UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	bath-27	F14D2.1	1.0000000000000001e-175	chrII 3,360,782	C. elegans BATH-27 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
2	cdk-5	T27E9.3	n/a	chrIII 13,465,418	cdk-5 encodes a putative homolog of cyclin dependent kinase 5 that affects pronuclear migration and rotation in one-cell embryos and may affect neuronal development; expressed in neurons.
3	coq-4	T03F1.2	n/a	chrI 3,869,644	coq-4 encodes an ortholog of S. cerevisiae COQ4; while COQ-4 is conserved between eukaryotes and bacteria, its biochemical function is unknown; by orthology, COQ-4 is predicted to peripherally associate with the matrix face of the mitochondrial inner membrane, in a complex with COQ-3 (and perhaps COQ-6), and to be required to maintain a steady-state level of CLK-1/COQ-7 protein; COQ-4 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-4(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans.
4	T04H1.5	T04H1.5	n/a	chrV 12,251,820	contains similarity to Pfam domain PF01585 G-patch domain contains similarity to Interpro domains IPR000467 (D111/G-patch), IPR007087 (Zinc finger, C2H2-type)
5	F49C5.5	F49C5.5	n/a	chrII 12,546,186
6	F25H9.6	F25H9.6	n/a	chrV 13,467,638	contains similarity to Pfam domain PF02441 Flavoprotein contains similarity to Interpro domain IPR003382 (Flavoprotein)
7	T09A5.8	T09A5.8	n/a	chrII 7,856,638	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like), IPR001525 (C-5 cytosine-specific DNA methylase)
8	T12F5.2	T12F5.2	n/a	chrI 3,732,139
9	Y102A5C.2	Y102A5C.2	n/a	chrV 16,919,147	contains similarity to Saccharomyces cerevisiae anti-silencing protein that causes depression of silent loci when overexpressed; SGD:YJL115W
10	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
11	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
12	opt-1	C06G8.2	n/a	chrIV 10,792,535	opt-1 encodes a high-affinity, proton-coupled oligopeptide transporter; when expressed in Xenopus ooctyes, OPT-1 exhibits proton-coupled transport activity for a broad spectrum of peptide substrates; opt-1 mRNA is detected at all stages of development, but is expressed at highest levels in late larval and adult stages; additionally, an opt-1::GFP reporter exhibits expression primarily in vulval, pharyngeal, and anal muscles; as loss of opt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of opt-1 in C. elegans development and/or behavior is not yet known.
13	R09E12.6	R09E12.6	n/a	chrV 767,566	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
14	mut-7	ZK1098.8	n/a	chrIII 9,540,593	mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference.
15	csb-1	F53H4.1	n/a	chrX 15,863,557	csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells.
16	B0361.7	B0361.7	n/a	chrIII 7,284,829	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
17	taf-6.1	W09B6.2	n/a	chrII 1,130,167	C. elegans TAF-6.1 protein; contains similarity to Pfam domains PF07571 (Protein of unknown function (DUF1546)) , PF02969 (TATA box binding protein associated factor (TAF)) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR004823 (TATA box binding protein associated factor (TAF)), IPR011442 (Protein of unknown function DUF1546)
18	ZC168.3	ZC168.3	n/a	chrIV 10,733,704	contains similarity to Homo sapiens Origin recognition complex subunit 5; ENSEMBL:ENSP00000297431
19	zfp-2	F35H8.3	n/a	chrII 9,558,501	zfp-2 encodes a zinc-finger transcription factor; loss of zfp-2 and lin-35/Rb results in almost complete sterility accompanied by defects in somatic gonad development and vulval morphology, as well as polyploidization of somatic cell nuclei; loss of zfp-2 activity by itself reveals that zfp-2 is also required for cosuppression, inhibition of RNAi of some genes, and wild-type levels of expression of a rol-6 extrachromosomal array; a zfp-2::GFP promoter fusion construct is expressed in vulval cells and all somatic gonad structures, such as the spermatheca, sheath cells, uterine cells and distal tip cells (DTCs).
20	K03B4.1	K03B4.1	n/a	chrV 4,690,455
21	M03C11.2	M03C11.2	n/a	chrIII 10,402,129	contains similarity to Pfam domain PF06733 DEAD_2 contains similarity to Interpro domains IPR014013 (Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type), IPR010614 (DEAD2), IPR006554 (Helicase-like, DEXD box c2 type), IPR006555 (Helicase, ATP-dependent, c2 type), IPR014001 (DEAD-like helicase, N-terminal), IPR013020 (DNA helicase (DNA repair), Rad3 type)
22	xpa-1	K07G5.2	n/a	chrI 7,160,236	xpa-1 encodes an ortholog of human XPA, the xeroderma pigmentosum complementation group A protein (OMIM:278700, mutations are associated with sensitivity to ultraviolet light and carcinomata at an early age); by homology, XPA-1 is predicted to function as a DNA-binding protein that is required for nucleotide excision repair of damaged DNA; in C. elegans, loss of xpa-1 activity via mutation or RNA-mediated interference (RNAi) results in increased sensitivity to UV irradiation at all stages of development; xpa-1 mRNA is detected in eggs and mixed stage populations.
23	ZC477.4	ZC477.4	n/a	chrIV 7,098,647
24	sre-9	C17E7.3	n/a	chrV 3,896,569	C. elegans SRE-9 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
25	F36D4.1	F36D4.1	n/a	chrV 9,418,520
26	str-165	F55B12.6	n/a	chrV 13,832,194	C. elegans STR-165 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001358 (Neuropeptide Y2 receptor)
27	M151.2	M151.2	n/a	chrII 3,632,782	contains similarity to Interpro domain IPR000533 (Tropomyosin)
28	ZC412.8	ZC412.8	n/a	chrV 14,879,632	contains similarity to Plasmodium cynomolgi Circumsporozoite protein precursor (CS).; SW:P08675
29	pfn-1	Y18D10A.20	n/a	chrI 12,922,763	C. elegans PFN-1 protein; contains similarity to Pfam domain PF00235 Profilin contains similarity to Interpro domains IPR002097 (Profilin/allergen), IPR005455 (Profilin, plant)
30	gad-1	T05H4.14	n/a	chrV 6,432,396	The gad-1 gene encodes a WD repeat-containing protein that is required maternally for gastrulation initiation during early embryogenesis by regulating the division timing, spindle orientation, and subsequent inward migration of the two gut precusor (E) cells at the 26-cell stage.
31	D1044.6	D1044.6	n/a	chrIII 5,539,373	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
32	F36H12.2	F36H12.2	n/a	chrIV 5,275,375
33	gpa-11	C16A11.1	n/a	chrII 4,254,160	gpa-11 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADL and ASH amphid neurons.
34	M01E5.1	M01E5.1	n/a	chrI 13,275,251	contains similarity to Ichthyophthirius multifiliis Immobilization antigen isoform.; TR:Q9BMH3
35	his-74	W05B10.1	n/a	chrV 12,659,997	C. elegans HIS-74 protein; contains similarity to Pfam domain PF00125 Core histone H2A/H2B/H3/H4 contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold), IPR007125 (Histone core)
36	Y54E2A.4	Y54E2A.4	n/a	chrII 14,754,890	contains similarity to Archaeoglobus fulgidus NADH oxidase (NOXA-3).; TR:O29847
37	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
38	VF39H2L.1	VF39H2L.1	n/a	chrI 8,645,323	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000727 (Target SNARE coiled-coil region)
39	C46A5.5	C46A5.5	n/a	chrIV 7,758,797
40	F02E9.7	F02E9.7	n/a	chrI 8,414,687	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
41	ani-2	K10B2.5	n/a	chrII 6,363,196	ani-2 encodes one of three C. elegans anillins; ANI-2 activity is required in the syncytial gonad for proper gonad structure and oocyte formation; specifically, ANI-2 appears to be required for maintaining the structure of the rachis, the syncytial compartment of germline cytoplasm that connects developing ooctyes; in the adult gonad, ANI-2 localizes to the surface of the rachis.
42	lips-17	R07G3.2	n/a	chrII 7,609,466	C. elegans LIPS-17 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domains IPR002918 (Lipase, class 2), IPR008262 (Lipase, active site)
43	M151.4	M151.4	n/a	chrII 3,625,534	contains similarity to Interpro domain IPR000533 (Tropomyosin)
44	Y57G11A.5	Y57G11A.5	n/a	chrIV 14,512,160	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
45	T20G5.9	T20G5.9	n/a	chrIII 10,210,308	contains similarity to Pfam domain PF09282 Mago binding contains similarity to Interpro domain IPR015362 (Exon junction complex, Pym)
46	C08F11.1	C08F11.1	n/a	chrIV 13,624,656	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
47	clec-115	C49A1.6	n/a	chrI 14,246,758	C. elegans CLEC-115 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
48	ced-12	Y106G6E.5	n/a	chrI 10,224,961	ced-12 is required both for phagocytotic engulfment of dying (apoptotic) cells, and for normal migrations of healthy cells during development.
49	srb-12	F58A6.10	n/a	chrII 5,153,860	C. elegans SRB-12 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
50	C39E9.11	C39E9.11	n/a	chrIV 13,092,485	C39E9.11 is orthologous to the human gene PAPILLARY RENAL CELL CARCINOMA (TRANSLOCATION-ASSOCIATED) (PRCC; OMIM:179755), which when mutated leads to disease.