UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fipr-15	F13E9.3	0.00006	chrIV 10,880,611	C. elegans FIPR-15 protein; contains similarity to Interpro domain IPR005137 (Photosystem I assembly BtpA)
2	Y8A9A.3	Y8A9A.3	n/a	chrII 3,791,812	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
3	ZK632.7	ZK632.7	n/a	chrIII 9,821,105	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
4	B0285.1	B0285.1	n/a	chrIII 4,336,901	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region)
5	B0478.3	B0478.3	n/a	chrIV 6,964,202	contains similarity to Interpro domains IPR013090 (Phospholipase A2, active site), IPR016090 (Phospholipase A2), IPR001211 (Phospholipase A2, eukaryotic)
6	mep-1	M04B2.1	n/a	chrIV 11,526,270	mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain.
7	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
8	lgc-39	F09G2.5	n/a	chrV 7,177,156	C. elegans LGC-39 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
9	C30G12.4	C30G12.4	n/a	chrII 7,262,590	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
10	clh-5	C07H4.2	n/a	chrII 9,096,575	The clh-5 gene encodes a chloride channel, whose human homologs include CLC1 and CLCN5; the latter homolog is imvolved in receptor-mediated endocytosis.
11	F21G4.6	F21G4.6	n/a	chrX 9,913,063	F21G4.6 is orthologous to the human gene HUNTINGTIN (HD; OMIM:143100), which when mutated leads to disease.
12	R03C1.1	R03C1.1	n/a	chrII 14,908,902	contains similarity to Homo sapiens Mucin-5AC precursor (Fragment); ENSEMBL:ENSP00000351148
13	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
14	Y43F8C.8	Y43F8C.8	n/a	chrV 19,644,963	contains similarity to Drosophila melanogaster Flybase gene name is mRpS28-PA;; FLYBASE:CG5497
15	tag-135	D1054.15	n/a	chrV 10,807,021	C. elegans TAG-135 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009146 (Groucho/transducin-like enhancer), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
16	C15B12.1	C15B12.1	n/a	chrX 6,477,878	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
17	ger-1	R01H2.5	n/a	chrIII 7,066,371	C. elegans GER-1 protein; contains similarity to Pfam domain PF01370 NAD dependent epimerase/dehydratase family contains similarity to Interpro domains IPR001509 (NAD-dependent epimerase/dehydratase), IPR002347 (Glucose/ribitol dehydrogenase), IPR016040 (NAD(P)-binding)
18	ver-3	F59F3.1	n/a	chrX 10,995,095	C. elegans VER-3 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) (2), PF00047 (Immunoglobulin domain) (4), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site), IPR013151 (Immunoglobulin)
19	T05F1.9	T05F1.9	n/a	chrI 9,646,642	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILP3
20	ZK1321.1	ZK1321.1	n/a	chrII 9,754,525	contains similarity to Sulfolobus sp NOB8H2 Hypothetical protein.; TR:O93705
21	F09G2.3	F09G2.3	n/a	chrV 7,186,673	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
22	F25B4.5	F25B4.5	n/a	chrV 5,680,736	contains similarity to Interpro domain IPR003107 (RNA-processing protein, HAT helix)
23	spon-1	F10E7.4	n/a	chrII 7,118,495	C. elegans SPON-1 protein; contains similarity to Pfam domains PF06468 (Spondin_N) , PF00090 (Thrombospondin type 1 domain) (5), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) , PF02014 (Reeler domain) contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR003067 (Plasmodium circumsporozoite protein), IPR009465 (Spondin, N-terminal), IPR002861 (Reeler region)
24	F20D1.2	F20D1.2	n/a	chrX 14,972,677	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR000195 (RabGAP/TBC)
25	F11C1.1	F11C1.1	n/a	chrX 12,988,210	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domain IPR010625 (CHCH)
26	sdc-3	C25D7.3	n/a	chrV 15,043,550	sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex.
27	eif-3.G	F22B5.2	n/a	chrII 8,443,436	eif-3.G encodes a homolog of eukaryotic translation initiation factor 3, subunit 4 that affects embryonic viability, fertility, and growth.
28	tag-320	B0403.4	n/a	chrX 7,067,404	C. elegans TAG-320 protein; contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012335 (Thioredoxin fold), IPR005788 (Disulphide isomerase), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related), IPR012336 (Thioredoxin-like fold)
29	dpy-26	C25G4.5	n/a	chrIV 12,448,610	dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.
30	Y37D8A.10	Y37D8A.10	n/a	chrIII 12,875,275	contains similarity to Pfam domain PF06703 Microsomal signal peptidase 25 kDa subunit (SPC25) contains similarity to Interpro domain IPR009582 (Microsomal signal peptidase 25 kDa subunit)
31	T07F12.4	T07F12.4	n/a	chrX 4,897,382	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
32	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
33	lst-2	R160.7	n/a	chrX 4,380,673	C. elegans LST-2 protein; contains similarity to Pfam domain PF01363 FYVE zinc finger contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
34	F37H8.5	F37H8.5	n/a	chrII 11,188,743	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
35	tag-175	D2013.10	n/a	chrII 9,324,253	tag-175 encodes an ortholog of human TMEM41B, whose protein family is ancient (conserved in both animals and plants) but functionally uncharacterized; TAG-175 is broadly expressed (in hypodermis, muscle, neurons, intestine, spermetheca, and vulva); TAG-175 has no known function in vivo, since neither tag-175(RNAi) nor tag-175(gk278) has obvious phenotypes.
36	D2021.8	D2021.8	n/a	chrX 8,552,722	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
37	cul-1	D2045.6	n/a	chrIII 10,473,304	cul-1 encodes a cullin, orthologous to Cdc53/Cul1 in S. cerevisiae and CUL-1 in humans (OMIM:603134), that is required both maternally and zygotically for developmentally programmed transitions from the G1 phase of the cell cycle to the GO phase or the apoptotic pathway, and that is probably also required for normally slow G1-to-S phase progression; CUL-1 physically interacts with eight Skp1-related proteins (SKR-1, -2, -3, -4, -7, -8, -9, and -10).
38	BE10.2	BE10.2	n/a	chrIII 12,795,671	contains similarity to Homo sapiens Transmembrane protein 195; ENSEMBL:ENSP00000341662
39	F18H3.4	F18H3.4	n/a	chrX 13,530,481	contains similarity to Mus musculus GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).; SW:Q8VD04
40	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
41	T07F8.2	T07F8.2	n/a	chrII 7,145,876	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
42	C25A1.4	C25A1.4	n/a	chrI 10,171,209	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
43	F35C11.4	F35C11.4	n/a	chrII 8,250,751	contains similarity to Homo sapiens Uncharacterized protein C9orf125; ENSEMBL:ENSP00000363980
44	kin-3	B0205.7	n/a	chrI 10,735,304	kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
45	W08F4.7	W08F4.7	n/a	chrII 576,333
46	goa-1	C26C6.2	n/a	chrI 7,524,411	goa-1 encodes an ortholog of the heterotrimeric G protein alpha subunit Go (Go/Gi class) that affects normal locomotion, egg-laying, and male mating; it genetically interacts with the egl-30 pathway, and is expressed in all neurons and sex-specific muscles.
47	F42H10.3	F42H10.3	n/a	chrIII 8,486,094	contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF00018 (SH3 domain) , PF00880 (Nebulin repeat) (2), PF00412 (LIM domain) contains similarity to Interpro domains IPR000900 (Nebulin 35 residue motif), IPR013998 (Nebulin), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR011511 (Variant SH3), IPR001781 (Zinc finger, LIM-type)
48	fce-1	C04F12.10	n/a	chrI 9,711,884	fce-1 encodes an ortholog of 'farnesylated-proteins converting enzyme 1' (FACE-1), and thus probably enables post-translational processing of proteins (such as LET-60/RAS) carrying a C-terminal CaaX motif; FCE-1 protein probably accounts for the EDTA-sensitive, tosylphenylalanylchloromethane-insensitive component of CaaX-proteolytic activity in membrane extracts from C. elegans, and FCE-1 can cleave a farnesylated peptide in vitro; the S. cerevisiae homolog of FCE-1 (Ste24p) cleaves the precursor of yeast a-factor mating pheromone after its farnesylated cysteine residue, and transgenic FCE-1 rescues a mating defect of mutant yeast lacking both the Ste24p and the Rce1p CaaX-proteases.
49	F33H2.5	F33H2.5	n/a	chrI 15,009,733	contains similarity to Pfam domains PF00136 (DNA polymerase family B) , PF03104 (DNA polymerase family B, exonuclease domain) , PF08490 (Domain of unknown function (DUF1744)) contains similarity to Interpro domains IPR006055 (Exonuclease), IPR006172 (DNA-directed DNA polymerase, family B), IPR006133 (DNA-directed DNA polymerase, family B, exonuclease), IPR006134 (DNA-directed DNA polymerase, family B, conserved region), IPR013697 (Region of unknown function DUF1744), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
50	unc-116	R05D3.7	n/a	chrIII 8,353,130	unc-116 encodes a kinesin-1 heavy chain orthologue; UNC-116 is predicted to function as an an anterograde microtubule-based motor and its activity is required for normal early translocation of the meiotic spindle to the oocyte cortex, cortical positioning of the meiosis II spindle, polar body formation, locomotion, and larval development; in regulating meiotic spindle translocation, UNC-116 may function as part of a complex containing the kinesin light chain KLC-2 and a novel cargo adaptor protein, KCA-1.