UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F13B12.3	F13B12.3	0	chrIV 10,441,433	contains similarity to Tetraodon nigroviridis Chromosome 12 SCAF8721, whole genome shotgun sequence. (Fragment).; TR:Q4T6K3
2	C03A3.3	C03A3.3	n/a	chrX 11,268,134	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
3	C32B5.5	C32B5.5	n/a	chrII 974,906	contains similarity to Pfam domain PF00646 F-box domain
4	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
5	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
7	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
8	T02B11.6	T02B11.6	n/a	chrV 887,079	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
9	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
10	trxr-2	ZK637.10	n/a	chrIII 8,915,015	C. elegans TRXR-2 protein; contains similarity to Pfam domains PF02852 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR012999 (Pyridine nucleotide-disulphide oxidoreductase, class I, active site), IPR004099 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation), IPR006338 (Thioredoxin and glutathione reductase selenoprotein), IPR016156 (FAD/NAD-linked reductase, dimerisation), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR000815 (Mercuric reductase), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
11	his-45	B0035.10	n/a	chrIV 11,326,794	his-45 encodes an H3 histone.
12	F22F1.3	F22F1.3	n/a	chrX 8,162,399	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
13	tbx-31	C36C9.2	n/a	chrX 1,672,652	tbx-31 encodes a diverged member of the T-box transcription factor family; by homology, TBX-31 is predicted to function as a transcriptional regulator during development, but as loss of tbx-31 activity via RNAi results in no obvious defects, the precise role of TBX-31 in C. elegans development and/or behavior is not yet known.
14	Y75B8A.14	Y75B8A.14	n/a	chrIII 12,217,589	contains similarity to Pfam domain PF03029 Conserved hypothetical ATP binding protein contains similarity to Interpro domain IPR004130 (Protein of unknown function, ATP binding)
15	srm-1	T28H11.2	n/a	chrIV 5,013,566	C. elegans SRM-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
16	fut-2	EGAP9.2	n/a	chrV 6,574,873	fut-2 encodes a unique alpha 1,2-fucosyltransferase specifically expressed in intestinal cells of larval and adult animals; recombinant FUT-2 expressed in human 293T cells exhibits a novel acceptor specificity profile compared with mammalian alpha 1,2-fucosyltransferases and the predicted protein shares very low amino acid identity with human alpha 1,2-fucosyltransferases, but its predicted type 2 topology and domain structure are typical of other glucosyltransferases.
17	srg-5	T12A2.11	n/a	chrIII 6,263,078	C. elegans SRG-5 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
18	ZK892.6	ZK892.6	n/a	chrII 9,979,541	contains similarity to Vibrio parahaemolyticus Hypothetical protein.; TR:Q87PB2
19	sma-3	R13F6.9	n/a	chrIII 6,862,404	sma-3 encodes a Smad protein; during development, SMA-3 functions as part of a DBL-1/SMA-6 TGF-beta-related signaling pathway that controls body size and male tail sensory ray and spicule formation; sma-3 is widely expressed at all developmental stages, beginning during embryogenesis, continuing through all larval stages, and seen very strongly in adult hermaphrodites and males; a SMA-3::GFP is detected in the pharynx, intestine, and hypodermis and localizes to the nucleus; sma-3 expression in the hypodermis is necessary and sufficient for normal body size; SMA-3 can physically interact with the LIN-31 forkhead transcription factor.
20	F58B6.1	F58B6.1	n/a	chrIII 1,114,111	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
21	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
23	srw-136	K12D9.10	n/a	chrV 3,009,736	C. elegans SRW-136 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
24	B0041.3	B0041.3	n/a	chrI 4,645,153	contains similarity to Pfam domain PF01476 LysM domain contains similarity to Interpro domain IPR002482 (Peptidoglycan-binding LysM)
25	sra-8	AH6.12	n/a	chrII 9,538,328	C. elegans SRA-8 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
26	R10E11.5	R10E11.5	n/a	chrIII 9,787,703	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
27	tat-6	F02C9.3	n/a	chrV 3,131,186	C. elegans TAT-6 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
28	ZK938.3	ZK938.3	n/a	chrII 9,832,928	contains similarity to Pfam domain PF00612 IQ calmodulin-binding motif contains similarity to Interpro domain IPR000048 (IQ calmodulin-binding region)
29	F38B6.6	F38B6.6	n/a	chrX 6,687,229	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (4), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (5)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
30	srsx-1	F40D4.5	n/a	chrV 17,177,360	C. elegans SRSX-1 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
31	B0554.5	B0554.5	n/a	chrV 425,501	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)
32	ceh-23	ZK652.5	n/a	chrIII 7,840,469	The ceh-23 gene encodes a homeodomain protein required for a specific differentiated trait of the thermosensory interneuron AIY.
33	T18D3.7	T18D3.7	n/a	chrX 12,442,974	contains similarity to Pfam domain PF01166 TSC-22/dip/bun family contains similarity to Interpro domain IPR000580 (TSC-22 / Dip / Bun)
34	srg-33	F21F8.1	n/a	chrV 8,292,769	C. elegans SRG-33 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
35	C31B8.12	C31B8.12	n/a	chrV 2,926,103	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
36	C33D12.2	C33D12.2	n/a	chrX 3,043,877	C33D12.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C33D12.2 may participate in metal homoeostasis; C33D12.2 is expressed in intestine, body wall muscle, nervous system (including ventral and dorsal nerve cords and head neurons), and adult vulval muscle and reproductive system; C33D12.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C33D12.2 has no obvious function in RNAi assays.
37	F59D12.1	F59D12.1	n/a	chrX 15,669,484	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
40	str-16	Y73C8A.1	n/a	chrV 3,239,764	C. elegans STR-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
41	gpa-13	F18E2.5	n/a	chrV 12,753,806	gpa-13 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASH, AWC, PHA, and PHB.
42	nlp-13	E03D2.1	n/a	chrV 4,237,211	nlp-13 encodes a predicted neuropeptide of the MSFamide family; expressed primarily in neurons or in the endocrine/secretory cells, and expression includes pharyngeal neurons that modulate pharyngeal pumping of food.
43	K02D3.2	K02D3.2	n/a	chrX 13,710,264	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
44	F59A3.1	F59A3.1	n/a	chrI 5,525,077	F59A3.1 encodes one of two C. elegans carboxypeptidase D homologs; loss of F59A3.1 activity via large-scale RNAi screens in a sensitized, rrf-3 mutant background results in larval lethality, abnormal locomotion, and abnormal morphogenesis of the vulval epithelium resulting in rupture; high-throughput expression studies report F59A3.1 expression in the pharynx only.
45	str-46	C31B8.6	n/a	chrV 2,899,200	C. elegans STR-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srbc-81	Y45G12C.8	n/a	chrV 2,523,361	C. elegans SRBC-81 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002229 (Blood group Rhesus C/E and D polypeptide)
47	C25A1.5	C25A1.5	n/a	chrI 10,178,041	contains similarity to Pfam domains PF04116 (Fatty acid hydroxylase superfamily) , PF00173 (Cytochrome b5-like Heme/Steroid binding domain) contains similarity to Interpro domains IPR006694 (Fatty acid hydroxylase), IPR001199 (Cytochrome b5)
48	C50F7.6	C50F7.6	n/a	chrIV 7,721,871	contains similarity to Homo sapiens Isoform 4 of PDZ domain-containing RING finger protein 4; ENSEMBL:ENSP00000370169
49	C39D10.1	C39D10.1	n/a	chrX 7,906,986
50	ZC53.4	ZC53.4	n/a	chrX 1,931,714	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227Y0