UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F12A10.6	F12A10.6	2e-70	chrII 5,494,268
2	gur-4	K09E4.5	n/a	chrII 14,106,298	C. elegans GUR-4 protein ;
3	E03A3.5	E03A3.5	n/a	chrIII 4,061,679	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold)
4	ZC15.3	ZC15.3	n/a	chrV 20,299,636	contains similarity to Homo sapiens Myosin heavy chain, smooth muscle isoform; ENSEMBL:ENSP00000300036
5	ocr-2	T09A12.3	n/a	chrIV 8,216,912	ocr-2 encodes a TRPV (transient receptor potential channel, vanilloid subfamily) ion channel; OCR-2 activity is required for several types of sensory transduction including olfaction, osmosensation, mechanosensation, and chemosensation; an OCR-2 fusion protein is expressed in sensory cilia and requires the OSM-9 TRPV channel protein for proper localization; likewise, OSM-9 requires OCR-2 for its cilial localization.
6	src-2	F49B2.5	n/a	chrI 14,325,568	C. elegans SRC-2 protein; contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00018 (SH3 domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR000719 (Protein kinase, core), IPR013315 (Spectrin alpha chain), IPR011511 (Variant SH3), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
7	ham-1	F53B2.6	n/a	chrIV 12,543,852	ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
8	F45E1.2	F45E1.2	n/a	chrX 8,003,850
9	Y39A3B.3	Y39A3B.3	n/a	chrIII 1,986,275
10	srh-174	F40D4.1	n/a	chrV 17,179,348	C. elegans SRH-174 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	ZK938.6	ZK938.6	n/a	chrII 9,844,266	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
12	rac-2	K03D3.10	n/a	chrIV 16,308,987	rac-2 encodes a small Rho family GTPase that, along with CED-10 and MIG-2, is one of three C. elegans Rac-related proteins; genetic studies indicate that rac-2 functions redundantly with mig-2 and ced-10 to regulate CAN and PDE axon pathfinding and CAN cell migration; in addition, rac-2 functions slightly redundant with mig-2 during distal tip cell movement and slightly redundant with ced-10 during cell-corpse phagocytosis; as unc-73 mutations enhance rac-2 defects in axon pathfinding and CAN cell migration, UNC-73/Trio is a likely candidate to act upstream of RAC-2 and positively regulate its GTPase activity in vivo; further, as UNC-115 activity is required to mediate the morphogenetic effects of constitutively active RAC-2(G12V), UNC-115, an actin-binding protein, is likely to be a downstream effector of RAC-2; GFP::RAC-2 reporters expressed in neurons and neuroblasts reveal localization at cell margins and the nerve ring, the latter suggesting that GFP::RAC-2 associates with the axonal plasma membrane.
13	srab-10	C36C5.7	n/a	chrV 3,143,828	C. elegans SRAB-10 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
14	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
15	F31F7.2	F31F7.2	n/a	chrV 6,272,906	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
16	F54C4.3	F54C4.3	n/a	chrIII 78,455	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
17	sra-1	AH6.4	n/a	chrII 9,520,857	sra-1 encodes a predicted seven transmembrane receptor; expressed in the male SPD and SPV neurons.
18	F25H2.2	F25H2.2	n/a	chrI 10,544,713	contains similarity to Pfam domains PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00787 (PX domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR001683 (Phox-like), IPR001478 (PDZ/DHR/GLGF)
19	srj-5	F31F4.16	n/a	chrV 652,439	C. elegans SRJ-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	Y54E2A.10	Y54E2A.10	n/a	chrII 14,791,729	contains similarity to Dictyostelium discoideum Protein-tyrosine phosphatase 3 (EC 3.1.3.48) (Protein-tyrosine-sphosphate phosphohydrolase 3).; SW:PTP3_DICDI
21	tag-120	F40F9.2	n/a	chrV 9,708,653	tag-120 encodes a predicted transmembrane protein; as loss of tag-120 activity via RNAi does not result in any abnormalities, the precise role of TAG-120 in C. elegans development and/or behavior is not yet known; however, TAG-120 is homologous to a Drosophila NMDA receptor-associated protein and mammalian transmembrane proteins that function in Fas-mediated cell death, so TAG-120 may play a role in neuronal functions and/or apoptosis; a tag-120 reporter fusion is expressed in the nervous system, pharyngeal muscles, and to a lesser extent in the excretory system.
22	T07H6.4	T07H6.4	n/a	chrX 6,284,028	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR002396 (Selectin (CD62E/L/P antigen)), IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
23	tag-117	C01B7.4	n/a	chrV 8,794,107	C. elegans TAG-117 protein; contains similarity to Pfam domains PF00018 (SH3 domain) , PF00625 (Guanylate kinase) , PF07653 (Variant SH3 domain) , PF00595 (PDZ domain (Also known as DHR or GLGF)) contains similarity to Interpro domains IPR011511 (Variant SH3), IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001478 (PDZ/DHR/GLGF), IPR001452 (Src homology-3)
24	Y6B3B.1	Y6B3B.1	n/a	chrI 13,699,504	contains similarity to Interpro domain IPR000533 (Tropomyosin)
25	lact-3	M28.6	n/a	chrII 10,654,998	lact-3 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence; loss of lact-3 activity via RNAi has been reported to result in reduced fat content.
26	abf-4	Y38H6C.22	n/a	chrV 20,553,545	abf-4 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-4 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
27	shw-3	R186.5	n/a	chrV 12,974,845	C. elegans SHW-3 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003973 (Potassium channel, voltage dependent, Kv2), IPR003970 (Potassium channel, voltage dependent, Kv8), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003969 (Potassium channel, voltage dependent, Kv6), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
28	C24A8.1	C24A8.1	n/a	chrX 4,323,582	C24A8.1 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3; C24A8.1 is expressed in the nervous system; because of its paralogy, C24A8.1 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants; but C24A8.1 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
29	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
30	srw-36	F14F8.7	n/a	chrV 16,684,004	C. elegans SRW-36 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
31	B0554.3	B0554.3	n/a	chrV 434,275
32	C07G3.8	C07G3.8	n/a	chrV 3,497,698	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
33	glr-3	K10D3.1	n/a	chrI 7,119,675	glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron.
34	clec-22	F49A5.3	n/a	chrV 16,859,205	C. elegans CLEC-22 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
35	clec-113	F47G4.1	n/a	chrI 14,055,730	C. elegans CLEC-113 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
36	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
37	R03G8.1	R03G8.1	n/a	chrX 13,086,031	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
38	AC8.7	AC8.7	n/a	chrX 230,898
39	F15A8.1	F15A8.1	n/a	chrX 4,441,526
40	str-15	T08G3.1	n/a	chrV 16,458,013	C. elegans STR-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F38C2.4	F38C2.4	n/a	chrIV 16,270,980	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
42	nas-39	F38E9.2	n/a	chrX 16,464,603	C. elegans NAS-39 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (2), PF00431 (CUB domain) (4), PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR015446 (Bone morphogenetic protein 1/tolloid-like protein), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR001506 (Peptidase M12A, astacin), IPR006210 (EGF), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding)
43	F21E9.6	F21E9.6	n/a	chrX 1,356,015
44	ZC416.1	ZC416.1	n/a	chrIV 3,637,332	n/a
45	T15B7.10	T15B7.10	n/a	chrV 6,811,130	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
46	F58H1.4	F58H1.4	n/a	chrV 11,937,362	contains similarity to Interpro domain IPR006207 (Cystine knot, C-terminal)
47	F59A3.10	F59A3.10	n/a	chrI 5,542,985
48	K02E10.5	K02E10.5	n/a	chrX 2,477,930
49	sru-25	F31F4.14	n/a	chrV 673,072	C. elegans SRU-25 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
50	F23F1.3	F23F1.3	n/a	chrII 32,686