UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nas-14	F09E8.6	0	chrIV 13,172,108	nas-14 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-14::GFP promoter fusion is expressed in the pharynx.
2	F21D9.4	F21D9.4	n/a	chrV 19,255,280	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
3	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	eat-2	Y48B6A.4	n/a	chrII 14,169,168	eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
5	dyb-1	F47G6.1	n/a	chrI 1,486,779	The dyb-1 gene encodes a homolog of mammalian alpha-dystrobrevin (DTNA; OMIM:601239), mutation of which can lead to left ventricular noncompaction with congenital heart defects.
6	fox-1	T07D1.4	n/a	chrX 2,448,279	fox-1 encodes an RNA-binding protein of the RNA recognition motif (RRM) superfamily of ribonucleic acid binding proteins; during C. elegans development, FOX-1 functions redundantly with other numerator elements to effect proper dosage compensation in the early embryo; in influencing dosage compensation, FOX-1 likely acts via post-transcriptional regulation of xol-1 mRNA levels; in addition to its role in dosage compensation, fox-1 activity is also required for normal male mating behavior; Western analysis and lacZ reporter constructs indicate that FOX-1 is expressed throughout the life cycle, beginning at the 18-20-cell stage of embryogenesis and continuing on through larval stages and into adult hermaphrodites and males; while early embryonic expression of fox-1 is ubiquitous, postembryonic expression is limited to a subset of head and tail neurons.
7	K09D9.3	K09D9.3	n/a	chrV 4,020,029
8	C50B8.5	C50B8.5	n/a	chrV 13,582,800	contains similarity to Candida albicans Hypothetical membrane protein.; TR:O94057
9	BE10.4	BE10.4	n/a	chrIII 12,815,049	contains similarity to Interpro domain IPR000694 (Proline-rich region)
10	lin-13	C03B8.4	n/a	chrIII 7,704,833	Gene Function : lin-13 encodes a large (2248-residue) nuclear protein with multiple zinc fingers of the C2H2 class and a LXCXE retinoblastoma protein-binding motif, that is required for survival through larval development and for negative regulation of vulval fates during postembryonic development.
11	T28D6.7	T28D6.7	n/a	chrIII 11,345,403	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
12	srd-15	C04E6.10	n/a	chrV 5,905,617	C. elegans SRD-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
13	F02D10.4	F02D10.4	n/a	chrX 13,458,404	contains similarity to Emericella nidulans Anucleate primary sterigmata protein B.; SW:APSB_EMENI
14	F10D11.5	F10D11.5	n/a	chrI 8,443,821	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
15	Y7A5A.6	Y7A5A.6	n/a	chrX 15,798,435	contains similarity to Schizosaccharomyces pombe Putative transcriptional regulatory protein, phd finger.; TR:Q9HDV4
16	F54C4.4	F54C4.4	n/a	chrIII 87,055
17	Y39E4B.6	Y39E4B.6	n/a	chrIII 13,072,610	contains similarity to Rattus norvegicus Nucleolar protein NOP5 (Nucleolar protein 5) (Nopp140 associatedsprotein).; SW:NOP5_RAT
18	C46E10.5	C46E10.5	n/a	chrII 3,712,130
19	unc-9	R12H7.1	n/a	chrX 13,214,484	unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.
20	Y56A3A.2	Y56A3A.2	n/a	chrIII 11,856,255	contains similarity to Pfam domain PF02163 Peptidase family M50 contains similarity to Interpro domains IPR008915 (Peptidase M50), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001193 (Peptidase M50, mammalian sterol-regulatory element binding protein)
21	C32H11.4	C32H11.4	n/a	chrIV 12,922,267	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
22	Y116A8C.23	Y116A8C.23	n/a	chrIV 17,054,490	contains similarity to Interpro domain IPR000694 (Proline-rich region)
23	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
24	zig-8	Y39E4B.8	n/a	chrIII 13,126,726	zig-8 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-8::gfp reporter fusion is expressed in the PVT neuron and in pharyngeal muscle.
25	Y45F10A.3	Y45F10A.3	n/a	chrIV 13,511,278	contains similarity to Mus musculus Probable arylformamidase (EC 3.5.1.9) (Kynurenine formamidase) (KF).; SW:Q8K4H1
26	ist-1	C54D1.3	n/a	chrX 7,135,879	ist-1 encodes a pleckstrin homology (PH) and phosphotyrosine binding (PTB) domain-containing insulin receptor substrate (IRS) homolog that negatively regulates lifespan and dauer development; IST-1 potentiates insulin-like signaling, although it is not absolutely required for such signaling under most conditions; in addition to acting through the AGE-1/PI3K branch of the insulin-like signaling pathway, IST-1 may also function in a parallel pathway to activate downstream protein-kinase Bs encoded by akt-1 and akt-2.
27	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
28	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
29	H35B03.1	H35B03.1	n/a	chrIV 5,727,641
30	C41G7.7	C41G7.7	n/a	chrI 9,534,916	contains similarity to Plasmodium falciparum S-antigen (Fragment).; TR:Q9GZB4
31	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
32	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
33	C32D5.7	C32D5.7	n/a	chrII 6,337,900
34	gck-2	ZC404.9	n/a	chrV 6,790,540	C. elegans GCK-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00780 (CNH domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001180 (Citron-like), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	H36L18.1	H36L18.1	n/a	chrX 12,650,135	contains similarity to Pfam domains PF00413 (Matrixin) , PF00045 (Hemopexin) (3)contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
36	srd-66	Y39A3B.4	n/a	chrIII 1,981,723	C. elegans SRD-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	F53C3.7	F53C3.7	n/a	chrII 3,895,533
38	K08B12.3	K08B12.3	n/a	chrV 6,236,378	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006355 (HAD-superfamily hydrolase, subfamily IIA, hypothetical 2), IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
39	srh-44	B0334.7	n/a	chrII 11,516,530	C. elegans SRH-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	E01G6.2	E01G6.2	n/a	chrX 12,257,730	contains similarity to Streptomyces coelicolor;Streptomyces lividans Putative secreted protein (Putative TWIN ARGININ translocationsreceptor).; TR:Q9RJ68
41	H01G02.2	H01G02.2	n/a	chrIV 11,799,864	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
42	clc-2	C01C10.1	n/a	chrX 7,432,451	clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes; clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein.
43	T15B7.8	T15B7.8	n/a	chrV 6,822,465	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
44	K11H12.4	K11H12.4	n/a	chrIV 674,988	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
45	T28D9.11	T28D9.11	n/a	chrII 6,491,500
46	flp-4	C18D1.3	n/a	chrII 10,054,913	C. elegans FLP-4 protein ;
47	unc-24	F57H12.2	n/a	chrIV 7,980,963	unc-24 encodes a protein that contains a stomatin-like domain and a lipid transfer domain; unc-24 activity is essential for normal locomotion and for wild-type sensitivity to lipid-soluble volatile anesthetics; unc-24 is genetically epistatic to unc-79 and to unc-1, which encodes an additional stomatin whose stability and localization to the nerve ring are dependent upon UNC-24; unc-24 is expressed in the touch receptor neurons as well as neurons in the ventral cord.
48	Y56A3A.6	Y56A3A.6	n/a	chrIII 11,874,979	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region), IPR002951 (Atrophin)
49	F25B3.2	F25B3.2	n/a	chrV 9,578,510	contains similarity to Lactococcus lactis Oligopeptide transport system permease protein oppC.; SW:OPPC_LACLA
50	fis-1	F41G3.4	n/a	chrII 6,755,453	C. elegans FIS-1 protein; contains similarity to Interpro domains IPR016543 (Tetratricopeptide repeat 11 Fission 1 protein), IPR011990 (Tetratricopeptide-like helical)