UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	unc-122	F11C3.2	0	chrI 14,873,757	unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F29F11.3	F29F11.3	n/a	chrV 10,658,900	contains similarity to Drosophila melanogaster Flybase gene name is CG10189-PA;; FLYBASE:CG10189
4	sor-3	C04E7.2	n/a	chrX 355,777	sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus.
5	osm-10	T20H4.1	n/a	chrIII 7,244,451	osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons.
6	C05G5.3	C05G5.3	n/a	chrX 14,751,355	contains similarity to Homo sapiens Isoform 1 of Matrix-remodeling-associated protein 7; ENSEMBL:ENSP00000348050
7	R07B1.9	R07B1.9	n/a	chrX 9,879,387	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g15170).; TR:Q8L731
8	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
9	K08C9.5	K08C9.5	n/a	chrI 11,483,971	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
10	Y45F10B.12	Y45F10B.12	n/a	chrIV 13,587,824	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
11	K10H10.6	K10H10.6	n/a	chrII 14,504,011	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
12	F56D5.5	F56D5.5	n/a	chrIV 9,407,671	contains similarity to Interpro domain IPR000533 (Tropomyosin)
13	mec-6	W02D3.3	n/a	chrI 6,726,624	mec-6 is homologous to the human PARAOXONASE 1 gene (PON1, OMIM:168820), which in some allelic forms is associated with susceptibility to coronary artery disease; MEC-6 protein interacts physically with the MEC-4 degenerin ion channel, is colocalized with it in vivo, and is required for MEC-4 punctate expression along touch-receptor neural processes.
14	F42G8.5	F42G8.5	n/a	chrIV 8,137,753
15	F46F11.7	F46F11.7	n/a	chrI 5,621,853	contains similarity to Interpro domain IPR011061 (Proteinase inhibitor I14/I15, hirudin/antistatin)
16	W01C9.1	W01C9.1	n/a	chrII 8,533,713	contains similarity to Brugia pahangi Heat shock protein 90.; SW:HS90_BRUPA
17	fbxa-52	F07G6.6	n/a	chrX 1,710,748	C. elegans FBXA-52 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
18	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
19	lact-7	C40H5.4	n/a	chrX 11,762,779	lact-7 encodes a beta-lactamase domain-containing protein.
20	F41C3.6	F41C3.6	n/a	chrII 4,735,969
21	F57B7.2	F57B7.2	n/a	chrV 11,442,786	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
22	F40G12.6	F40G12.6	n/a	chrV 14,272,120	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
23	C41D11.6	C41D11.6	n/a	chrI 4,461,426
24	lin-32	T14F9.5	n/a	chrX 2,229,639	lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons.
25	B0250.2	B0250.2	n/a	chrV 20,473,310	contains similarity to Drosophila erecta Female-specific transformer protein.; SW:TRSF_DROER
26	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
27	B0250.8	B0250.8	n/a	chrV 20,465,482	contains similarity to Mycoplasma mycoides FtsY protein.; TR:O05289
28	fbxa-10	T12B5.3	n/a	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	cdh-4	F25F2.2	n/a	chrIII 4,528,691	A homolog of a member of the cadherin superfamily that is involved in cell-cell adhesion.
30	cdh-8	F18F11.3	n/a	chrIV 351,612	cdh-8 encodes a cadherin that may be nematode specific; CDH-8 is predicted to function as a membrane protein that plays a role in cell adhesion and/or morphogenesis, but as loss of cdh-8 activity via mutation or large-scale RNAi experiments results in no obvious abnormalities, the precise role of cdh-8 in C. elegans development and/or behavior is not yet known.
31	M01F1.7	M01F1.7	n/a	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
32	unc-130	C47G2.2	n/a	chrII 11,282,880	A member of the forkhead domain family of transcription factors that affects the generation of the AWA and ASG chemosensory neurons and is partially required for male tail morphogenesis and embryogenesis; it is expressed in the AWA and ASG precursors; it is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor.
33	Y56A3A.11	Y56A3A.11	n/a	chrIII 11,896,407	contains similarity to Pfam domain PF01974 tRNA intron endonuclease, catalytic C-terminal domain contains similarity to Interpro domains IPR006677 (tRNA intron endonuclease, catalytic domain-like), IPR011856 (Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)
34	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
35	T07F12.3	T07F12.3	n/a	chrX 4,887,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
36	igcm-2	SSSD1.1	n/a	chrX 6,382,121	igcm-2 encodes a protein containing immunoglobulin and fibronectin repeats; igcm-2 promoter::gfp fusions are expressed in the PVT interneuron, in some head neurons, and in the pharynx and intestine.
37	F25G6.1	F25G6.1	n/a	chrV 8,577,457
38	T20F7.6	T20F7.6	n/a	chrX 16,867,473	contains similarity to Pfam domain PF00571 CBS domain pair contains similarity to Interpro domain IPR000644 (Cystathionine beta-synthase, core)
39	F21D5.9	F21D5.9	n/a	chrIV 8,724,343	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
40	B0212.1	B0212.1	n/a	chrIV 3,575,057	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
41	T22C8.3	T22C8.3	n/a	chrII 8,621,191	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
42	srx-47	E02C12.3	n/a	chrV 9,350,632	C. elegans SRX-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
43	srh-47	T03F7.4	n/a	chrV 11,299,983	C. elegans SRH-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006069 (ATPase, P-type cation exchange, alpha subunit)
44	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
45	hpl-1	K08H2.6	n/a	chrX 13,246,140	hpl-1 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; loss of hpl-1 activity alone results in no obvious defects, but animals doubly mutant for hpl-1 and hpl-2 have defects in larval, somatic gonad and germline development; in addition, hpl-1 functions redundantly with hpl-2 and lin-13 in vulval development; rescuing HPL-1::GFP fusion proteins are expressed in nuclei throughout the life cycle, beginning at approximately the 50-cell stage of embryogenesis and continuing through larval and adult stages; expression is observed in most, but not all, cells and is particularly strong in head and tail hypodermal and neuronal nuclei; in nuclei, HPL-1::GFP is seen in foci that do not significantly overlap with those of HPL-2.
46	ncs-1	C44C1.3	n/a	chrX 961,929	The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients.
47	W01C9.2	W01C9.2	n/a	chrII 8,537,366	contains similarity to Chlamydia pneumoniae Probable serine/threonine-protein kinase 1 (EC 2.7.1.37).; SW:PKN1_CHLPN
48	F15A4.5	F15A4.5	n/a	chrII 12,470,242	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ICX2
49	R05G6.5	R05G6.5	n/a	chrIV 7,509,013	contains similarity to Pfam domain PF05186 Dpy-30 motif contains similarity to Interpro domains IPR001564 (Nucleoside diphosphate kinase, core), IPR007858 (Dpy-30)
50	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)