UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F13H8.8	F13H8.8	0	chrII 6,266,588	contains similarity to Drosophila hydei Axoneme-associated protein mst101(2).; SW:Q08696
2	F40F9.3	F40F9.3	n/a	chrV 9,715,769	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
3	ZC247.2	ZC247.2	n/a	chrI 10,258,909	contains similarity to Homo sapiens similar to KIAA1203 protein; ENSEMBL:ENSP00000219689
4	aman-3	F48C1.1	n/a	chrI 5,327,364	aman-3 encodes a Co(II)-activated alpha-mannosidase II, orthologous to human MAN2C1; AMAN-3 is predicted to remove mannose residues from the N-linked oligosaccharides of glycoproteins; AMAN-3 contains three predicted N-glycosylation sites; AMAN-3 is biochemically active in vitro, with a pH optimum of 6.5; AMAN-3 requires either Co(II) or Mn(II) for activity, preferring the former ion; since aman-2(tm1078) mutants almost completely lack paucimannosidic glycans, the function of AMAN-3 in vivo is unclear.
5	csp-3	Y47H9C.6	n/a	chrI 11,888,911	csp-3 encodes a protein that is homologous to the C-terminal domain of caspase-like cysteine proteases; unlike other caspases, CSP-3 does not contain a middle or N-terminal domain, and thus may either function in concert with the middle domains of other caspases or may play a regulatory (dominant negative) role in caspase activation; as loss of csp-3 activity via large-scale RNAi does not result in any obvious abnormalities, the precise role of CSP-3 in C. elegans development and/or behavior is not yet known.
6	ech-8	F01G10.2	n/a	chrIV 10,237,849	C. elegans ECH-8 protein; contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR013328 (Dehydrogenase, multihelical), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR016040 (NAD(P)-binding)
7	grd-14	T01B10.2	n/a	chrX 8,500,290	grd-14 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-14 is required for normal growth to full size, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
8	C07H6.3	C07H6.3	n/a	chrIII 7,511,662	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
9	col-89	F17C8.2	n/a	chrIII 4,748,632	C. elegans COL-89 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
10	C18E9.9	C18E9.9	n/a	chrII 8,988,878	contains similarity to Thermoplasma volcanium Hypothetical protein TV1312.; TR:Q978V3
11	T10E9.3	T10E9.3	n/a	chrI 6,536,631	contains similarity to Pfam domain PF03351 DOMON domain contains similarity to Interpro domains IPR005018 (DOMON related), IPR013050 (DOMON)
12	F35C8.2	F35C8.2	n/a	chrX 5,375,578	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	W07B8.3	W07B8.3	n/a	chrV 1,125,705
14	C34C12.4	C34C12.4	n/a	chrIII 3,468,832	contains similarity to Homo sapiens Uncharacterized protein C4orf34; ENSEMBL:ENSP00000295958
15	ttr-12	F46B3.4	n/a	chrV 20,603,550	C. elegans TTR-12 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
16	C32E8.1	C32E8.1	n/a	chrI 3,796,427	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
17	C50C3.2	C50C3.2	n/a	chrIII 8,185,577	contains similarity to Pfam domains PF00435 (Spectrin repeat) (4), PF00036 (EF hand) contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
18	C42C1.6	C42C1.6	n/a	chrIV 12,294,581	contains similarity to Drosophila melanogaster Flybase gene name is CG16970-PA; FLYBASE:CG16970-PA
19	T17H7.7	T17H7.7	n/a	chrIII 756,721
20	srxa-2	F56D5.10	n/a	chrIV 9,423,882	C. elegans SRXA-2 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
21	F42G8.9	F42G8.9	n/a	chrIV 8,117,087
22	srj-39	F38H12.1	n/a	chrV 4,105,406	C. elegans SRJ-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	R10E8.3	R10E8.3	n/a	chrV 18,235,608	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
24	elo-7	F56H11.3	n/a	chrIV 9,530,584	The elo-7 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-7 has no known function in vivo.
25	clec-152	F10F2.6	n/a	chrIII 4,633,383	C. elegans CLEC-152 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	K08D10.9	K08D10.9	n/a	chrIV 4,159,983
27	pqn-54	R09B5.5	n/a	chrV 1,465,672	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
28	C30F12.7	C30F12.7	n/a	chrI 6,975,813	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004434 (Isocitrate dehydrogenase NAD-dependent, mitochondrial), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
29	F42G2.3	F42G2.3	n/a	chrII 2,420,134
30	nhr-266	F56H1.2	n/a	chrI 5,738,931	C. elegans NHR-266 protein; contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR003125 (Protein of unknown function WSN)
31	F41G3.3	F41G3.3	n/a	chrII 6,757,638
32	T05B11.1	T05B11.1	n/a	chrV 7,750,009	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
33	F59F5.7	F59F5.7	n/a	chrX 10,563,070	contains similarity to Interpro domain IPR006609 (Region of unknown function DM13, Skeletor)
34	C25F6.1	C25F6.1	n/a	chrX 5,487,263
35	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
36	plc-2	Y75B12B.6	n/a	chrV 15,195,140	C. elegans PLC-2 protein; contains similarity to Pfam domains PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes)
37	K09C6.2	K09C6.2	n/a	chrV 857,653	contains similarity to Yarrowia lipolytica Similar to sp\|P32583 Saccharomyces cerevisiae YKR092c SRP40 Suppressorsprotein.; TR:Q6CEY9
38	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
39	F36D3.5	F36D3.5	n/a	chrV 16,512,428	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
40	F41C6.7	F41C6.7	n/a	chrX 6,883,839	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
41	Y41C4A.8	Y41C4A.8	n/a	chrIII 11,707,793	contains similarity to Aedes aegypti Hypothetical conserved protein (Putative uncharacterized protein).; TR:Q1HQM0
42	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
43	srz-64	Y57G7A.7	n/a	chrII 1,291,002	C. elegans SRZ-64 protein ;
44	his-57	F54E12.5	n/a	chrIV 11,340,574	his-57 encodes an H2A histone.
45	F59A6.4	F59A6.4	n/a	chrII 5,006,559	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
46	Y70C5C.1	Y70C5C.1	n/a	chrV 16,702,280	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
47	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
48	str-96	T10H4.2	n/a	chrV 15,293,203	C. elegans STR-96 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	C08F11.7	C08F11.7	n/a	chrIV 13,637,874	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR002398 (Peptidase C14, caspase precursor p45)
50	F49D11.6	F49D11.6	n/a	chrI 10,907,943	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)