-3 protein; contains similarity to Pfam domain PF04500 FLYWCH zinc finger domain contains similarity to Interpro domains IPR007588 (Zinc finger, FLYWCH-type), IPR009057 (Homeodomain-like)
16	R04D3.4	R04D3.4	n/a	chrX 13,288,277	contains similarity to Rattus norvegicus Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkessdisease-associated protein homolog).; SW:AT7A_RAT
17	F28D1.2	F28D1.2	n/a	chrIV 12,375,385	contains similarity to Homo sapiens Myelin transcription factor 1; ENSEMBL:ENSP00000327465
18	F08F3.6	F08F3.6	n/a	chrV 5,419,025	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
19	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
20	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
21	Y43F11A.4	Y43F11A.4	n/a	chrII 12,120,633	contains similarity to Bos taurus Phosphatidylinositol 3-kinase regulatory gamma subunit (PI3-kinasesp85-gamma subunit) (PtdIns-3-kinase p85-gamma) (p55PIK).; SW:P55G_BOVIN
22	fbxb-16	ZC204.10	n/a	chrII 1,651,202	fbxb-16 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-16 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
23	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
25	Y106G6D.1	Y106G6D.1	n/a	chrI 10,108,184	contains similarity to Methanocaldococcus jannaschii DNA double-strand break repair rad50 ATPase.; SW:Q58718
26	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
27	dsl-6	H02I12.4	n/a	chrIV 11,397,523	dsl-6 encodes a putative transmembrane protein whose extracellular domain has a single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-6 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
28	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
29	bath-10	Y49F6C.4	n/a	chrII 3,375,923	C. elegans BATH-10 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
30	T04D3.5	T04D3.5	n/a	chrI 13,330,023
31	nhr-2	C32F10.6	n/a	chrI 5,819,797	nhr-2 encodes a member of the nuclear hormone receptor family that is required for embryonic viability and morphogenesis; expressed during embryogenesis.
32	ZK816.4	ZK816.4	n/a	chrX 3,349,628
33	fbxb-62	F55C9.8	n/a	chrV 19,301,505	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
34	F13H10.1	F13H10.1	n/a	chrIV 11,004,784	contains similarity to Oryza sativa Putative pM5 collagenase.; TR:Q93W04
35	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
36	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
37	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
38	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	F15A4.10	F15A4.10	n/a	chrII 12,484,765	contains similarity to Saccharomyces cerevisiae Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate; SGD:YOR195W
40	F48C1.5	F48C1.5	n/a	chrI 5,317,876
41	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
42	sdz-22	F56F4.1	n/a	chrI 6,148,622	C. elegans SDZ-22 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
43	F55G7.2	F55G7.2	n/a	chrX 11,930,695	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
44	C47F8.7	C47F8.7	n/a	chrI 12,326,720
45	sdz-25	M116.4	n/a	chrIV 8,405,798	C. elegans SDZ-25 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
46	fbxb-54	K05F6.7	n/a	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
47	fbxb-83	T17A3.6	n/a	chrIII 144,210	C. elegans FBXB-83 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
48	C31H5.4	C31H5.4	n/a	chrI 9,042,426	contains similarity to Oryza sativa P0681F05.20 protein.; TR:Q8GVP7
49	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
50	rgs-8.1	F52D2.2	n/a	chrX 1,953,014	C. elegans RGS-8.1 protein; contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)