UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F18A11.3	F18A11.3	6.999999999999999e-19	chrII 13,036,522	contains similarity to Candida albicans Multidrug resistance protein CDR2.; SW:CDR2_CANAL
2	clec-92	Y52B11A.5	n/a	chrI 11,016,484	C. elegans CLEC-92 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
3	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
4	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
5	R03H4.1	R03H4.1	n/a	chrV 9,018,100	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
6	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
7	ZK1053.3	ZK1053.3	n/a	chrI 13,248,255	contains similarity to Interpro domain IPR011008 (Dimeric alpha-beta barrel)
8	crb-1	F11C7.4	n/a	chrX 17,408,117	crb-1 encodes a homolog of Drosophila CRUMBS that affects dauer formation and feeding behavior; CRB-1 can bind cyclic AMP-response element (CRE) sites and be phosphorylated by PKA in vitro, and is expressed immediately apical to the zonula adherens in embryos and then ubiquitously later during development and in adults; CRB-1 is homologous to human CRB1 (OMIM:604210, mutated in retinitis pigmentosa 12 or Leber congenital amaurosis).
9	clec-19	F36H5.6	n/a	chrII 1,744,331	C. elegans CLEC-19 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	T15B7.8	T15B7.8	n/a	chrV 6,822,465	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
11	Y43F8C.13	Y43F8C.13	n/a	chrV 19,691,051	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
12	rps-8	F42C5.8	n/a	chrIV 7,313,435	rps-8 encodes a small ribosomal subunit S8 protein; by homology, RPS-8 is predicted to function in protein biosynthesis; in C. elegans, RPS-8 activity is required for germline development and the overall health of the animal.
13	srx-23	F31F4.2	n/a	chrV 683,114	C. elegans SRX-23 protein ;
14	F40E3.2	F40E3.2	n/a	chrI 2,643,222
15	ZK512.2	ZK512.2	n/a	chrIII 9,143,217	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
16	F22E5.12	F22E5.12	n/a	chrII 2,646,586	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
17	W10D9.2	W10D9.2	n/a	chrII 451,150	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	C15C8.5	C15C8.5	n/a	chrV 12,749,106	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
19	C07A4.3	C07A4.3	n/a	chrX 10,175,118	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
20	C32B5.7	C32B5.7	n/a	chrII 962,400	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
21	R07B1.8	R07B1.8	n/a	chrX 9,871,676
22	tmbi-4	B0563.4	n/a	chrX 9,155,606	C. elegans TMBI-4 protein; contains similarity to Pfam domain PF01027 Uncharacterised protein family UPF0005 contains similarity to Interpro domain IPR006214 (Protein of unknown function UPF0005)
23	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
24	glb-10	C29F5.7	n/a	chrII 6,308,800	glb-10 encodes a globin; glb-10 is expressed in pharynx, intestine, vulval muscle, and many neurons, with at least some subcellular localization to synapses; however, glb-10 has no obvious function in mass RNAi assays.
25	Y49F6C.2	Y49F6C.2	n/a	chrII 3,379,231
26	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
27	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
28	math-5	C16C4.10	n/a	chrII 1,882,210	C. elegans MATH-5 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
29	Y62H9A.10	Y62H9A.10	n/a	chrX 11,901,221	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	F23H11.6	F23H11.6	n/a	chrIII 914,468
31	T14B4.9	T14B4.9	n/a	chrII 6,731,934	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
32	W03F11.5	W03F11.5	n/a	chrI 2,217,759	n/a
33	F28B1.5	F28B1.5	n/a	chrV 17,058,496
34	F13D2.4	F13D2.4	n/a	chrX 11,188,488	contains similarity to Homo sapiens Isoform 3 of CD109 antigen precursor; HI:HIT000020743
35	F52C9.5	F52C9.5	n/a	chrIII 5,304,230	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR003609 (Apple-like), IPR003014 (N/apple PAN)
36	srh-37	R11G11.9	n/a	chrV 511,858	C. elegans SRH-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	R06B10.2	R06B10.2	n/a	chrIII 975,911	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
38	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
39	C45G7.4	C45G7.4	n/a	chrIV 2,434,709	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
40	Y39A1A.17	Y39A1A.17	n/a	chrIII 10,688,996	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
41	Y49G5B.1	Y49G5B.1	n/a	chrV 5,228,330	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
42	clec-34	T25E12.8	n/a	chrV 16,736,555	C. elegans CLEC-34 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
43	srh-18	C50B6.5	n/a	chrV 13,319,254	C. elegans SRH-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	R07B7.8	R07B7.8	n/a	chrV 12,082,679	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
45	K01A12.3	K01A12.3	n/a	chrX 8,622,819	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
46	ZK669.2	ZK669.2	n/a	chrII 7,937,580	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
47	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	unc-120	D1081.2	n/a	chrI 8,461,612	unc-120 encodes a member of the MADS-box family of transcription factors that is most closely related to Drosophila blistered and the vertebrate serum response factors (SRFs); UNC-120 is required for locomotion and muscle development and for formation of the normal number of muscle A and I bands; UNC-120 is also required for maintaining wild-type expression levels of the muscle components actin and myosin; UNC-120 is first expressed in the early embryo in body wall muscle precursors and later is expressed in both body wall and vulval muscles.
49	K01A11.2	K01A11.2	n/a	chrIII 3,426,861	contains similarity to Xenopus laevis LOC495955 protein.; TR:Q5PQ79
50	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.