UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sdz-9	F08D12.10	0	chrII 2,773,000	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
2	C17E4.2	C17E4.2	n/a	chrI 9,413,650	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
3	fbxb-103	F53C3.2	8e-18	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
4	B0304.2	B0304.2	n/a	chrII 4,524,073
5	fbxb-105	F08D12.8	1e-32	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
6	F23D12.5	F23D12.5	n/a	chrX 14,450,814	F23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.
7	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
8	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB
9	C28H8.1	C28H8.1	n/a	chrIII 5,926,486	C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma.
10	bath-9	Y49F6C.3	n/a	chrII 3,377,880	C. elegans BATH-9 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR010916 (TonB box, conserved site), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
11	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
12	F58E1.12	F58E1.12	n/a	chrII 1,693,958
13	fbxb-62	F55C9.8	n/a	chrV 19,301,505	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
14	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
15	C24H12.8	C24H12.8	n/a	chrII 422,729	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
16	fbxb-37	T16A1.8	0.000002	chrII 2,092,797	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
17	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
18	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
19	R01B10.2	R01B10.2	n/a	chrV 6,042,173
20	T28C6.3	T28C6.3	n/a	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
21	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
22	Y57A10C.1	Y57A10C.1	n/a	chrII 12,411,984	contains similarity to Macaca mulatta Thyrotropin receptor (Fragment).; TR:Q8HY53
23	F43G6.5	F43G6.5	n/a	chrII 11,815,623	contains similarity to Pfam domains PF04926 (Poly(A) polymerase predicted RNA binding domain) , PF01909 (Nucleotidyltransferase domain) , PF04928 (Poly(A) polymerase central domain) contains similarity to Interpro domains IPR007012 (Poly(A) polymerase, central region), IPR002934 (Nucleotidyltransferase), IPR007010 (Poly(A) polymerase, RNA-binding region), IPR014492 (Poly(A) polymerase), IPR011068 (Nucleotidyltransferase, class I, C-terminal-like)
24	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
25	fbxb-67	F49B2.2	0.00000009	chrI 14,297,764	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
26	sdz-37	ZK673.10	n/a	chrII 10,465,005	C. elegans SDZ-37 protein ;
27	K08H2.4	K08H2.4	n/a	chrX 13,239,283
28	fbxb-54	K05F6.7	6e-17	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
29	vet-6	F44F1.7	n/a	chrI 13,271,377	vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
30	T24C2.2	T24C2.2	n/a	chrX 14,546,208	contains similarity to Fusobacterium nucleatum Hypothetical protein FN0465.; TR:Q8RG53
31	2L52.1	2L52.1	n/a	chrII 3,265	2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
32	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
33	ced-8	F08F1.5	n/a	chrX 8,415,405	The ced-8 gene encodes a homolog of the human putative membrane transporter XK; ced-8 is required for apoptosis to occur with normal speed during embryonic development.
34	T08E11.5	T08E11.5	n/a	chrII 1,822,035
35	F31D5.6	F31D5.6	n/a	chrII 4,211,553	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
36	srab-20	T20D4.1	n/a	chrV 3,429,701	C. elegans SRAB-20 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
37	T04D3.5	T04D3.5	n/a	chrI 13,330,023
38	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
39	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
40	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
41	F55G7.2	F55G7.2	n/a	chrX 11,930,695	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
42	ndx-6	EEED8.8	n/a	chrII 5,389,360	The ndx-6 gene encodes a NUDIX hydrolase.
43	F35H10.5	F35H10.5	n/a	chrIV 8,300,920
44	Y53C12C.1	Y53C12C.1	n/a	chrII 9,827,141	Y53C12C.1 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; it has no obvious function in mass RNAi assays.
45	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
46	ZK1127.12	ZK1127.12	n/a	chrII 7,052,882
47	F10A3.1	F10A3.1	n/a	chrV 16,140,754	F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
48	M106.2	M106.2	n/a	chrII 10,847,185	contains similarity to Homo sapiens Lamin B2; ENSEMBL:ENSP00000264564
49	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
50	F35G12.7	F35G12.7	n/a	chrIII 4,586,958	contains similarity to Pfam domain PF03091 CutA1 divalent ion tolerance protein contains similarity to Interpro domains IPR004323 (Divalent ion tolerance protein, CutA1), IPR011322 (Nitrogen regulatory PII-like, alpha/beta)