UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F15A4.10	F15A4.10	4e-40	chrII 12,484,765	contains similarity to Saccharomyces cerevisiae Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate; SGD:YOR195W
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F14F9.4	F14F9.4	n/a	chrV 5,134,905	contains similarity to Interpro domain IPR002867 (Zinc finger, C6HC-type)
4	C44B9.3	C44B9.3	n/a	chrIII 10,879,120	contains similarity to Trypanosoma cruzi Mucin-like protein.; TR:O61047
5	B0334.4	B0334.4	n/a	chrII 11,496,096	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
6	T28C6.3	T28C6.3	n/a	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
7	T24C2.2	T24C2.2	n/a	chrX 14,546,208	contains similarity to Fusobacterium nucleatum Hypothetical protein FN0465.; TR:Q8RG53
8	R07C3.5	R07C3.5	n/a	chrII 931,761
9	sdz-9	F08D12.10	n/a	chrII 2,773,000	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
10	C50F4.4	C50F4.4	n/a	chrV 9,537,163	contains similarity to Streptomyces coelicolor Hypothetical protein SCO3733.; TR:Q9L0X1
11	F52D10.2	F52D10.2	n/a	chrX 11,590,643	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
12	C48B6.9	C48B6.9	n/a	chrI 6,924,938	contains similarity to Interpro domain IPR000366 (Fungal pheromone mating factor STE2 GPCR)
13	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
14	fbxb-62	F55C9.8	n/a	chrV 19,301,505	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
15	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
16	bath-9	Y49F6C.3	n/a	chrII 3,377,880	C. elegans BATH-9 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR010916 (TonB box, conserved site), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
17	C08F1.6	C08F1.6	n/a	chrII 1,787,707
18	F31D5.6	F31D5.6	n/a	chrII 4,211,553	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
19	T24E12.1	T24E12.1	n/a	chrII 3,786,852	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
20	pup-3	F59A3.9	n/a	chrI 5,532,199	pup-3 encodes a template-independent poly(U) polymerase with 3'' end RNA substrates, distantly similar to human ZCCHC6 and ZCCHC11; PUP-3 is paralogous to the GLD-2 family of poly(A) polymerases; PUP-3 has no obvious function in mass RNAi assays.
21	F23D12.2	F23D12.2	n/a	chrX 14,418,796	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	T11F8.1	T11F8.1	n/a	chrIV 5,480,072
24	T05D4.2	T05D4.2	n/a	chrIII 13,562,369	contains similarity to Mus musculus Similar to SPEER 2.; TR:Q80ZP2
25	C13F10.2	C13F10.2	n/a	chrV 7,221,750	contains similarity to Drosophila melanogaster Flybase gene name is CG10681-PA;; FLYBASE:CG10681
26	Y57G11B.1	Y57G11B.1	n/a	chrIV 14,550,857	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
27	F27C1.4	F27C1.4	n/a	chrI 5,423,026
28	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
29	F18C12.3	F18C12.3	n/a	chrI 8,097,075	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54H40
30	C49C3.6	C49C3.6	n/a	chrIV 17,331,938	contains similarity to Saccharomyces cerevisiae a homologue of BUL1; SGD:YML111W
31	F58E1.12	F58E1.12	n/a	chrII 1,693,958
32	fbxb-57	F55C9.4	n/a	chrV 19,289,333	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
33	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
34	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
35	fbxb-67	F49B2.2	n/a	chrI 14,297,764	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
37	fbxb-103	F53C3.2	n/a	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	C17H1.7	C17H1.7	n/a	chrI 13,137,541	contains similarity to Plasmodium reichenowi Reticulocyte binding-like protein 2b.; TR:Q6YA79
39	F10A3.1	F10A3.1	n/a	chrV 16,140,754	F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
40	lgg-3	B0336.8	n/a	chrIII 5,697,730	lgg-3 encodes a hydrophilic protein that is orthologous to Saccharomyces cerevisiae autophagy protein Apg12p; by homology, LGG-3 is predicted to function as a modifier protein required for a protein conjugation system essential for autophagy; in the context of this conjugation system, LGG-3 is predicted to interact with Apg7p and Apg5p homologs (encoded by M7.5 and Y71G12B.12a, respectively) to effect bulk degradation of cytoplasmic components under conditions of starvation or cellular remodeling; free LGG-3 is predicted to localize to the cytoplasm, while LGG-3 conjugated to the Apg5p homolog is predicted to associate with membrane compartments; loss of lgg-3 activity via large-scale RNAi screens results in no obvious developmental or behavioral abnormalities.
41	F19B10.2	F19B10.2	n/a	chrII 3,676,170
42	K09E3.6	K09E3.6	n/a	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
43	C02B8.2	C02B8.2	n/a	chrX 8,144,673
44	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
45	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
46	Y106G6H.9	Y106G6H.9	n/a	chrI 10,455,014	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
47	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
48	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
49	srd-18	F53F1.10	n/a	chrV 13,426,143	C. elegans SRD-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
50	bath-36	Y75B12B.4	n/a	chrV 15,189,546	C. elegans BATH-36 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)