UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxb-105	F08D12.8	5.999999999999999e-176	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
2	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
3	C17E4.2	C17E4.2	n/a	chrI 9,413,650	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
4	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
5	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
6	sdz-9	F08D12.10	6e-30	chrII 2,773,000	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
7	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
8	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
9	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
10	T08E11.5	T08E11.5	n/a	chrII 1,822,035
11	vet-6	F44F1.7	n/a	chrI 13,271,377	vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
12	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB
13	C28H8.1	C28H8.1	n/a	chrIII 5,926,486	C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma.
14	C02B8.2	C02B8.2	n/a	chrX 8,144,673
15	fbxb-103	F53C3.2	8e-24	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
16	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
17	W04A8.1	W04A8.1	n/a	chrI 13,837,656	W04A8.1 encodes a protein weakly similar to human microcephalin (MCPH1; OMIM:607117, mutated in primary microcephaly); while their primary sequence similarity is very subtle (only being detectable with psi-BLAST on NCBI-nr, using C. briggsae CBG13622 as a query sequence), both W04A8.1 and microcephalin has similar ordering of BRCT domains (one N-terminal, two C-terminal); W04A8.1 has no obvious function in mass RNAi screens.
18	Y116A8B.1	Y116A8B.1	n/a	chrIV 17,216,790	contains similarity to Oryza sativa P0660F12.13 protein (P0614D08.10 protein).; TR:Q94CR6
19	ZK899.6	ZK899.6	n/a	chrX 9,463,973	contains similarity to Saccharomyces cerevisiae Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function; SGD:YPL195W
20	C03C10.5	C03C10.5	n/a	chrIII 4,090,398	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IEF0
21	efn-4	F56A11.3	n/a	chrIV 563,657	efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
22	sdz-37	ZK673.10	n/a	chrII 10,465,005	C. elegans SDZ-37 protein ;
23	K08H10.9	K08H10.9	n/a	chrV 9,992,294	contains similarity to Pfam domain PF04051 Transport protein particle (TRAPP) component, Bet3 contains similarity to Interpro domain IPR007194 (Transport protein particle (TRAPP) component, Bet3)
24	JC8.4	JC8.4	n/a	chrIV 13,243,908	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
25	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
26	ndx-6	EEED8.8	n/a	chrII 5,389,360	The ndx-6 gene encodes a NUDIX hydrolase.
27	ZK563.5	ZK563.5	n/a	chrX 3,378,206	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17A46
28	F20B6.7	F20B6.7	n/a	chrX 4,207,129
29	F56B3.9	F56B3.9	n/a	chrIV 772,200
30	ZK666.1	ZK666.1	n/a	chrII 10,471,061	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T282
31	ZK1098.3	ZK1098.3	n/a	chrIII 9,535,467	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
32	btb-13	ZC204.11	n/a	chrII 1,654,256	C. elegans BTB-13 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
33	R11A5.3	R11A5.3	n/a	chrI 7,863,191	contains similarity to Mycobacterium tuberculosis DNA-binding protein HU homolog (Histone-like protein) (Hlp) (21-kDaslaminin-2-binding protein).; SW:DBH_MYCTU
34	K08H2.4	K08H2.4	n/a	chrX 13,239,283
35	R07C3.7	R07C3.7	n/a	chrII 916,765
36	R05H5.5	R05H5.5	n/a	chrII 10,200,234	contains similarity to Pfam domain PF04161 Arv1-like family contains similarity to Interpro domains IPR007290 (Arv1-like protein), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
37	phat-1	C46H11.8	n/a	chrI 5,045,010	C. elegans PHAT-1 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
38	C07B5.6	C07B5.6	n/a	chrX 9,520,189	contains similarity to Helicobacter pylori Hypothetical protein HP1327.; TR:O25885
39	pri-2	W02D9.1	n/a	chrI 12,530,247	pri-2 encodes a homolog of the DNA polymerase alpha-primase subunit C that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and for normal mitosis in the germline.
40	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
41	F55G7.2	F55G7.2	n/a	chrX 11,930,695	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
42	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
43	T28C6.3	T28C6.3	n/a	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
44	ZK666.4	ZK666.4	n/a	chrII 10,477,397	contains similarity to Oryza sativa Putative retinoblastoma-related protein 1.; TR:Q84QM3
45	F36H5.4	F36H5.4	n/a	chrII 1,762,375
46	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
47	F35G2.3	F35G2.3	n/a	chrIV 12,210,192	contains similarity to Interpro domain IPR004226 (Tubulin binding cofactor A)
48	F58E1.12	F58E1.12	n/a	chrII 1,693,958
49	F35G12.7	F35G12.7	n/a	chrIII 4,586,958	contains similarity to Pfam domain PF03091 CutA1 divalent ion tolerance protein contains similarity to Interpro domains IPR004323 (Divalent ion tolerance protein, CutA1), IPR011322 (Nitrogen regulatory PII-like, alpha/beta)
50	T05G5.4	T05G5.4	n/a	chrIII 9,749,322	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000290632