UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F19B10.11	F19B10.11	0	chrII 3,652,760	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR009071 (High mobility group box, HMG)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
4	hsp-12.2	C14B9.1	n/a	chrIII 8,138,785	hsp-12.2 encodes a small heat-shock protein that forms heterotetramers with HSP-12.3 and has no chaperone-like activity; structurally, HSP-12.2 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells.
5	col-105	F58F6.2	n/a	chrIV 1,358,519	C. elegans COL-105 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
6	pqn-74	W02A2.3	n/a	chrIV 13,330,430	pqn-74 encodes a protein with two chitin-binding peritrophin-A domains, separated by a glutamine/asparagine (Q/N)-rich ('prion') domain; like CEJ-1 and CPG-2, PQN-74 might participate in eggshell synthesis and early embryonic development, and PQN-74's peritrophin-A domains might enable mechanical cross-linking of chitin.
7	F47D12.5	F47D12.5	n/a	chrIII 6,283,998	contains similarity to Homo sapiens Isoform 1 of Protein zyg-11 homolog B; ENSEMBL:ENSP00000294353
8	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
9	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
10	T02G5.3	T02G5.3	n/a	chrII 7,094,691
11	let-381	F26B1.7	n/a	chrI 6,322,210	let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
12	BE10.3	BE10.3	n/a	chrIII 12,810,237	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
13	F08B6.3	F08B6.3	n/a	chrI 6,759,203	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR000886 (Endoplasmic reticulum, targeting sequence)
14	R53.5	R53.5	n/a	chrII 9,969,980	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
15	pqn-71	T23F1.6	n/a	chrV 15,466,350	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
16	W04A8.5	W04A8.5	n/a	chrI 13,850,230	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
17	F38A5.7	F38A5.7	n/a	chrIV 6,602,016
18	ZK867.2	ZK867.2	n/a	chrX 7,208,303
19	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
20	AH10.3	AH10.3	n/a	chrV 14,144,698	contains similarity to Tomato yellow leaf curl virus Hypothetical 10.9 kDa protein (C4 protein).; SW:YC4_TYLCU
21	F59E11.2	F59E11.2	n/a	chrV 9,002,297	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
22	gnrr-1	F54D7.3	n/a	chrI 4,802,135	F54D7.3 is orthologous to the human gene GONADOTROPIN RELEASING HORMONE RECEPTOR (GNRHR; OMIM:138850), which when mutated leads to disease.
23	C54E10.6	C54E10.6	n/a	chrV 18,808,334	contains similarity to Saccharomyces cerevisiae Spindle Pole Component of molecular weight 24kDa; SGD:YMR117C
24	srw-95	H06H21.2	n/a	chrIV 4,813,069	C. elegans SRW-95 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	sdz-16	F31E9.4	n/a	chrV 17,327,178	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
26	C05E11.3	C05E11.3	n/a	chrX 4,580,554	contains similarity to Mus musculus Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembranesspanning transporter) (Mouse transporter protein) (MTP).; SW:Q60961
27	lgc-16	T01H10.5	n/a	chrX 12,119,573	C. elegans LGC-16 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
28	C06E2.2	C06E2.2	n/a	chrX 8,879,967
29	nhr-15	F33E11.1	n/a	chrV 321,993	nhr-15 is predicted to encode a member of the nuclear hormone receptor family.
30	ife-4	C05D9.5	n/a	chrX 1,105,125	The ife-4 gene encodes a member of the Initiation Factor 4E (eIF4E) family.
31	F59H6.5	F59H6.5	n/a	chrII 2,005,814	contains similarity to Pfam domain PF05970 Eukaryotic protein of unknown function (DUF889) contains similarity to Interpro domains IPR010285 (Protein of unknown function DUF889, eukaryote), IPR003593 (AAA+ ATPase, core), IPR006034 (Asparaginase/glutaminase)
32	srh-16	F55C5.9	n/a	chrV 12,292,985	C. elegans SRH-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	T05H4.10	T05H4.10	n/a	chrV 6,420,809	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
34	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
35	unc-119	M142.1	n/a	chrIII 10,907,547	unc-119 encodes a novel protein that is highly conserved amongst metazoans; unc-119 activity is required for proper development of the nervous system, including axonal branching and fasciculation, and hence, for normal movement, chemosensation, and feeding; unc-119 is expressed pan-neuronally beginning in the early embryo (~60 cells) and continuing through adulthood; although the molecular function of UNC-119 is not yet known, human UNC119, which can rescue C. elegans unc-119 mutant animals, is reported to function as a receptor-associated activator of signal transduction; thus, UNC-119 may be part of a signal transduction pathway that mediates axonal patterning in response to external developmental cues.
36	T22B11.3	T22B11.3	n/a	chrIV 4,684,022	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
37	C18E3.3	C18E3.3	n/a	chrI 4,205,990	contains similarity to Staphylococcus saprophyticus subsp saprophyticus Uro-adherence factor A precursor.; SW:Q4A0V8
38	Y44A6D.6	Y44A6D.6	n/a	chrV 20,807,147	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
39	fbxb-52	K05F6.6	n/a	chrII 1,548,512	C. elegans FBXB-52 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07735 (F-box associated) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR012885 (F-box associated type 2), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
40	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
41	aip-1	F58E10.4	n/a	chrV 14,012,966	aip-1 encodes an AN-1-like zinc finger-containing protein homologous to arsenite-inducible RNA-associated protein (AIRAP), conserved among C. elegans, Drosophila, and mammals; like AIRAP itself, AIP-1 protects cells from arsenite toxicity; AIP-1 is a predicted RNA binding protein that may function in ubiquitin-mediated proteolysis following aresenite treatment; AIP-1 does not appear to be essential for viability, but is expressed at high levels in hypodermal and intestinal cells following such treatment.
42	T15B7.15	T15B7.15	n/a	chrV 6,837,660	contains similarity to Interpro domain IPR000533 (Tropomyosin)
43	W04H10.2	W04H10.2	n/a	chrII 606,109
44	M151.1	M151.1	0.002	chrII 3,642,785
45	rga-2	Y53C10A.4	n/a	chrI 11,982,522	C. elegans RGA-2 protein; contains similarity to Pfam domain PF00620 RhoGAP domain contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR006564 (Zinc finger, PMZ-type), IPR000198 (RhoGAP)
46	srg-10	T04A8.1	n/a	chrIII 4,678,679	C. elegans SRG-10 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
47	Y65A5A.2	Y65A5A.2	n/a	chrIV 16,413,511	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
48	fbxb-93	Y63D3A.9	n/a	chrI 14,083,610	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	F14F4.1	F14F4.1	n/a	chrX 14,926,903	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR000276 (GPCR, rhodopsin-like), IPR001817 (Vasopressin receptor)
50	sri-71	D2062.3	n/a	chrII 2,628,473	C. elegans SRI-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)