UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	unc-98	F08C6.7	0	chrX 7,571,972	unc-98 encodes a protein with four C2H2 zinc fingers and several possible nuclear localization and export sequences; UNC-98 is required for normal mobility, M-line structures, and dense body (Z-line analog) structures; UNC-98 binds UNC-97/PINCH, HUM-6, and MEP-1; UNC-98 is located in M-lines, muscle cell nuclei, and perhaps dense bodies.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C24A11.2	C24A11.2	n/a	chrI 5,381,597
4	sec-24.2	ZC518.2	n/a	chrIV 12,358,176	C. elegans SEC-24.2 protein; contains similarity to Pfam domains PF04811 (Sec23/Sec24 trunk domain) , PF04815 (Sec23/Sec24 helical domain) , PF04810 (Sec23/Sec24 zinc finger) , PF00626 (Gelsolin repeat) , PF08033 (Sec23/Sec24 beta-sandwich domain) contains similarity to Interpro domains IPR006900 (Sec23/Sec24 helical region), IPR012990 (Sec23/Sec24 beta-sandwich), IPR000694 (Proline-rich region), IPR006896 (Sec23/Sec24 trunk region), IPR006895 (Zinc finger, Sec23/Sec24-type), IPR007123 (Gelsolin region)
5	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
6	Y43F4A.4	Y43F4A.4	n/a	chrIII 13,245,650	contains similarity to Homo sapiens Putative uncharacterized protein DKFZp313C0640; ENSEMBL:ENSP00000367438
7	nas-29	F58A6.4	n/a	chrII 5,140,235	C. elegans NAS-29 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
8	F35C8.2	F35C8.2	n/a	chrX 5,375,578	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
9	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
10	F13B6.1	F13B6.1	n/a	chrIV 7,457,398
11	Y41E3.6	Y41E3.6	n/a	chrIV 15,006,683	contains similarity to Bacillus halodurans Stress-and starvation-induced gene controlled by sigma-B.; TR:Q9KE40
12	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
13	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
14	F54C9.11	F54C9.11	n/a	chrII 8,584,206	contains similarity to Interpro domain IPR008126 (Outer membrane adhesion, Yersinia)
15	F17H10.1	F17H10.1	n/a	chrX 13,106,728	contains similarity to Danio rerio Protein SERAC1.; SW:Q5SNQ7
16	gon-1	F25H8.3	n/a	chrIV 9,940,393	gon-1 encodes a functional metalloprotease that defines a new sub-family of secreted proteases known as MPT (metalloprotease with thrombospondin type 1 repeats); the other two members of this family are the bovine procollagen I N-protease ( PINP ) and the murine enzyme ADAMTS-1; gon-1 is essential for hermaphrodite gonadal morphogenesis; sequence homology with other metalloproteases suggests that it functions by remodelling the extracellular matrix; GON-1 is expressed at high levels within the gonadal distal tip cell during migration.
17	plc-2	Y75B12B.6	n/a	chrV 15,195,140	C. elegans PLC-2 protein; contains similarity to Pfam domains PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes)
18	ZK228.3	ZK228.3	n/a	chrV 18,459,731	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
19	B0331.2	B0331.2	n/a	chrV 9,660,245	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
20	F14B8.6	F14B8.6	n/a	chrX 6,930,764
21	Y45F3A.8	Y45F3A.8	n/a	chrIII 10,591,217	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
22	F37B12.1	F37B12.1	n/a	chrII 9,028,078	contains similarity to Scyliorhinus canicula Homeodomain protein Otx1 (Fragment).; TR:Q90XZ0
23	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
24	his-16	ZK131.10	n/a	chrII 13,817,860	his-16 encodes an H2A histone; his-16 is contained within the histone gene cluster HIS3.
25	egl-23	Y37A1B.11	n/a	chrIV 14,007,827	egl-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; egl-23 was originally defined by gain-of-function mutations that result in defects in locomotion, egg-laying, and enteric muscle activation; loss of egl-23 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that EGL-23 may function redundantly with other TWK channels; egl-23 does not, however, interact genetically with the UNC-93 group of TWKs encoded by unc-93, sup-9, and sup-10; the EGL-23 expression pattern is not yet known.
26	T11B7.2	T11B7.2	n/a	chrIV 8,844,038	contains similarity to Homo sapiens remodeling and spacing factor 1; ENSEMBL:ENSP00000311513
27	F40A3.2	F40A3.2	n/a	chrV 7,880,134	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
28	R173.3	R173.3	n/a	chrX 7,033,107	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
29	nas-32	T02B11.7	n/a	chrV 897,042	C. elegans NAS-32 protein; contains similarity to Pfam domains PF01549 (ShK domain-like) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site), IPR003582 (Metridin-like ShK toxin)
30	apm-1	F55A12.7	n/a	chrI 5,343,455	The apm-1 gene encodes an adaptin: specifically, it encodes an ortholog of the mu1-II subunit of adaptor protein complex 1 (AP-1).
31	R07H5.9	R07H5.9	n/a	chrIV 11,208,377	contains similarity to Saccharomyces cerevisiae involved in septin organization; SGD:YCL024W
32	C25F9.6	C25F9.6	n/a	chrV 19,405,134	contains similarity to Ectromelia virus EVM128.; TR:Q8JL89
33	D1007.3	D1007.3	n/a	chrI 4,576,495
34	W03G11.3	W03G11.3	n/a	chrX 12,101,925	contains similarity to Pfam domain PF01120 Alpha-L-fucosidase contains similarity to Interpro domains IPR016286 (Alpha-L-fucosidase), IPR017853 (Glycoside hydrolase, catalytic core), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR000933 (Glycoside hydrolase, family 29 (alpha-L-fucosidase))
35	W02B12.1	W02B12.1	n/a	chrII 11,450,148	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
36	bath-46	T07H3.2	n/a	chrII 1,598,755	C. elegans BATH-46 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
37	F35D2.1	F35D2.1	n/a	chrII 7,577,252
38	sre-42	Y57A10B.4	n/a	chrII 12,385,670	C. elegans SRE-42 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR001356 (Homeobox)
39	pad-1	Y18D10A.13	n/a	chrI 12,890,677	The pad-1 gene encodes a highly conserved, but unfamiliar, protein that is required for embryonic development.
40	ZK1320.9	ZK1320.9	n/a	chrII 9,685,397	contains similarity to Pfam domain PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
41	C55A6.7	C55A6.7	n/a	chrV 11,519,888	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
42	cyp-33C9	C50H11.15	n/a	chrV 3,093,157	C. elegans CYP-33C9 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
43	Y41C4A.8	Y41C4A.8	n/a	chrIII 11,707,793	contains similarity to Aedes aegypti Hypothetical conserved protein (Putative uncharacterized protein).; TR:Q1HQM0
44	nsy-1	F59A6.1	n/a	chrII 5,026,357	nsy-1 encodes a MAP kinase kinase kinase homolog that affects chemotaxis, egg laying, and pathogen response; NSY-1 activity is activated by the calmodulin kinase UNC-43, and is required for lateral signalling that leads to asymmetric olfactory neuron fates; interacts with SEK-1, and is expressed in the intestine, hypodermis, rectal gland cells, and neurons.
45	K04F10.1	K04F10.1	n/a	chrI 6,365,571	The K04F10.1 gene encodes a homolog of SCA1, which when mutated leads to spinocerebellar ataxia 1 (OMIM:164400).
46	T05B11.1	T05B11.1	n/a	chrV 7,750,009	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
47	ttr-46	T07C12.7	n/a	chrV 9,951,666	C. elegans TTR-46 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
48	F36H2.3	F36H2.3	n/a	chrI 9,258,077	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
49	glb-13	F19H6.2	n/a	chrX 12,374,995	glb-13 encodes a globin with no obvious function in mass RNAi assays.
50	ZK892.4	ZK892.4	n/a	chrII 10,007,287	ZK892.4 is orthologous to the human gene ALPHA-METHYLACYL-CoA RACEMASE (AMACR; OMIM:604489), which when mutated leads to AMACR deficiency.