UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cdh-8	F18F11.3	0	chrIV 351,612	cdh-8 encodes a cadherin that may be nematode specific; CDH-8 is predicted to function as a membrane protein that plays a role in cell adhesion and/or morphogenesis, but as loss of cdh-8 activity via mutation or large-scale RNAi experiments results in no obvious abnormalities, the precise role of cdh-8 in C. elegans development and/or behavior is not yet known.
2	R07B1.9	R07B1.9	n/a	chrX 9,879,387	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g15170).; TR:Q8L731
3	srsx-27	C51E3.2	n/a	chrV 10,151,415	C. elegans SRSX-27 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
4	B0250.8	B0250.8	n/a	chrV 20,465,482	contains similarity to Mycoplasma mycoides FtsY protein.; TR:O05289
5	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
6	Y56A3A.11	Y56A3A.11	n/a	chrIII 11,896,407	contains similarity to Pfam domain PF01974 tRNA intron endonuclease, catalytic C-terminal domain contains similarity to Interpro domains IPR006677 (tRNA intron endonuclease, catalytic domain-like), IPR011856 (Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)
7	C49H3.9	C49H3.9	n/a	chrIV 7,908,266	contains similarity to Pfam domain PF07967 C3HC zinc finger-like contains similarity to Interpro domain IPR012935 (Zinc finger, C3HC-like)
8	tza-2	K03E6.4	n/a	chrX 1,067,909	C. elegans TZA-2 protein; contains similarity to Pfam domain PF07162 B9 protein contains similarity to Interpro domain IPR010796 (B9)
9	sor-3	C04E7.2	n/a	chrX 355,777	sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus.
10	C03B1.9	C03B1.9	n/a	chrX 6,346,694
11	C09G9.3	C09G9.3	n/a	chrIV 8,871,534	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
12	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
13	F55F8.3	F55F8.3	n/a	chrI 5,651,700	contains similarity to Pfam domains PF04047 (Periodic tryptophan protein 2 WD repeat associated presumed domain) , PF00400 (WD domain, G-beta repeat) (5)contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR017441 (Protein kinase ATP binding, conserved site), IPR011046 (WD40 repeat-like), IPR007190 (Periodic tryptophan protein-associated region), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
14	ceh-34	C10G8.6	n/a	chrV 5,317,530	ceh-34 encodes a homeodomain protein, homologous to human SIX2 (OMIM:604994), that is expressed very weakly in the pharynxes of late embryos and early larvae; it has no known function.
15	W04C9.6	W04C9.6	n/a	chrI 485,237	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
16	W02B8.1	W02B8.1	n/a	chrII 13,900,226
17	sas-5	F35B12.5	n/a	chrV 11,611,859	sas-5 encodes a coiled-coil protein whose activity is required, paternally, maternally, and in a dose-dependent manner, for daughter centriole formation; SAS-5 localizes to both the cytoplasm and to centrioles, and photobleaching experiments reveal rapid SAS-5 cycling between these two cellular components throughout the cell cycle; SAS-5 localization to centrioles depends upon the ZYG-1 kinase and the SAS-6 coiled-coil protein, two proteins also required for centriole duplication; in turn, SAS-5 activity is required for SAS-6 centriolar localization, as SAS-6 fails to localize properly in sas-5 mutant embryos.
18	igcm-2	SSSD1.1	n/a	chrX 6,382,121	igcm-2 encodes a protein containing immunoglobulin and fibronectin repeats; igcm-2 promoter::gfp fusions are expressed in the PVT interneuron, in some head neurons, and in the pharynx and intestine.
19	C56E6.4	C56E6.4	n/a	chrII 6,527,652	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
20	K08C9.5	K08C9.5	n/a	chrI 11,483,971	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	B0250.2	B0250.2	n/a	chrV 20,473,310	contains similarity to Drosophila erecta Female-specific transformer protein.; SW:TRSF_DROER
22	T02H6.3	T02H6.3	n/a	chrII 692,115
23	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
24	E04A4.6	E04A4.6	n/a	chrIV 4,746,804	contains similarity to Homo sapiens Isoform 5 of Tectonic-1 precursor; ENSEMBL:ENSP00000380771
25	srh-47	T03F7.4	n/a	chrV 11,299,983	C. elegans SRH-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006069 (ATPase, P-type cation exchange, alpha subunit)
26	F22F7.6	F22F7.6	n/a	chrV 2,116,951	contains similarity to Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; ENSEMBL:ENSP00000309096
27	R10D12.7	R10D12.7	n/a	chrV 13,950,209	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
28	lin-8	B0454.1	n/a	chrII 3,058,509	lin-8 is a class A synthetic multivulva (synMuv) gene that functions redundantly with class B synMuv genes to negatively regulate Ras-mediated signaling during vulval induction.
29	F35E2.2	F35E2.2	n/a	chrI 11,737,158	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	phat-1	C46H11.8	n/a	chrI 5,045,010	C. elegans PHAT-1 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
31	Y116A8C.15	Y116A8C.15	n/a	chrIV 16,996,337	contains similarity to Homo sapiens similar to KIAA1357 protein; ENSEMBL:ENSP00000258005
32	Y116A8C.9	Y116A8C.9	n/a	chrIV 16,943,608	contains similarity to Danio rerio Transmembrane protein 185-like.; SW:Q7SYC7
33	lact-7	C40H5.4	n/a	chrX 11,762,779	lact-7 encodes a beta-lactamase domain-containing protein.
34	F53E10.3	F53E10.3	n/a	chrV 2,606,470
35	C02B8.6	C02B8.6	n/a	chrX 8,134,694	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
36	sru-19	T04A11.8	n/a	chrIV 12,499,445	C. elegans SRU-19 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
37	B0286.1	B0286.1	n/a	chrII 4,382,555	contains similarity to Homo sapiens Ubiquitin carboxyl-terminal hydrolase 8; ENSEMBL:ENSP00000302239
38	F29F11.3	F29F11.3	n/a	chrV 10,658,900	contains similarity to Drosophila melanogaster Flybase gene name is CG10189-PA;; FLYBASE:CG10189
39	srbc-18	C45H4.6	n/a	chrV 2,169,987	C. elegans SRBC-18 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
40	C11G6.2	C11G6.2	n/a	chrX 16,329,525	contains similarity to Interpro domain IPR003593 (AAA+ ATPase, core)
41	ZC373.5	ZC373.5	n/a	chrX 10,073,415	contains similarity to Pfam domain PF00596 Class II Aldolase and Adducin N-terminal domain contains similarity to Interpro domain IPR001303 (Class II aldolase/adducin, N-terminal)
42	str-148	M01D1.1	n/a	chrII 1,047,396	C. elegans STR-148 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
43	T15B7.12	T15B7.12	n/a	chrV 6,818,884	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
44	rab-33	F43D9.2	n/a	chrIII 10,501,953	C. elegans RAB-33 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR000694 (Proline-rich region), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
45	grl-1	C24G6.7	n/a	chrV 5,532,342	grl-1 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; GRL-1 is expressed in intestine, neurons, and larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
46	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
47	C03B1.10	C03B1.10	n/a	chrX 6,357,809	contains similarity to Homo sapiens cDNA FLJ42885 fis, clone BRHIP3007586; HI:HIT000044748
48	C27B7.7	C27B7.7	n/a	chrIV 8,911,257	contains similarity to Pfam domains PF00047 (Immunoglobulin domain) , PF00041 (Fibronectin type III domain) (6)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR003962 (Fibronectin, type III subdomain), IPR013151 (Immunoglobulin)
49	hpl-1	K08H2.6	n/a	chrX 13,246,140	hpl-1 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; loss of hpl-1 activity alone results in no obvious defects, but animals doubly mutant for hpl-1 and hpl-2 have defects in larval, somatic gonad and germline development; in addition, hpl-1 functions redundantly with hpl-2 and lin-13 in vulval development; rescuing HPL-1::GFP fusion proteins are expressed in nuclei throughout the life cycle, beginning at approximately the 50-cell stage of embryogenesis and continuing through larval and adult stages; expression is observed in most, but not all, cells and is particularly strong in head and tail hypodermal and neuronal nuclei; in nuclei, HPL-1::GFP is seen in foci that do not significantly overlap with those of HPL-2.
50	Y51A2B.2	Y51A2B.2	n/a	chrV 18,375,467	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domain IPR006874 (Protein of unknown function DUF621)