UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F09G8.3	F09G8.3	0	chrIII 8,266,869	contains similarity to Pfam domain PF00380 Ribosomal protein S9/S16 contains similarity to Interpro domains IPR000754 (Ribosomal protein S9), IPR014721 (Ribosomal protein S5 domain 2-type fold)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C52B9.4	C52B9.4	n/a	chrX 4,262,578	contains similarity to Pfam domain PF06814 Lung seven transmembrane receptor contains similarity to Interpro domains IPR009637 (Transmembrane receptor, eukaryota), IPR008983 (Tumour necrosis factor-like)
4	srx-36	T01C4.6	n/a	chrV 7,130,371	C. elegans SRX-36 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
5	dcs-1	Y113G7A.9	n/a	chrV 20,084,683	dcs-1 encodes a scavenger mRNA decapping enzyme; dcs-1 exhibits hydrolase activity in vitro, with specificity for 7meGMP in its primary nucleoside monophosphate binding site; dcs-1 is the upstream gene in an operon with fre-1, which encodes an NADPH-dependent flavin reductase; reporter fusions using dcs-1 upstream sequence direct expression throughout the life cycle in neurons and pharyngeal muscle; expression is present in dauer larvae and enhanced by heat shock.
6	F23B2.3	F23B2.3	n/a	chrIV 9,134,019	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
7	folt-1	C06H2.4	n/a	chrV 11,142,257	folt-1 encodes a folate transporter required for folate uptake; FOLT-1 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-1 transports folate in vitro; FOLT-1 activity is acid-dependent, is sodium-independent, and is inhibited by folate derivatives, sulfasalazine, or anion transport inhibitors such as 4,4''-diisothio-cyanatostilbene-2,2''-disulphonic acid (DIDS); folt-1(ok1460) and folt-1(RNAi) animals show significantly lowered folate uptake; folt-1 is expressed in several tissues, including (most strongly) pharynx and posterior intestine, as well as head, body wall, and vulva muscles, and gonad sheath cells; FOLT-1's intestinal expression diminishes with age from larvae to adults; both FOLT-1 intestinal expression and whole-animal folate uptake are lowered in folate-supplemented food media; FOLT-1 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-2 and FOLT-3; however, folt-1(ok1460) mutants are sluggish and sterile, which might instead indicate that FOLT-1 is required for locomotion and fertility.
8	Y6B3B.9	Y6B3B.9	n/a	chrI 13,743,033	contains similarity to Pfam domain PF04031 Las1-like contains similarity to Interpro domain IPR007174 (Las1-like)
9	F13A2.6	F13A2.6	n/a	chrV 4,403,625	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
10	F41E6.12	F41E6.12	n/a	chrV 8,627,981
11	mec-5	E03G2.3	n/a	chrX 15,946,401	mec-5 encodes a collagen unique in the number of Gly-X-Y repeats and in the composition of amino acids surrounding these repeats; MEC-5 is required for normal mechanosensory response to gentle touch and for the proper functioning of the touch receptor neurons; mec-5 interacts genetically with mec-4 and mec-10 which encode degenerins (ion channels) expressed in the touch neurons, mec-9, which encodes a protein containing EGF-like and Kunitz/protease inhibitor domains secreted by the touch neurons, and mec-12, which encodes an alpha-tubulin expressed in the touch neurons; these genetic interactions suggest that MEC-5 may play a role in anchoring the degenerin complex to the extracellular matrix; MEC-5 is produced and secreted by hypodermal cells.
12	ZC190.5	ZC190.5	n/a	chrV 8,672,433
13	F55C5.8	F55C5.8	n/a	chrV 12,290,267	contains similarity to Drosophila melanogaster Flybase gene name is Srp68-PA;; FLYBASE:CG5064
14	D1025.1	D1025.1	n/a	chrX 14,521,627	contains similarity to Homo sapiens Splice isoform 3 of Q9ULU4 Protein kinase C binding protein 1; ENSEMBL:ENSP00000262975
15	E02C12.6	E02C12.6	n/a	chrV 9,370,290	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
16	dnj-14	K02G10.8	n/a	chrX 4,710,717	This gene encodes a protein containing a DnaJ ('J') domain.
17	srd-72	Y45G12C.9	n/a	chrV 2,533,025	C. elegans SRD-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
18	T13F2.4	T13F2.4	n/a	chrIV 9,790,151	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IIE7
19	dct-10	Y38H6C.5	n/a	chrV 20,503,211	C. elegans DCT-10 protein; contains similarity to Pfam domains PF03732 (Retrotransposon gag protein) , PF00098 (Zinc knuckle) contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR005162 (Retrotransposon gag protein), IPR001878 (Zinc finger, CCHC-type)
20	F59B10.3	F59B10.3	n/a	chrII 10,511,687	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
21	pac-1	C04D8.1	n/a	chrIII 8,508,167	C. elegans PAC-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR001849 (Pleckstrin-like), IPR000104 (Antifreeze protein, type I), IPR011993 (Pleckstrin homology-type), IPR000198 (RhoGAP)
22	math-39	T08E11.2	n/a	chrII 1,832,929	C. elegans MATH-39 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	M163.5	M163.5	n/a	chrX 14,475,017	contains similarity to Interpro domain IPR008995 ()
24	F25G6.1	F25G6.1	n/a	chrV 8,577,457
25	F23F1.4	F23F1.4	n/a	chrII 26,912
26	glr-1	C06E1.4	n/a	chrIII 8,586,335	glr-1 encodes an AMPA (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-1 activity is required for mediating the behavioral response to light nose touch and the frequency with which animals change locomotory direction in response to sensory cues such as food; GLR-1 and GLR-2, a second AMPA-type ionotropic glutatmate receptor, can interact to form functional heteromeric channels; GLR-1 is expressed in motorneurons and interneurons, including four of the five pairs of command interneurons that are required for locomotory control; in the ventral nerve cord and nerve ring, GLR-1 localizes to perinuclear structures in cell bodies and to punctate structures that appear to be glutamatergic postsynaptic specializations; proper GLR-1 localization in the anterior ventral nerve cord of older larvae and adults requires activity of the class I PDZ protein LIN-10; GLR-1 is ubiquitinated in vivo and its abundance at postsynaptic elements, which may influence postsynaptic strength, is regulated by ubiquitination.
27	H13N06.2	H13N06.2	n/a	chrX 15,489,935	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
28	K04C1.4	K04C1.4	n/a	chrX 14,246,093	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
29	C32E8.11	C32E8.11	n/a	chrI 3,812,136	contains similarity to Pfam domains PF02617 (ATP-dependent Clp protease adaptor protein ClpS) , PF02207 (Putative zinc finger in N-recognin (UBR box)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013993 (Zinc finger, N-recognin, metazoa), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR003126 (Zinc finger, N-recognin), IPR000315 (Zinc finger, B-box), IPR003769 (Adaptor protein ClpS, core)
30	C36B1.9	C36B1.9	n/a	chrI 8,745,380	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR003604 (Zinc finger, U1-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000568 (ATPase, F0 complex, subunit A)
31	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
32	Y45F10D.6	Y45F10D.6	n/a	chrIV 13,797,043
33	clec-170	F38A1.1	n/a	chrIV 1,270,618	C. elegans CLEC-170 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
34	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
35	C01F1.2	C01F1.2	n/a	chrII 4,300,243	C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
36	srh-266	F31F4.6	n/a	chrV 665,362	C. elegans SRH-266 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	Y57G11C.31	Y57G11C.31	n/a	chrIV 14,685,186	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
38	unc-120	D1081.2	n/a	chrI 8,461,612	unc-120 encodes a member of the MADS-box family of transcription factors that is most closely related to Drosophila blistered and the vertebrate serum response factors (SRFs); UNC-120 is required for locomotion and muscle development and for formation of the normal number of muscle A and I bands; UNC-120 is also required for maintaining wild-type expression levels of the muscle components actin and myosin; UNC-120 is first expressed in the early embryo in body wall muscle precursors and later is expressed in both body wall and vulval muscles.
39	M60.6	M60.6	n/a	chrX 8,250,273
40	Y47D3B.1	Y47D3B.1	n/a	chrIII 11,385,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008166 (Protein of unknown function DUF23), IPR000276 (GPCR, rhodopsin-like)
41	Y47H9C.2	Y47H9C.2	n/a	chrI 11,842,812	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domain IPR001594 (Zinc finger, DHHC-type)
42	C05G5.1	C05G5.1	n/a	chrX 14,737,200	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
43	cdr-1	F35E8.11	n/a	chrV 15,922,065	cdr-1 encodes a member of the cadmium-inducible lysosomal family that affects susceptibility to cadmium toxicity; expressed in intestinal cells.
44	nhr-165	C47F8.2	n/a	chrI 12,332,239	C. elegans NHR-165 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	cand-1	Y102A5A.1	n/a	chrV 16,808,692	C. elegans CAND-1 protein; contains similarity to Pfam domains PF02985 (HEAT repeat) (2), PF08623 (TATA-binding protein interacting (TIP20)) contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR013932 (TATA-binding protein interacting (TIP20)), IPR016024 (Armadillo-type fold)
46	C01B10.7	C01B10.7	n/a	chrIV 6,638,773	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
47	F32B6.9	F32B6.9	n/a	chrIV 9,904,788	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
48	K01A2.3	K01A2.3	n/a	chrII 315,416
49	F54B3.2	F54B3.2	n/a	chrII 10,269,583	contains similarity to Schizosaccharomyces pombe Hypothetical protein.; TR:Q9UT52
50	T10F2.4	T10F2.4	n/a	chrIII 5,171,158	contains similarity to Pfam domains PF08606 (Prp19/Pso4-like) , PF00400 (WD domain, G-beta repeat) (6)contains similarity to Interpro domains IPR003613 (U box), IPR011046 (WD40 repeat-like), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR009053 (Prefoldin), IPR001680 (WD40 repeat), IPR013915 (Pre-mRNA-splicing factor 19), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)