UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F16F9.4	F16F9.4	0	chrX 8,461,517	contains similarity to Pfam domain PF07859 alpha/beta hydrolase fold contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR017157 (Arylacetamide deacetylase), IPR013094 (Alpha/beta hydrolase fold-3)
2	K09C4.5	K09C4.5	n/a	chrX 3,284,155	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
3	C50D2.8	C50D2.8	n/a	chrII 97,034	contains similarity to Pfam domain PF03194 LUC7 N_terminus contains similarity to Interpro domain IPR004882 (LUC7 related)
4	F20D6.11	F20D6.11	n/a	chrV 8,197,919	F20D6.11 encodes a putative flavin-adenine dinucleotide (FAD)-binding oxidoreductase orthologous to human AIFM3 (AIFL), and paralogous to WAH-1 and mammalian PDCD8 (AIF; OMIM:300169, mutated in Harlequin mice); F20D6.11 is expressed in pharynx, anal depressor and body wall muscles, the reproductive system (including spermatheca), and unidentified tail cells; given its orthology to AIFM3, F20D6.11 may promote apoptosis; however, F20D6.11 has no obvious function in mass RNAi assays.
5	srt-69	B0238.8	n/a	chrV 5,264,800	C. elegans SRT-69 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	ZC504.3	ZC504.3	n/a	chrX 10,418,158	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
7	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
8	nfyc-1	F23F1.1	n/a	chrII 44,432	C. elegans NFYC-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
9	F28C1.1	F28C1.1	n/a	chrV 12,452,041	contains similarity to Drosophila melanogaster Flybase gene name is CG6695-PA;; FLYBASE:CG6695
10	clh-6	R07B7.1	n/a	chrV 12,061,778	clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation.
11	rad-26	C27B7.4	n/a	chrIV 8,897,727	C. elegans RAD-26 protein; contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR000694 (Proline-rich region), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal), IPR000276 (GPCR, rhodopsin-like)
12	C32D5.10	C32D5.10	n/a	chrII 6,350,550	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
13	F11E6.8	F11E6.8	n/a	chrIV 17,447,304	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
14	figl-1	F32D1.1	n/a	chrV 4,343,730	F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays.
15	Y54E5A.6	Y54E5A.6	n/a	chrI 14,709,596	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00035 (Double-stranded RNA binding motif) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like), IPR000632 (Yeast Mrs6p protein), IPR001269 (Dihydrouridine synthase, DuS)
16	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
17	srd-53	F13G3.2	n/a	chrI 7,294,860	C. elegans SRD-53 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	F13E6.2	F13E6.2	n/a	chrX 10,671,215	contains similarity to Pfam domain PF05186 Dpy-30 motif contains similarity to Interpro domains IPR000850 (Adenylate kinase), IPR007858 (Dpy-30), IPR011769 (Adenylate/cytidine kinase, N-terminal)
19	gtl-1	C05C12.3	n/a	chrIV 11,254,145	gtl-1 encodes a TRPM subfamily member of the TRP channel family that affects the periodicity of the defecation cycle in combination with gon-2; expression includes the intestine.
20	T07F10.5	T07F10.5	n/a	chrV 12,866,209	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR002018 (Carboxylesterase, type B)
21	ctg-1	H06O01.3	n/a	chrI 7,007,341	C. elegans CTG-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
22	math-19	C40D2.1	n/a	chrII 1,999,260	C. elegans MATH-19 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	C06E1.3	C06E1.3	n/a	chrIII 8,582,414	contains similarity to Drosophila melanogaster Flybase gene name is mol-PD;; FLYBASE:CG4482
24	tap-1	C44H4.5	n/a	chrX 14,590,650	C. elegans TAP-1 protein; contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
25	R03A10.3	R03A10.3	n/a	chrX 15,438,160	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR011037 (Pyruvate kinase, beta-barrel-like), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
26	cacn-1	W03H9.4	n/a	chrII 14,137,700	cacn-1 encodes an ortholog of Drosophila CACTIN and human C19orf29 that is required for normal distal tip cell migration, embryonic viability, fertility, locomotion, vulval morphogenesis, and normally rapid growth; like CACTIN, CACN-1 contains predicted coiled-coil domains, but otherwise lacks recognizable similarity to known proteins.
27	K02G10.5	K02G10.5	n/a	chrX 4,689,524	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
28	fbxa-84	T09F5.11	n/a	chrV 15,183,260	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
30	F22G12.3	F22G12.3	n/a	chrI 13,153,129	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
31	Y40B1B.8	Y40B1B.8	n/a	chrI 13,431,748	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domain IPR001993 (Mitochondrial substrate carrier)
32	F13E6.5	F13E6.5	n/a	chrX 10,696,500	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR016118 (Phosphatidic acid phosphatase/chloroperoxidase, N-terminal)
33	tag-131	H38K22.3	n/a	chrIII 4,318,987	C. elegans TAG-131 protein; contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
34	dpy-1	M01E10.2	n/a	chrIII 2,041,006	dpy-1 encodes a collagen that affects body length and alae formation; site of action localized to the hyp7 syncytium, based on mosaic analysis.
35	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
36	B0019.2	B0019.2	n/a	chrI 12,777,941	contains similarity to Pfam domains PF04435 (Domain of unknown function (DUF545)) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR006570 (SPK), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR009057 (Homeodomain-like)
37	vhl-1	F08G12.4	n/a	chrX 11,307,692	vhl-1 is orthologous to the mammalian tumor suppressor gene Von Hippel-Landau syndrome (VHL; OMIM:193300), which is part of a ubiquitylation complex targetting proteins for proteasomal degradation.
38	Y39A1A.6	Y39A1A.6	n/a	chrIII 10,616,526	contains similarity to Interpro domains IPR005727 (Ribosomal protein L22, bacterial-type), IPR001063 (Ribosomal protein L22/L17)
39	ubc-20	F40G9.3	n/a	chrIII 189,890	C. elegans UBC-20 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR009060 (UBA-like), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
40	F58G1.6	F58G1.6	n/a	chrII 12,941,277	contains similarity to Pfam domain PF02752 Arrestin (or S-antigen), C-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal)
41	nas-36	C26C6.3	n/a	chrI 7,529,499	nas-36 encodes an astacin-like protease; nas-36 activity is required for molting; a nas-36::gfp reporter is expressed in hypodermal cells.
42	Y49E10.18	Y49E10.18	n/a	chrIII 12,444,259	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
43	F44E2.3	F44E2.3	n/a	chrIII 8,828,256	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	dnc-2	C28H8.12	n/a	chrIII 5,925,025	dnc-2 encodes a member of the dynamitin family that affects spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration.
45	set-16	T12D8.1	n/a	chrIII 13,650,157	C. elegans SET-16 protein ;
46	F08G12.1	F08G12.1	n/a	chrX 11,303,901	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
47	K04G11.3	K04G11.3	n/a	chrX 14,346,393	contains similarity to Pfam domain PF07547 RSD-2 N-terminal domain contains similarity to Interpro domain IPR011508 (RSD-2, N-terminal)
48	elo-3	D2024.3	n/a	chrIV 7,238,796	The elo-3 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-3 may be required for normally rapid growth.
49	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
50	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.