UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-33	F17E9.13	9.999999999999999e-43	chrIV 8,335,508	his-33 encodes an H2A histone; by homology, HIS-33 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-33 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
2	T06D8.10	T06D8.10	n/a	chrII 11,244,135	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR001007 (von Willebrand factor, type C)
3	M195.2	M195.2	n/a	chrII 8,362,076	contains similarity to Pfam domain PF02363 Cysteine rich repeat
4	drr-1	F45H10.4	n/a	chrII 13,495,384	C. elegans DRR-1 protein; contains similarity to Interpro domain IPR008253 (Marvel)
5	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
6	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
7	his-61	F55G1.10	9.999999999999999e-43	chrIV 7,485,966	his-61 encodes an H2A histone.
8	R10E4.9	R10E4.9	n/a	chrIII 4,302,001	contains similarity to Pfam domain PF04387 Protein tyrosine phosphatase-like protein, PTPLA contains similarity to Interpro domain IPR007482 (Protein-tyrosine phosphatase-like, PTPLA)
9	nas-38	F57C12.1	n/a	chrX 560,901	C. elegans NAS-38 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00090 (Thrombospondin type 1 domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
10	his-57	F54E12.5	9.999999999999999e-43	chrIV 11,340,574	his-57 encodes an H2A histone.
11	K01D12.5	K01D12.5	n/a	chrV 12,398,255	contains similarity to Interpro domain IPR003980 (Histamine H3 receptor)
12	his-43	F08G2.2	9.999999999999999e-43	chrII 13,827,426	his-43 encodes an H2A histone.
13	his-30	F35H10.1	9.999999999999999e-43	chrIV 8,331,839	his-30 encodes an H2A histone; by homology, HIS-30 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-30 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
14	C34F6.8	C34F6.8	n/a	chrX 11,216,944	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
15	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
16	abu-2	F19G12.7	n/a	chrX 1,409,740	abu-2 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-2 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-2 may help protect the organism from damage by improperly folded nascent protein.
17	K09H11.7	K09H11.7	n/a	chrV 5,752,981	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR006349 (2-phosphoglycolate phosphatase, eukaryotic), IPR005834 (Haloacid dehalogenase-like hydrolase)
18	C42D4.2	C42D4.2	n/a	chrIV 7,181,781	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
19	T17H7.7	T17H7.7	n/a	chrIII 756,721
20	K07E3.2	K07E3.2	n/a	chrX 8,105,875
21	T01D1.3	T01D1.3	n/a	chrII 175,055
22	C36B7.6	C36B7.6	n/a	chrX 7,098,999	contains similarity to Pfam domain PF05602 Cleft lip and palate transmembrane protein 1 (CLPTM1) contains similarity to Interpro domain IPR008429 (Cleft lip and palate transmembrane 1)
23	F47G9.3	F47G9.3	n/a	chrV 11,315,117	contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00024 (PAN domain) (2)contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
24	F17C11.1	F17C11.1	n/a	chrV 10,942,089	contains similarity to Methanosarcina mazei Conserved protein.; TR:Q8PT55
25	T24C12.4	T24C12.4	n/a	chrX 2,204,550
26	T07G12.3	T07G12.3	n/a	chrIV 10,535,145	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
27	K09C4.10	K09C4.10	n/a	chrX 3,278,116	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q7A362
28	srz-64	Y57G7A.7	n/a	chrII 1,291,002	C. elegans SRZ-64 protein ;
29	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
30	C27A2.5	C27A2.5	n/a	chrII 5,069,164	contains similarity to Interpro domains IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR006081 (Alpha defensin), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
31	cnx-1	ZK632.6	n/a	chrIII 9,815,658	cnx-1 encodes the C. elegans ortholog of calnexin, a type I Ca2+-binding integral membrane protein of the endoplasmic reticulum (ER); CNX-1 binds calcium and is predicted to function as a molecular chaperone required for glycoprotein folding and maturation as well as regulation of intracellular calcium homeostasis; in C. elegans, cnx-1 activity is required at 25 degrees C for wild-type levels of fertility and normal embryonic and larval development; cnx-1 activity is also required for maintaining viability in response to ER stress; in addition, cnx-1(RNAi) can suppress necrotic-like cell death induced by hyperactivated MEC-4 and DEG-1 ion channels, suggesting that CNX-1 also plays a role in regulating necrotic cell death; CNX-1 expression is first detected ubiquitously in the early embryo, with expression then becoming restricted to embryonic head and tail regions; post-embryonic expression is seen in the excretory cell, head and tail neurons, spermatheca, intestine, germ cells, and spicules in the male tail; antibody staining of early embryos indicates that CNX-1 localizes to the endoplasmic reticulum; in regulating reproduction at 25 degrees C, cnx-1 functions redundantly with crt-1, which encodes calreticulin, an additional Ca2+-binding ER chaperone protein.
32	D1054.1	D1054.1	n/a	chrV 10,769,166	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
33	F13H10.5	F13H10.5	n/a	chrIV 10,992,558	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
34	K09H11.1	K09H11.1	n/a	chrV 5,749,898	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF01636 (Phosphotransferase enzyme family) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR011009 (Protein kinase-like), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR000169 (Peptidase, cysteine peptidase active site), IPR005834 (Haloacid dehalogenase-like hydrolase), IPR008266 (Tyrosine protein kinase, active site), IPR002575 (Aminoglycoside phosphotransferase)
35	R03A10.3	R03A10.3	n/a	chrX 15,438,160	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR011037 (Pyruvate kinase, beta-barrel-like), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
36	C49A9.3	C49A9.3	n/a	chrIV 6,223,512	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domains IPR000711 (ATPase, F1 complex, OSCP/delta subunit), IPR004987 (Protein of unknown function DUF272)
37	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
38	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
39	amx-3	F25C8.2	n/a	chrV 20,896,026	C. elegans AMX-3 protein; contains similarity to Pfam domain PF01593 Flavin containing amine oxidoreductase contains similarity to Interpro domains IPR000759 (Adrenodoxin reductase), IPR001613 (Flavin-containing amine oxidase), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding)
40	C08F11.7	C08F11.7	n/a	chrIV 13,637,874	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR002398 (Peptidase C14, caspase precursor p45)
41	ZK899.3	ZK899.3	n/a	chrX 9,454,242	contains similarity to Homo sapiens C10ORF6; ENSEMBL:ENSP00000238961
42	M02G9.1	M02G9.1	n/a	chrII 10,330,867	contains similarity to Pfam domain PF02363 Cysteine rich repeat contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR015333 (Pollen allergen ole e 6)
43	ptr-11	F56C11.2	n/a	chrI 163,495	ptr-11 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-11 is required for normal growth to full size, locomotion, and vulval morphogenesis.
44	R07B7.10	R07B7.10	n/a	chrV 12,085,340	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
45	C33G3.4	C33G3.4	n/a	chrX 14,073,660	C33G3.4 is orthologous to the human gene BETA-MANNOSIDASE (MANBA; OMIM:248510), which when mutated leads to disease.
46	ulp-2	Y38A8.3	n/a	chrII 4,957,746	C. elegans ULP-2 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
47	K02G10.5	K02G10.5	n/a	chrX 4,689,524	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
48	ech-8	F01G10.2	n/a	chrIV 10,237,849	C. elegans ECH-8 protein; contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR013328 (Dehydrogenase, multihelical), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR016040 (NAD(P)-binding)
49	lact-8	Y42A5A.2	n/a	chrV 11,092,342	lact-8 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
50	K10D11.3	K10D11.3	n/a	chrIV 12,984,093	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)