UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F08D12.4	F08D12.4	1e-128	chrII 2,778,750	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
2	ZK380.4	ZK380.4	n/a	chrX 1,652,654
3	F56H6.3	F56H6.3	n/a	chrI 12,289,861
4	grl-12	F28A12.2	n/a	chrV 8,636,381	grl-12 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
5	ztf-9	ZK287.6	n/a	chrV 9,691,558	C. elegans ZTF-9 protein; contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
6	srh-278	T09F5.8	n/a	chrV 15,171,028	C. elegans SRH-278 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	C08A9.8	C08A9.8	n/a	chrX 17,103,774	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
8	F10E7.8	F10E7.8	n/a	chrII 7,103,165	F10E7.8 encodes a FAR11-like protein that inhibits DHC-1 in vivo; F10E7.8 is orthologous to human FAM40A and FAM40B, and to budding yeast FAR11; F10E7.8(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F10E7.8 negatively regulates dynein; in early embryos, F10E7.8 is a pronuclear and nuclear protein; F10E7.8 has no obvious function in mass RNAi assays.
9	F38E1.11	F38E1.11	n/a	chrV 8,379,393
10	wrn-1	F18C5.2	n/a	chrII 6,557,068	wrn-1 encodes an ortholog of human WRN, which when mutated leads to Werner syndrome (OMIM:277700), and one of four C. elegans homologs of the RecQ DNA helicase family that includes E. coli RecQ; by homology, WRN-1 is predicted to function as a helicase, DNA-dependent ATPase, and exonuclease that plays a key role in DNA replication, recombination, and repair; RNA interference studies in C. elegans and the enhancement of many of the resulting phenotypes by ionizing radiation indicate that wrn-1 affects life span and aging and acts at a DNA damage checkpoint; the wrn-1 phenotypes such as premature aging are similar to those of Werner syndrome; immunolocalization studies indicate that WRN-1 expression is nuclear in cells at the embryonic, larval and adult stages.
11	srh-206	Y102A5C.15	n/a	chrV 16,954,279	C. elegans SRH-206 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	T10B10.8	T10B10.8	n/a	chrX 15,163,702	contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
13	srh-3	K04F1.5	n/a	chrV 1,683,835	C. elegans SRH-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001024 (Lipoxygenase, LH2)
14	srj-45	T03D3.6	n/a	chrV 2,836,005	C. elegans SRJ-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006162 (Phosphopantetheine attachment site)
15	srw-111	M01G12.4	n/a	chrI 12,124,188	C. elegans SRW-111 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	dbl-1	T25F10.2	n/a	chrV 6,759,095	dbl-1 encodes a member of the transforming growth factor beta (TGFbeta) superfamily that includes Drosophila decapentaplegic (Dpp) and the vertebrate bone morphogenetic proteins (BMPs); DBL-1 functions as a dose-dependent ligand for the SMA-6 and DAF-4 TGFbeta receptors that ultimately activate the SMA-2, -3, and -4 complex of transcription factors to regulate body length and size, as well as the patterning of male sensory rays and copulatory spicules; DBL-1 signaling upregulates sma-6 expression, suggesting that there is positive autoregulation in the DBL-1 signaling pathway; in contrast, DBL-1 negatively regulates expression of LON-1, a predicted secreted protein that is a downstream component of the body size pathway; DBL-1 is expressed primarily in neurons.
17	W09C5.1	W09C5.1	n/a	chrI 13,627,524	contains similarity to Pfam domain PF01201 Ribosomal protein S8e contains similarity to Interpro domain IPR001047 (Ribosomal protein S8e)
18	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	C54G10.1	C54G10.1	n/a	chrV 14,641,219	contains similarity to Homo sapiens similar to secreted gel-forming mucin; ENSEMBL:ENSP00000328427
20	C46A5.8	C46A5.8	n/a	chrIV 7,769,193
21	fbxa-100	F14H3.7	n/a	chrV 16,060,910	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	C30H6.9	C30H6.9	n/a	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
23	F01F1.14	F01F1.14	n/a	chrIII 5,882,603
24	str-37	C50B6.12	n/a	chrV 13,328,296	C. elegans STR-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	F55E10.1	F55E10.1	n/a	chrX 8,342,071
26	ZC477.4	ZC477.4	n/a	chrIV 7,098,647
27	C50F7.6	C50F7.6	n/a	chrIV 7,721,871	contains similarity to Homo sapiens Isoform 4 of PDZ domain-containing RING finger protein 4; ENSEMBL:ENSP00000370169
28	F29C12.3	F29C12.3	n/a	chrII 13,107,433	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
29	Y65A5A.1	Y65A5A.1	n/a	chrIV 16,399,303	contains similarity to Interpro domain IPR001092 (Basic helix-loop-helix dimerization domain bHLH)
30	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
31	F45G2.7	F45G2.7	n/a	chrIII 13,433,876	contains similarity to Oceanobacillus iheyensis Two-component response regulator involved in modulation ofsflagellar.; TR:Q8EQW9
32	K03H6.2	K03H6.2	n/a	chrIV 1,512,894	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR003659 (Plexin/semaphorin/integrin), IPR008262 (Lipase, active site), IPR016201 (Plexin-like fold)
33	B0416.3	B0416.3	n/a	chrX 9,292,441
34	snf-6	M01G5.5	n/a	chrIII 1,526,486	snf-6 encodes a member of the sodium:neurotransmitter symporter family.
35	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
36	R09H3.1	R09H3.1	n/a	chrX 1,660,650	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
37	C27F2.5	C27F2.5	n/a	chrIII 4,961,124	C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport.
38	B0238.7	B0238.7	n/a	chrV 5,261,699	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
39	F41C6.4	F41C6.4	n/a	chrX 6,874,202
40	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
41	T28C6.7	T28C6.7	n/a	chrIV 8,828,801	contains similarity to Interpro domain IPR009055 (UvrB, C-terminal UvrC-binding)
42	ZC132.8	ZC132.8	n/a	chrV 4,316,012
43	F52G3.4	F52G3.4	n/a	chrX 16,950,151
44	F21C10.6	F21C10.6	n/a	chrV 9,124,712	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
45	M03F8.5	M03F8.5	n/a	chrV 5,935,209	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
46	R05D7.1	R05D7.1	n/a	chrI 12,162,955	contains similarity to Kluyveromyces lodderae Truncated cytochrome oxidase subunit 2 (Fragment).; TR:Q7YG01
47	nhr-33	ZK455.6	n/a	chrX 11,319,573	C. elegans NHR-33 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	ZC412.8	ZC412.8	n/a	chrV 14,879,632	contains similarity to Plasmodium cynomolgi Circumsporozoite protein precursor (CS).; SW:P08675
49	R04B5.6	R04B5.6	n/a	chrV 10,086,268	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR011597 (GroES-related), IPR016040 (NAD(P)-binding), IPR002328 (Alcohol dehydrogenase, zinc-containing, conserved site)
50	nas-21	T11F9.5	n/a	chrV 11,473,207	nas-21 encodes an astacin-like metalloprotease.