UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	gcy-12	F08B1.2	0	chrII 5,314,665	gcy-12 encodes a membrane guanylyl cyclase; a gcy-12::GFP reporter is expressed in the PHA neurons as well as in a number of head sensory neurons including AFD, AWC, and ASE; when expressed in COS-M6 cells, GCY-12 exhibits temperature-dependent guanylyl cyclase activity.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C32H11.9	C32H11.9	n/a	chrIV 12,935,630	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
4	R09E10.3	R09E10.3	n/a	chrIV 10,312,202	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
5	D2096.10	D2096.10	n/a	chrIV 8,388,092
6	Y116A8C.38	Y116A8C.38	0.000000002	chrIV 17,132,537	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
7	C49G7.1	C49G7.1	n/a	chrV 4,057,600	contains similarity to Pfam domains PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
8	C18H7.7	C18H7.7	n/a	chrIV 596,081
9	K01A6.4	K01A6.4	n/a	chrIV 11,739,659	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin)
10	tps-2	F19H8.1	n/a	chrII 14,605,629	tps-2 encodes one of two trehalose-6-phosphate synthase proteins in C. elegans, and RNAi of both enzymes leads to a more than 90% reduction decrease in trehalose levels, but does not appear to affect viability or development; the tps-2 mRNA is expressed throughout development.
11	F35C5.1	F35C5.1	n/a	chrII 12,881,287	contains similarity to Saccharomyces cerevisiae B-type regulatory subunit of protein phosphatase 2A (PP2A); SGD:YOR014W
12	M05B5.3	M05B5.3	n/a	chrI 7,187,440	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
13	Y70G10A.2	Y70G10A.2	n/a	chrIII 10,229,611	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
14	ZK1010.5	ZK1010.5	n/a	chrIII 12,985,882	contains similarity to Interpro domain IPR000694 (Proline-rich region)
15	F52F10.3	F52F10.3	n/a	chrV 1,540,095	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
16	T10E9.6	T10E9.6	n/a	chrI 6,529,637	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
17	K10C9.7	K10C9.7	n/a	chrV 1,066,687
18	tag-191	C53A5.4	n/a	chrV 14,535,355	C. elegans TAG-191 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
19	ZK930.5	ZK930.5	n/a	chrII 11,882,963	contains similarity to Methanobacterium thermoautotrophicum Phosphoserine phosphatase.; TR:O27663
20	try-7	ZC581.6	n/a	chrI 6,642,054	C. elegans TRY-7 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
21	kcc-3	K02A2.3	n/a	chrII 7,428,601	C. elegans KCC-3 protein; contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR000076 (K-Cl co-transporter), IPR004841 (Amino acid permease-associated region)
22	F01D4.3	F01D4.3	0.000002	chrIV 10,474,640	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR005819 (Histone H5), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site), IPR001984 (Peptidase S16, Lon protease)
23	C01B12.4	C01B12.4	n/a	chrII 7,948	contains similarity to Interpro domain IPR005178 (Protein of unknown function DUF300)
24	fbxa-202	T28C12.3	n/a	chrV 6,328,019	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
25	F16G10.5	F16G10.5	n/a	chrII 2,368,093
26	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
27	F16G10.2	F16G10.2	n/a	chrII 2,375,633	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
28	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5
29	Y23H5A.4	Y23H5A.4	n/a	chrI 2,618,955	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
30	Y45F10B.2	Y45F10B.2	n/a	chrIV 13,595,366	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_6700.; TR:Q98PP9
31	ZK1127.2	ZK1127.2	n/a	chrII 7,063,323	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
32	F21H7.2	F21H7.2	n/a	chrV 16,228,334	contains similarity to Homo sapiens Neurofilament heavy polypeptide; ENSEMBL:ENSP00000311997
33	F23C8.8	F23C8.8	0.002	chrI 2,431,177	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
34	C49A1.2	C49A1.2	n/a	chrI 14,210,845	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
35	R102.7	R102.7	n/a	chrIV 10,703,834
36	ncl-1	ZK112.2	n/a	chrIII 7,734,657	ncl-1 encodes a cytoplasmic B-box zinc finger protein that negatively regulates rRNA and 5S RNA transcription, nucleolus size, and body size; NCL-1 is orthologous to Drosophila BRAIN TUMOR (BRAT), and ncl-1 mutants can be rescued by brat transgenes; NCL-1 is required for the normally small size of neuronal, muscle, and hypodermal nucleoli, and is already active in 4-cell embryos; NCL-1 may be a repressor of RNA polymerase I and III transcription and an inhibitor of cell growth, based on mutant analysis; ncl-1 animals have much larger neuronal nucleoli than normal, somewhat larger muscle and hypodermal nucleoli, but essentially normal intestinal and germline nucleoli (the last of which are large even in wild-type animals); conversely, intestinal and germline cells have the lowest amounts of NCL-1 protein; ncl-1 animals are 9% larger, have 22% more protein and twice as much rRNA, and transcribe rRNA twice as much as wild-type worms; ncl-1 functions cell autonomously, and ncl-1 mutations suppress the tumorous germline phenotype of pro-1(na48) mutants.
37	ZK849.1	ZK849.1	n/a	chrI 14,184,199	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
38	ZC581.2	ZC581.2	n/a	chrI 6,656,611	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	K03H1.9	K03H1.9	n/a	chrIII 9,941,014	contains similarity to Homo sapiens DAN15 protein; TR:Q99491
40	AC7.3	AC7.3	n/a	chrIV 5,112,248
41	C08G5.2	C08G5.2	n/a	chrII 740,228
42	spe-15	F47G6.4	n/a	chrI 1,456,004	spe-15 encodes an unconventional myosin, and is homologous to both Drosophila and mouse myosin VI; spe-15 was identified in screens for mutants that have defective spermatogenesis; spe-15 is required during the terminal stages of spermatogenesis for the asymmetric partitioning of organelles like the mitochondria and for the proper partitioning of specialized structures called the fibrous-body membranous organelles into the spermatid; mutant spe-15 spermatids contain actin filaments in contrast to wild-type which lack them; spe-15 is also required for the proper morphology and activation of the spermatid; the human gene MYOSIN VI (MYO6; OMIM:600970), when mutated leads to disease that affects hearing.
43	rpl-42	C09H10.1	n/a	chrII 11,093,225	C. elegans RPL-42 protein ;
44	ugt-43	F01D4.1	n/a	chrIV 10,466,113	C. elegans UGT-43 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
45	Y24D9B.1	Y24D9B.1	n/a	chrIV 4,319,658	contains similarity to Interpro domain IPR001469 (ATPase, F1 complex, delta/epsilon subunit)
46	T05C12.9	T05C12.9	n/a	chrII 8,192,426	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF02149 (Kinase associated domain 1) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001772 (Kinase-associated KA1), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
47	F37E3.3	F37E3.3	n/a	chrI 6,430,598	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
48	C32D5.4	C32D5.4	n/a	chrII 6,322,171
49	C27B7.6	C27B7.6	n/a	chrIV 8,904,670	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
50	C44F1.2	C44F1.2	n/a	chrIII 3,769,375	contains similarity to Pfam domains PF01342 (SAND domain) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR010919 (SAND-like), IPR000770 (SAND)