UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F10E9.7	F10E9.7	5.000000000000001e-75	chrIII 8,306,002	contains similarity to Interpro domain IPR016193 (Cytidine deaminase-like)
2	cic-1	H14E04.5	n/a	chrIII 2,397,836	C. elegans CIC-1 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
3	C14A4.11	C14A4.11	n/a	chrII 10,606,420	contains similarity to Pfam domain PF06840 Protein of unknown function (DUF1241) contains similarity to Interpro domain IPR009652 (Protein of unknown function DUF1241)
4	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
5	C17H11.5	C17H11.5	n/a	chrX 8,183,262
6	ceh-5	C16C2.1	n/a	chrI 9,727,604	ceh-5 encodes a homeodomain protein, similar to the human VENTRAL ANTERIOR HOMEO BOX 2 gene (VAX2; OMIM:604295); CEH-5 is dispensable for viability and gross morphology.
7	T12E12.3	T12E12.3	n/a	chrIV 5,543,170
8	R05F9.9	R05F9.9	n/a	chrII 4,900,966
9	K09A11.1	K09A11.1	n/a	chrX 13,263,425	contains similarity to Pfam domains PF05699 (hAT family dimerisation domain) , PF02892 (BED zinc finger) contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
10	rfc-2	F58F6.4	n/a	chrIV 1,350,136	rfc-2 encodes a member of the AAA family that are ATPases associated with DNA replication and has highest similarity to the mouse Replication factor C 40 kDa subunit, and affects embryonic viability, fertility, and locomotion in a large-scale RNAi screen.
11	atg-16.1	F02E8.5	n/a	chrX 4,461,104	atg-16.1 encodes a divergent ortholog of the autophagic budding yeast protein Atg16p, and of human ATG16L1 (OMIM:610767, associated with Crohn disease) and ATG16L2; ATG-16.1 is paralogous to ATG-16.2; ATG-16.1 is expressed in larval and adult intestine, renal gland cells, stomato-intestinal muscle, anal depressor muscle, and head mesodermal cell; ATG-16.1 has no obvious function in mass RNAi assays.
12	spat-1	F57C2.6	n/a	chrII 14,531,337	spat-1 encodes a divergent ortholog of Drosophila melanogaster AURORA BOREALIS (BORA) and human BORA (OMIM:610510); SPAT-1 is specifically required for PAR protein-dependent cell-polarity; RNAi of spat-1 weakly suppresses the embryonic lethality of par-2(it5ts) at restrictive temperature.
13	F47E1.1	F47E1.1	n/a	chrX 9,075,645
14	his-63	F22B3.2	n/a	chrIV 11,406,611	his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus.
15	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
16	C14F11.2	C14F11.2	n/a	chrX 6,211,298	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (6), PF00307 (Calponin homology (CH) domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR003590 (Leucine-rich repeat, ribonuclease inhibitor subtype)
17	T02G6.6	T02G6.6	n/a	chrI 11,821,054	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
18	F01G12.1	F01G12.1	n/a	chrX 16,395,930	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
19	lips-3	F10F2.3	n/a	chrIII 4,617,677	C. elegans LIPS-3 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
20	F12A10.1	F12A10.1	n/a	chrII 5,497,839	contains similarity to Oryza sativa subsp indica Putative uncharacterized protein.; TR:A2YC95
21	gad-1	T05H4.14	n/a	chrV 6,432,396	The gad-1 gene encodes a WD repeat-containing protein that is required maternally for gastrulation initiation during early embryogenesis by regulating the division timing, spindle orientation, and subsequent inward migration of the two gut precusor (E) cells at the 26-cell stage.
22	C36B7.4	C36B7.4	n/a	chrX 7,086,834
23	srh-17	C47E8.2	n/a	chrV 14,662,094	C. elegans SRH-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
25	srgp-1	F12F6.5	n/a	chrIV 11,574,575	C. elegans SRGP-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00611 (Fes/CIP4 homology domain) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000198 (RhoGAP)
26	str-134	C05E4.6	n/a	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	B0212.3	B0212.3	n/a	chrIV 3,541,891	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR001202 (WW/Rsp5/WWP)
28	T08A9.6	T08A9.6	n/a	chrX 7,312,318	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
29	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
30	tag-313	Y66H1A.3	n/a	chrIV 444,376	C. elegans TAG-313 protein ; contains similarity to Bos taurus 39S ribosomal protein L55, mitochondrial precursor (L55mt) (MRP-L55).; SW:P0C2B8
31	W09C5.9	W09C5.9	n/a	chrI 13,661,170	contains similarity to Lactococcus lactis Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartatestranscarbamylase) (ATCase).; SW:PYRB_LACLA
32	fbxb-78	E04A4.1	n/a	chrIV 4,738,137	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
33	spr-5	Y40B1B.6	n/a	chrI 13,443,987	spr-5 encodes the C. elegans ortholog of the human histone demethylase LSD1 (lysine-specific demethylase 1) that functions to mediate chromatin remodeling and transcriptional regulation; loss of spr-5 activity can suppress the egg-laying defective (Egl) phenotype of mutations in sel-12/presenilin and derepresses expression of hop-1, which encodes the second C. elegans presenilin, by 20- to 30-fold; in binding assays and yeast two-hybrid experiments, SPR-5 interacts with SPR-1, the C. elegans ortholog of CoREST.
34	F55F8.9	F55F8.9	n/a	chrI 5,671,663	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
35	R148.2	R148.2	n/a	chrIII 3,184,321
36	end-3	F58E10.5	n/a	chrV 14,015,253	end-3 encodes a GATA zinc finger protein, paralogous to end-1, that helps specify mesoendodermal (as opposed to mesectodermal) lineages derived from the E blastomere.
37	lem-2	W01G7.5	n/a	chrII 14,064,559	C. elegans LEM-2 protein; contains similarity to Pfam domain PF03020 LEM domain contains similarity to Interpro domains IPR013142 (LEM-like region), IPR003887 (Lamino-associated polypeptide 2/emerin), IPR011015 (LEM-like fold)
38	C41D11.4	C41D11.4	n/a	chrI 4,442,876
39	F56G4.4	F56G4.4	n/a	chrI 11,377,362	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR000533 (Tropomyosin), IPR001202 (WW/Rsp5/WWP)
40	F53F8.1	F53F8.1	n/a	chrV 20,682,534	The F53F8.1 gene encodes a homolog of human WT1, which when mutated leads to Wilms tumour (OMIM:194070).
41	M03F4.4	M03F4.4	n/a	chrX 4,957,667
42	srd-50	F15A2.4	n/a	chrX 13,480,135	C. elegans SRD-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	K04G11.1	K04G11.1	n/a	chrX 14,335,998	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
44	tag-189	T04A8.12	n/a	chrIII 4,706,131	C. elegans TAG-189 protein ; contains similarity to Cricetulus griseus Post-GPI-attachment to proteins 2.; TR:Q2ABP2
45	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
46	C26E6.3	C26E6.3	n/a	chrIII 4,945,871	contains similarity to Pfam domain PF04078 Cell differentiation family, Rcd1-like contains similarity to Interpro domain IPR007216 (Cell differentiation proteins, Rcd1-like)
47	flt-1	ZK783.4	n/a	chrIII 7,653,227	flt-1 encodes a putative homolog of flectin, an extracellular matrix protein thought to provide a microenvironment of great elasticity; however, FLT-1 protein contains no similarity to other ECM components, instead mostly appearing to be made up of chromatin or DNA-binding domains; FLT-1 also contains a glutamine/asparagine-rich domain, which may mediate epigenetic regulation.
48	W08F4.10	W08F4.10	n/a	chrII 590,892	contains similarity to Interpro domain IPR000169 (Peptidase, cysteine peptidase active site)
49	F31F4.1	F31F4.1	n/a	chrV 685,113	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
50	T05A12.3	T05A12.3	n/a	chrIV 6,885,597	contains similarity to Cryptosporidium parvum Iowa II Large low complexity coiled coil protien with large repeat region.; TR:Q5CQL9