UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pes-8	F18G5.2	0	chrX 9,254,218	pes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype.
2	ZC84.6	ZC84.6	n/a	chrIII 9,196,038	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
3	C14C6.7	C14C6.7	n/a	chrV 549,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
4	F55A12.5	F55A12.5	n/a	chrI 5,347,791	contains similarity to Gallus gallus Nucleolin (Protein C23).; SW:P15771
5	clp-2	T04A8.16	n/a	chrIII 4,702,158	clp-2 encodes a large calpain subunit that contains two predicted MIT (microtubule interacting and trafficking) domains and is homologous to the mammalian Calpain 7 proteins and the atypical, nuclear-localized Aspergillus calpain, PalB; by homology, CLP-2 is predicted to function as a calcium-dependent, cysteine protease that is involved in intracellular proteolysis and peptidolysis; however, as loss of clp-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of CLP-2 in C. elegans development and/or behavior is not yet known.
6	M02D8.2	M02D8.2	n/a	chrX 8,739,895
7	nspb-3	F38A5.5	n/a	chrIV 6,594,788	C. elegans NSPB-3 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
8	D1014.6	D1014.6	n/a	chrV 8,122,275	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
9	apt-9	W04G3.4	n/a	chrX 11,070,152	apt-9 gene encodes an ortholog of GGA (Golgi-localizing, gamma-adaptin ear homology, ARF-binding protein), which contains a domain paralogous to the gamma-adaptin subunits of adaptor protein complexes; based on structural similarity, APT-9 may beinvolved in the formation of intracellular transport vesicles.
10	sri-73	C14C6.10	n/a	chrV 565,238	C. elegans SRI-73 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)
11	K09F6.2	K09F6.2	n/a	chrII 2,268,709	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
12	cyp-35B2	K07C6.3	n/a	chrV 3,943,321	C. elegans CYP-35B2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
13	math-24	C46F9.3	n/a	chrII 1,901,084	The C46F9.3 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
14	rhr-2	B0240.1	n/a	chrV 11,729,008	rhr-2 encodes a predicted transmembrane protein with similarity to human Rh blood group antigens proposed to function in inorganic ion transport and metabolism; the role of RHR-2 in C. elegans development or behavior remains unclear, as loss of RHR-2 function via RNA-mediated interference does not result in any abnormalities.
15	F27D9.2	F27D9.2	n/a	chrX 7,674,579	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR000576 (Proton/sugar symporter, LacY), IPR016196 (MFS general substrate transporter)
16	K02E7.10	K02E7.10	n/a	chrII 1,066,288	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
17	F32G8.2	F32G8.2	n/a	chrV 10,552,095	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
18	dao-4	ZC373.6	n/a	chrX 10,075,753	dao-4 encodes a novel protein, conserved amongst nematodes; dao-4 transcripts are expressed at higher levels in wild-type adult animals than in daf-2 mutant adults at 25C, suggesting that dao-4 expression is positively regulated by DAF-2/insulin-like receptor signaling; reduced dao-4 expression in daf-2 mutants is dependent upon DAF-16.
19	nas-22	T11F9.6	n/a	chrV 11,475,004	nas-22 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-22::GFP promoter fusion is expressed in the uterus, uterine and vulval muscles, and uterine seam cell.
20	C05D12.2	C05D12.2	n/a	chrII 11,420,763	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans)
21	C42C1.9	C42C1.9	n/a	chrIV 12,290,184	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
22	fbxa-167	C31C9.3	n/a	chrII 13,642,551	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
23	W06A11.2	W06A11.2	n/a	chrII 4,060,321
24	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
25	ZK822.1	ZK822.1	n/a	chrIV 11,920,082	contains similarity to Homo sapiens myosin, heavy polypeptide 7B, cardiac muscle, beta; ENSEMBL:ENSP00000262873
26	sri-24	C41G6.11	n/a	chrV 15,212,913	C. elegans SRI-24 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	K07E8.10	K07E8.10	n/a	chrII 666,102
28	cut-4	E04D5.3	n/a	chrII 10,437,905	C. elegans CUT-4 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001507 (Endoglin/CD105 antigen)
29	srx-65	K07C6.8	n/a	chrV 3,922,434	C. elegans SRX-65 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	R13.3	R13.3	n/a	chrIV 10,830,875	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
31	C30H6.5	C30H6.5	n/a	chrIV 17,373,653	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN)
32	C06E7.4	C06E7.4	n/a	chrIV 5,855,392	contains similarity to Human cytomegalovirus Protein UL53 (Protein HFRF2).; SW:P16794
33	C49D10.4	C49D10.4	n/a	chrII 3,871,448	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
34	H39E20.1	H39E20.1	n/a	chrX 1,396,448
35	bath-24	B0047.3	n/a	chrII 2,045,144	C. elegans BATH-24 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
36	K03H1.11	K03H1.11	n/a	chrIII 9,951,334	contains similarity to Pfam domain PF00646 (F-box domain)
37	C30B5.6	C30B5.6	n/a	chrII 6,220,573
38	F32H5.1	F32H5.1	n/a	chrV 13,357,051	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
39	C29F9.12	C29F9.12	n/a	chrIII 121,876
40	M18.3	M18.3	n/a	chrIV 12,107,094	contains similarity to Pfam domain PF00733 Asparagine synthase contains similarity to Interpro domains IPR001962 (Asparagine synthase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
41	srw-2	T03D3.3	n/a	chrV 2,831,793	C. elegans SRW-2 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	F55G1.6	F55G1.6	n/a	chrIV 7,474,219	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR011016 (Zinc finger, variant RING-type)
43	srh-265	T06E6.9	n/a	chrV 15,416,909	C. elegans SRH-265 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
44	srt-22	ZK1037.3	n/a	chrV 15,315,273	C. elegans SRT-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
45	F45C12.16	F45C12.16	n/a	chrII 1,737,908	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
46	cyp-25A4	C36A4.6	n/a	chrIII 3,850,968	C. elegans CYP-25A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
47	srh-231	C03G6.11	n/a	chrV 7,351,540	C. elegans SRH-231 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003944 (Protease-activated receptor 4)
48	str-25	F44G3.11	n/a	chrV 16,116,262	C. elegans STR-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	snx-3	W06D4.5	n/a	chrI 9,064,058	C. elegans SNX-3 protein; contains similarity to Pfam domain PF00787 PX domain contains similarity to Interpro domain IPR001683 (Phox-like)
50	fbxb-5	F45C12.14	n/a	chrII 1,721,873	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.