UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F11E6.6	F11E6.6	4e-137	chrIV 17,465,196	contains similarity to Homo sapiens Damage-regulated autophagy modulator; ENSEMBL:ENSP00000258534
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	nhr-254	ZK6.5	n/a	chrV 393,883	C. elegans NHR-254 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	T05H4.4	T05H4.4	n/a	chrV 6,439,469	The T05H4.4 gene encodes a homolog of the human gene B5R, which when mutated leads to methemoglobinemia (OMIM:250800).
5	Y39A1A.17	Y39A1A.17	n/a	chrIII 10,688,996	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
6	Y49G5B.1	Y49G5B.1	n/a	chrV 5,228,330	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
7	lgc-40	T24D8.1	n/a	chrX 2,362,451	C. elegans LGC-40 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
8	pgp-10	C54D1.1	n/a	chrX 7,162,476	pgp-10 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-10 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-10 activity via RNAi results in no obvious defects, the exact role of pgp-10 in C. elegans development and/or behavior is not yet known; pgp-10 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and hypodermis.
9	Y75B8A.11	Y75B8A.11	n/a	chrIII 12,188,150	contains similarity to Lymnaea stagnalis Neuropeptide Y precursor.; TR:Q9U0S9
10	scc-1	F10G7.4	n/a	chrII 4,699,843	scc-1 encodes a member of the Rad21/Rec8-like family of cohesion proteins that affects embryonic viability, fertility, the rate of embryonic cell divisions and the incidence of male progeny; interacts with ATL-1, F56D12.5, and F11E6.1 based on yeast two-hybrid assays, and is expressed in nondividing embryonic and germline nuclei.
11	pqn-25	D1044.3	n/a	chrIII 5,510,853	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
12	F47G9.4	F47G9.4	n/a	chrV 11,319,469	contains similarity to Pfam domain PF00643 B-box zinc finger contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
13	K03B8.8	K03B8.8	n/a	chrV 11,410,221	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
14	egl-36	R07A4.1	n/a	chrX 10,739,267	egl-36 encodes a Shaw-type voltage-gated potassium channel that regulates egg laying and defecation; expression of egl-36::gfp reporters is observed in several different cell types including muscle cells such as the uterine and vulval egg-laying muscles, sensory, motor and interneurons, and the distal tip cells of the gonad; when expressed in a heterologous system, EGL-36 exhibits channel activity.
15	cyp-43A1	E03E2.1	n/a	chrX 5,716,005	C. elegans CYP-43A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
16	hsp-16.48	T27E4.3	n/a	chrV 9,088,350	hsp-16.48 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; an hsp-16.48 reporter fusion, expressed broadly but most strongly in body muscle and hypodermis, is induced solely in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.48 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating.
17	his-68	T23D8.6	n/a	chrI 9,989,347	his-68 encodes an H2A histone.
18	F48G7.12	F48G7.12	n/a	chrV 644,981	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
19	ZC317.2	ZC317.2	n/a	chrV 5,460,748
20	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
21	frm-7	C51F7.1	n/a	chrV 12,304,705	C. elegans FRM-7 protein; contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR000299 (Band 4.1, N-terminal)
22	F36A2.2	F36A2.2	n/a	chrI 8,803,215	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
23	fip-4	F41E6.10	n/a	chrV 8,611,069	C. elegans FIP-4 protein
24	C29E6.4	C29E6.4	n/a	chrIV 11,881,077	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
25	rrf-2	M01G12.12	n/a	chrI 12,102,320	rrf-2 encodes an RNA-directed RNA polymerase (RdRP) homolog of unknown function; RRF-2 is not obviously required for either somatic or germline RNAi, or for transitive RNAi.
26	R11.3	R11.3	n/a	chrX 16,198,339	contains similarity to Haemophilus influenzae Hypothetical protein HI0386.; SW:YBGC_HAEIN
27	K01A12.3	K01A12.3	n/a	chrX 8,622,819	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
28	F49C12.4	F49C12.4	n/a	chrIV 9,303,356	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
29	R53.4	R53.4	n/a	chrII 9,967,683	contains similarity to Homo sapiens 10 kDa protein; ENSEMBL:ENSP00000377740
30	Y43F8B.13	Y43F8B.13	n/a	chrV 19,459,852	contains similarity to Puumala virus Nucleocapsid protein (Fragment).; TR:Q8B3A4
31	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
32	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
33	tag-77	C28C12.10	n/a	chrIV 8,506,971	C. elegans TAG-77 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR000306 (Zinc finger, FYVE-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011993 (Pleckstrin homology-type), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
34	E04D5.4	E04D5.4	n/a	chrII 10,441,286	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
35	sid-2	ZK520.2	n/a	chrIII 13,680,827	sid-2 encodes a novel, single-pass transmembrane protein; SID-2 is required for environmental-mediated (i.e. ingestion or soaking) RNA interference (RNAi); SID-2::GFP is expressed strongly in the intestine where it localizes to the apical (lumenal) membrane; SID-2::GFP is also expressed at much lower levels in the excretory duct cells; when expressed in Caenorhabditis briggsae, a related nematode species deficient for environmental RNAi, SID-2 is able to confer environmental RNAi.
36	B0222.1	B0222.1	n/a	chrV 9,134,798	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domains IPR003566 (T-cell surface glycoprotein CD5), IPR002619 (Protein of unknown function CX), IPR000694 (Proline-rich region)
37	srh-245	F31F4.9	n/a	chrV 655,327	C. elegans SRH-245 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	srd-43	R04D3.9	n/a	chrX 13,304,796	C. elegans SRD-43 protein ;
39	F39F10.2	F39F10.2	n/a	chrX 16,895,317	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
40	nit-1	ZK1058.6	n/a	chrIII 3,923,096	C. elegans NIT-1 protein; contains similarity to Pfam domain PF00795 Carbon-nitrogen hydrolase contains similarity to Interpro domains IPR003010 (Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase), IPR000132 (Nitrilase/cyanide hydratase, conserved site)
41	K08B5.2	K08B5.2	n/a	chrX 16,552,470
42	C50F2.1	C50F2.1	n/a	chrI 3,893,803	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
43	C01B10.9	C01B10.9	n/a	chrIV 6,633,581	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR017850 (Alkaline-phosphatase-like, core domain)
44	lin-31	K10G6.1	n/a	chrII 3,984,762	lin-31 encodes a winged helix (WH)-like transcription factor that is a member of the HNF3/Forkhead family of DNA-binding proteins; LIN-31 acts as a tissue-specific effector of MAP kinase-mediated signaling in the vulva; when MAP kinase is inactive, LIN-31 forms a complex with LIN-1/Ets that inhibits vulval cell fates; upon MAP kinase activation (vulval induction), LIN-31 becomes phosphorylated, dissociates from LIN-1, and goes on to promote primary and secondary vulval cell fates; LIN-31 is expressed in the vulval precursor cells.
45	C04C3.6	C04C3.6	n/a	chrIV 3,421,207	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	F14F8.8	F14F8.8	n/a	chrV 16,671,873	contains similarity to Saccharomyces cerevisiae Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP; SGD:YHR143W
47	K05G3.2	K05G3.2	n/a	chrX 16,497,319
48	B0412.3	B0412.3	n/a	chrIII 802,243	contains similarity to Pfam domain PF07919 Protein of unknown function (DUF1683) contains similarity to Interpro domain IPR012880 (Protein of unknown function DUF1683, C-terminal)
49	abf-4	Y38H6C.22	n/a	chrV 20,553,545	abf-4 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-4 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
50	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.