UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F09B9.1	F09B9.1	0	chrX 10,140,628	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
2	ncr-1	F02E8.6	n/a	chrX 4,476,155	ncr-1 encodes a large transmembrane glycoprotein with a patched-like domain that is orthologous to human NPC1 (OMIM:257220, mutated in Niemann-Pick type C disease); NCR-1 and NPC1 are eukaryotic members of the resistance-nodulation-division (RND) family of membrane permeases, and have a putative sterol-sensing domain; by homology, NCR-1 is predicted to function in intracellular cholesterol and glycolipid trafficking; in C. elegans, NCR-1 is required for growth and survival in the absence of cholesterol, newly hatched ncr-1 mutant larvae grow poorly on cholesterol-free medium and die at the L1 or L2 stage; NCR-1 is also involved in negative regulation of dauer formation, being required redundantly with NCR-2, a second C. elegans NPC1-like protein, for preventing constitutive dauer formation; dauer formation in ncr-1; ncr-2 double mutants is suppressed by mutations in daf-12, which encodes a steroid hormone receptor, and by overexpression of daf-9, which encodes a cytochrome P450, suggesting that NCR-1 and NCR-2 may function to transport a sterol precursor that is metabolized by DAF-9 to then serve as the DAF-12 ligand.
3	C31B8.8	C31B8.8	n/a	chrV 2,907,725	contains similarity to Pfam domains PF01471 (Putative peptidoglycan binding domain) , PF00413 (Matrixin) , PF00045 (Hemopexin) (2)contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin), IPR002477 (Peptidoglycan binding-like), IPR016293 (Peptidase M10A, matrix metallopeotidase)
4	Y7A9A.1	Y7A9A.1	n/a	chrIV 16,199,192	contains similarity to Pfam domain PF01019 Gamma-glutamyltranspeptidase contains similarity to Interpro domain IPR000101 (Gamma-glutamyltranspeptidase)
5	F52E1.2	F52E1.2	n/a	chrV 8,411,177	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
6	R02D5.3	R02D5.3	n/a	chrV 14,483,717	contains similarity to Arabidopsis thaliana Putative RNA-binding protein.; TR:Q9SHZ5
7	F14H12.3	F14H12.3	n/a	chrX 4,344,919	contains similarity to Pfam domain PF00090 Thrombospondin type 1 domain contains similarity to Interpro domains IPR008085 (Thrombospondin, subtype 1), IPR000884 (Thrombospondin, type I)
8	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
9	F55E10.7	F55E10.7	n/a	chrX 8,349,739	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
10	T20H4.2	T20H4.2	n/a	chrIII 7,242,074	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
11	Y41E3.6	Y41E3.6	n/a	chrIV 15,006,683	contains similarity to Bacillus halodurans Stress-and starvation-induced gene controlled by sigma-B.; TR:Q9KE40
12	lact-1	F46H5.8	n/a	chrX 7,259,241	lact-1 encodes a beta-lactamase domain-containing protein.
13	sulp-4	K12G11.1	n/a	chrV 11,877,220	sulp-4 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-4 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-4 exhibits robust transport of sulfate and more modest transport of chloride ions and oxalate; a SULP-4::GFP fusion is expressed in the apical canaliculae of the excretory cell and also in some head neurons.
14	C14C6.2	C14C6.2	n/a	chrV 563,724	contains similarity to Pfam domains PF04942 (CC domain) , PF01549 (ShK domain-like) (2)contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
15	F56H11.6	F56H11.6	n/a	chrIV 9,528,961	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
16	F38E1.3	F38E1.3	n/a	chrV 8,376,994	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
17	F33C8.4	F33C8.4	n/a	chrX 14,733,294	contains similarity to Interpro domain IPR006209 (EGF-like domain)
18	F28F5.4	F28F5.4	n/a	chrIII 6,816,698
19	Y41C4A.11	Y41C4A.11	n/a	chrIII 11,721,632	Y41C4A.11 encodes a divergent paralog of F38E11.5, the beta' (beta-prime) subunit of the coatomer (COPI) complex; unlike F38E11.5, Y41C4A.11 has no obvious function in mass RNAi assays.
20	R05D3.6	R05D3.6	n/a	chrIII 8,350,531	R05D3.6 encodes the epsilon subunit of the soluble, catalytic F1 portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); RNAi experiments indicate that loss of R05D3.6 activity has minor effects on growth rate.
21	daf-7	B0412.2	n/a	chrIII 812,789	daf-7 encodes a member of the transforming growth factor beta superfamily that affects dauer larvae formation in a TGF-beta-mediated pathway and also affects egg laying; expressed in the ASI neurons.
22	C14A4.13	C14A4.13	n/a	chrII 10,619,389	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	C50A2.2	C50A2.2	n/a	chrIV 1,173,690	contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
24	B0280.11	B0280.11	n/a	chrIII 7,137,323	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
25	tps-2	F19H8.1	n/a	chrII 14,605,629	tps-2 encodes one of two trehalose-6-phosphate synthase proteins in C. elegans, and RNAi of both enzymes leads to a more than 90% reduction decrease in trehalose levels, but does not appear to affect viability or development; the tps-2 mRNA is expressed throughout development.
26	nspc-13	F42F12.6	n/a	chrX 12,357,636	C. elegans NSPC-13 protein ;
27	Y37D8A.2	Y37D8A.2	n/a	chrIII 12,822,776	contains similarity to Pfam domain PF04916 Phospholipase B contains similarity to Interpro domains IPR007000 (Laminin A), IPR013032 (EGF-like region, conserved site)
28	clec-51	B0218.6	n/a	chrIV 8,162,862	C. elegans CLEC-51 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR003990 (Pancreatitis-associated protein), IPR001304 (C-type lectin), IPR002352 (Eosinophil major basic protein)
29	far-8	K02F3.3	n/a	chrIII 843,359	C. elegans FAR-8 protein ;
30	C33H5.16	C33H5.16	n/a	chrIV 7,802,511	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
31	ttr-46	T07C12.7	n/a	chrV 9,951,666	C. elegans TTR-46 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
32	C43G2.4	C43G2.4	n/a	chrIV 6,562,982	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
33	nas-32	T02B11.7	n/a	chrV 897,042	C. elegans NAS-32 protein; contains similarity to Pfam domains PF01549 (ShK domain-like) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site), IPR003582 (Metridin-like ShK toxin)
34	F43G9.3	F43G9.3	n/a	chrI 8,613,923	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002167 (Graves disease carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
35	C49C8.1	C49C8.1	n/a	chrIV 8,655,687	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
36	sre-1	B0495.1	n/a	chrII 7,710,540	sre-1 encodes a putative seven transmembrane chemoreceptor; an SRE-1::GFP reporter is expressed in the ADL and ASJ amphid sensory neurons.
37	srx-78	C01G10.3	n/a	chrV 15,096,226	C. elegans SRX-78 protein
38	W07B8.3	W07B8.3	n/a	chrV 1,125,705
39	lips-13	T13B5.7	n/a	chrII 1,116,848	C. elegans LIPS-13 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
40	pho-4	T16D1.2	n/a	chrII 5,237,340	C. elegans PHO-4 protein ;
41	F42G8.9	F42G8.9	n/a	chrIV 8,117,087
42	F36H2.3	F36H2.3	n/a	chrI 9,258,077	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
43	glb-13	F19H6.2	n/a	chrX 12,374,995	glb-13 encodes a globin with no obvious function in mass RNAi assays.
44	Y43F8A.3	Y43F8A.3	n/a	chrV 19,379,196	contains similarity to Pfam domain PF07859 alpha/beta hydrolase fold contains similarity to Interpro domains IPR017157 (Arylacetamide deacetylase), IPR013094 (Alpha/beta hydrolase fold-3)
45	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
46	B0457.4	B0457.4	n/a	chrII 8,911,392	contains similarity to Bacteriophage phi-C31 Gp21.; TR:Q9ZX87
47	cyp-33C6	F41B5.7	n/a	chrV 2,248,474	C. elegans CYP-33C6 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
48	srh-264	T06E6.8	n/a	chrV 15,414,724	C. elegans SRH-264 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	ubc-23	C28G1.1	n/a	chrX 8,846,276	ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells.
50	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)