UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F14F9.2	F14F9.2	3e-132	chrV 5,145,296	contains similarity to Homo sapiens Acidic repeat-containing protein; ENSEMBL:ENSP00000362799
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	fbxa-144	F44G3.8	n/a	chrV 16,132,206	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
5	C14A11.2	C14A11.2	n/a	chrX 2,803,965
6	K05C4.7	K05C4.7	n/a	chrI 14,738,206	contains similarity to Interpro domains IPR016617 (Uncharacterised conserved protein UCP013899, metal binding), IPR016024 (Armadillo-type fold)
7	daf-18	T07A9.6	n/a	chrIV 422,580	daf-18 encodes a lipid phosphatase homologous to the human PTEN tumor suppresor (OMIM:601728, mutated in Cowden disease and several cancers); DAF-18 negatively regulates insulin-like signaling mediated by DAF-2/IR and AGE-1/PI3K and thus plays a role in metabolism, development, and longevity; based on sequence and genetic analysis, DAF-18 is predicted to dephosphorylate AGE-1-generated PIP3 in order to limit activation of the downstream AKT-1 and AKT-2 kinases that negatively regulate DAF-16.
8	cyb-1	ZC168.4	n/a	chrIV 10,736,076	cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage.
9	F23A7.4	F23A7.4	n/a	chrX 16,212,627	contains similarity to Mus musculus MKIAA0554 protein (Fragment).; TR:Q80TY0
10	F14F7.5	F14F7.5	n/a	chrIII 13,033,511	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
11	D1081.6	D1081.6	n/a	chrI 8,485,193	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_0200.; TR:Q98RI9
12	F30A10.3	F30A10.3	n/a	chrI 9,493,712	contains similarity to Pfam domain PF03770 Inositol polyphosphate kinase contains similarity to Interpro domain IPR005522 (Inositol polyphosphate kinase)
13	F18A12.2	F18A12.2	n/a	chrII 3,415,610
14	fbxb-20	ZC204.9	n/a	chrII 1,649,687	fbxb-20 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-20 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
15	R07C3.5	R07C3.5	n/a	chrII 931,761
16	F14F9.4	F14F9.4	n/a	chrV 5,134,905	contains similarity to Interpro domain IPR002867 (Zinc finger, C6HC-type)
17	fbxb-11	F45C12.5	n/a	chrII 1,725,771	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
18	clec-102	F33E2.3	n/a	chrI 12,579,521	C. elegans CLEC-102 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
19	C26C6.6	C26C6.6	n/a	chrI 7,506,305	contains similarity to Pfam domain PF00412 LIM domain contains similarity to Interpro domain IPR001781 (Zinc finger, LIM-type)
20	ZK550.3	ZK550.3	n/a	chrIV 17,252,502	contains similarity to Pfam domain PF01432 Peptidase family M3 contains similarity to Interpro domain IPR001567 (Peptidase M3A and M3B, thimet/oligopeptidase F)
21	fbxb-115	T26H2.2	n/a	chrV 19,239,099	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
22	pup-3	F59A3.9	n/a	chrI 5,532,199	pup-3 encodes a template-independent poly(U) polymerase with 3'' end RNA substrates, distantly similar to human ZCCHC6 and ZCCHC11; PUP-3 is paralogous to the GLD-2 family of poly(A) polymerases; PUP-3 has no obvious function in mass RNAi assays.
23	F18C12.3	F18C12.3	n/a	chrI 8,097,075	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54H40
24	F41E6.7	F41E6.7	n/a	chrV 8,598,409
25	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
26	gnrr-2	C15H11.2	n/a	chrV 14,410,464	C. elegans GNRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like), IPR001817 (Vasopressin receptor)
27	str-81	T26H2.6	n/a	chrV 19,226,172	C. elegans STR-81 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	K10C2.6	K10C2.6	n/a	chrX 6,451,568
29	C17E4.6	C17E4.6	n/a	chrI 9,426,826	contains similarity to Pfam domains PF05764 (YL1 nuclear protein) , PF08265 (YL1 nuclear protein C-terminal domain) contains similarity to Interpro domains IPR013272 (YL1 nuclear, C-terminal), IPR008895 (YL1 nuclear)
30	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
31	srj-37	F48G7.1	n/a	chrV 639,279	C. elegans SRJ-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	F08F8.2	F08F8.2	n/a	chrIII 7,360,724	contains similarity to Pfam domain PF00368 Hydroxymethylglutaryl-coenzyme A reductase contains similarity to Interpro domains IPR004554 (Hydroxymethylglutaryl-CoA reductase, class I, catalytic), IPR009029 (Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding), IPR002202 (Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)
33	ZK218.3	ZK218.3	n/a	chrV 17,098,315	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
34	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
35	F32B5.3	F32B5.3	n/a	chrI 2,693,421	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domains IPR004951 (Protein of unknown function DUF268, Caenorhabditis species), IPR003968 (Potassium channel, voltage dependent, Kv)
36	col-20	F11G11.11	n/a	chrII 4,870,188	col-20 encodes a collagen; its expression pattern and mutant phenotypes are unknown.
37	ZC196.9	ZC196.9	n/a	chrV 8,724,688	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR006874 (Protein of unknown function DUF621)
38	T11F8.4	T11F8.4	n/a	chrIV 5,475,352	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	sri-53	ZC239.10	n/a	chrII 3,201,906	C. elegans SRI-53 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	M01E5.4	M01E5.4	n/a	chrI 13,288,518	contains similarity to Homo sapiens Isoform 1 of UPF0561 protein; ENSEMBL:ENSP00000304410
41	F10E7.6	F10E7.6	n/a	chrII 7,113,277
42	gei-6	C05C8.4	n/a	chrV 7,228,595	C. elegans GEI-6 protein; contains similarity to Interpro domain IPR000694 (Proline-rich region)
43	R05H5.5	R05H5.5	n/a	chrII 10,200,234	contains similarity to Pfam domain PF04161 Arv1-like family contains similarity to Interpro domains IPR007290 (Arv1-like protein), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
44	nhr-214	T07C5.3	n/a	chrX 12,701,293	C. elegans NHR-214 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	gly-17	T15D6.3	n/a	chrI 12,377,779	gly-17 encodes a protein similar to 2/I N-acetylglucosaminyltransferase.
46	W05F2.7	W05F2.7	n/a	chrI 3,357,913	contains similarity to Interpro domain IPR000694 (Proline-rich region)
47	rga-3	K09H11.3	n/a	chrV 5,719,976	rga-3 encodes a GTPase-activating protein (GAP); RNAi experiments predicted to target rga-3 and the related rga-4 gene result in early embryonic defects, specifically defects in cortical contractility, non-muscle myosin NMY-2 distribution, and the relative size of PAR protein domains; in vitro, RGA-3 positively regulates RHO-1 GTPase activity, consistent with genetic studies showing that the rga-3/4(RNAi) phenotype requires RHO-1 activity; in early embryos, a YFP-RGA-3 fusion protein localizes to the cellular cortex and to centrosomes, with cortical localization segregating to the anterior during polarization.
48	fbxb-98	C16C4.6	n/a	chrII 1,863,210	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
49	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)