UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sgn-1	F07H5.2	0	chrII 8,782,783	C. elegans SGN-1 protein; contains similarity to Pfam domain PF04790 Sarcoglycan complex subunit protein contains similarity to Interpro domain IPR006875 (Sarcoglycan complex subunit protein)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	clec-151	F10F2.7	n/a	chrIII 4,629,753	C. elegans CLEC-151 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	tag-278	C02F12.7	n/a	chrX 3,686,384	C. elegans TAG-278 protein; contains similarity to Interpro domain IPR000533 (Tropomyosin)
6	cwn-2	W01B6.1	n/a	chrIV 10,069,006	cwn-2 encodes a member of the WNT family; expressed at highest levels in embryos and expression declines and is almost absent by the third larval stage.
7	hum-7	F56A6.2	n/a	chrI 596,704	hum-7 encodes a class IX unconventional myosin heavy chain that contains a myosin motor domain in the head region and zinc-finger and rhoGAP (rho GTPase activating protein) domains in the tail region; HUM-7 is required during embryogenesis for cytokinesis and normal cytoplasmic rearrangements, and by homology, may function in organization of the actin cytoskeleton; the precise expression and localization patterns of HUM-7 are not yet known.
8	T01D3.1	T01D3.1	n/a	chrV 13,691,269	contains similarity to Pfam domain PF00008 (EGF-like domain)
9	ZC328.2	ZC328.2	n/a	chrI 6,389,348	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
10	T12E12.6	T12E12.6	n/a	chrIV 5,570,564	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
11	E04F6.4	E04F6.4	n/a	chrII 7,190,903	contains similarity to Pfam domains PF08371 (Phospholipase D/viral envelope) , PF00614 (Phospholipase D Active site motif) (2)contains similarity to Interpro domains IPR013582 (Phospholipase D/viral envelope), IPR001736 (Phospholipase D/Transphosphatidylase)
12	K12H4.4	K12H4.4	n/a	chrIII 8,045,336	contains similarity to Pfam domain PF04573 Signal peptidase subunit contains similarity to Interpro domain IPR007653 (Signal peptidase 22 kDa subunit)
13	F38B6.1	F38B6.1	n/a	chrX 6,700,523
14	F38H4.3	F38H4.3	n/a	chrIV 11,845,293	contains similarity to Interpro domain IPR000694 (Proline-rich region)
15	aha-1	C25A1.11	n/a	chrI 10,195,452	aha-1 encodes an ortholog of human aryl-hydrocarbon receptor nuclear translocator; interacts with AHR-1 and HIF-1 in vitro, requires HIF-1 for proper localization, and is expressed ubiquitously.
16	F16G10.11	F16G10.11	n/a	chrII 2,392,784	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
17	del-1	E02H4.1	n/a	chrX 14,274,420	del-1 encodes an ion channel protein of the DEG/ENaC (degenerin/epithelial Na+ channel) family; like other members of the degenerin family, DEL-1 is predicted to function as a sensory mechanotransduction channel, however detailed analysis of the DEL-1 mutant phenotype has not yet been reported; DEL-1 is expressed postembryonically in the VA and VB motor neurons and in the FLP sensory neurons; the DEL-1 expression pattern overlaps that of UNC-8, an additional C. elegans degenerin involved in movement control, with which DEL-1 may coassemble to form mechanically activated cation channels.
18	btb-1	F40G9.4	n/a	chrIII 186,286	C. elegans BTB-1 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
19	F10D7.4	F10D7.4	n/a	chrX 17,380,140
20	C31H2.4	C31H2.4	n/a	chrX 5,157,381	C31H2.4 encodes a possible 4-hydroxyphenylpyruvate dioxygenase, orthologous to human HPDL/GLOXD1, and paralogous to HPD-1 and human HPD (OMIM:609695, mutated in tyrosinemia type III); C31H2.4 has no obvious function in mass RNAi experiments.
21	F25F6.1	F25F6.1	n/a	chrX 4,445,262
22	C17E4.11	C17E4.11	n/a	chrI 9,420,385	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
23	T04C9.3	T04C9.3	n/a	chrIII 5,985,695
24	osm-9	B0212.5	n/a	chrIV 3,554,256	The osm-9 gene encodes a capsaicin receptor homolog involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts.
25	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
26	daf-14	F01G10.8	n/a	chrIV 10,254,701	daf-14 encodes a Smad-related protein that is unusual in that while its C-terminus is well-conserved with Smad proteins, it lacks the N-terminal DNA binding domain found in all other known Smads; DAF-14 is predicted to function as a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and negatively regulates dauer formation; as reduction of daf-14 function enhances the dauer constitutive phenotype of daf-8 mutants, and overexpression of daf-14 can rescue daf-8 mutant animals, it is likely that the DAF-14 and DAF-8 Smad proteins function in parallel to control dauer formation; further genetic analyses suggest that DAF-14 and DAF-8 function to antagonize the activities of the DAF-3 Smad and DAF-5 Sno/Ski oncoprotein, which are required for dauer formation; a DAF-14::GFP reporter is expressed in a dynamic pattern in tissues, such as the hypodermis, intestine, and pharynx, that are remodeled during dauer development.
27	K10H10.1	K10H10.1	n/a	chrII 14,491,241	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
28	F21F8.6	F21F8.6	n/a	chrV 8,266,564
29	nhr-54	F36D3.2	n/a	chrV 16,504,904	C. elegans NHR-54 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	C52E4.5	C52E4.5	n/a	chrV 11,984,169	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
31	nhr-207	R07B7.14	n/a	chrV 12,097,016	C. elegans NHR-207 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR001728 (Thyroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	M01G4.1	M01G4.1	n/a	chrIII 6,665,107
33	rhgf-1	F13E6.6	n/a	chrX 10,704,787	rhgf-1 encodes an RGS RhoGEF (Regulator of G-protein Signaling Rho Guanine Nucleotide Exchange Factor); RHGF-1 functions within cholingergic motor neurons in one of four G-protein-mediated signaling pathways that control locomotion via regulation of acetylcholine (ACh) release at neuromuscular junctions; in regulating ACh release, RHGF-1 functions downstream of the C. elegans Galpha12 ortholog, GPA-12, and upstream of the Rho GTPase ortholog, RHO-1; additionally, rhgf-1 activity is required for normal mechanosensory behavior, egg laying, and embryonic development; an rhgf-1 reporter fusion is expressed in ventral cord motor neurons as well as several head neurons.
34	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
35	Y47D3B.1	Y47D3B.1	n/a	chrIII 11,385,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008166 (Protein of unknown function DUF23), IPR000276 (GPCR, rhodopsin-like)
36	R07B1.5	R07B1.5	n/a	chrX 9,865,660	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
37	ceh-31	C33D12.1	n/a	chrX 3,069,626	ceh-31 encodes a protein containing a homeobox domain.
38	F07C6.3	F07C6.3	n/a	chrIV 12,789,701	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
39	inft-1	F58B6.2	n/a	chrIII 1,107,561	C. elegans INFT-1 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR003104 (Actin-binding FH2 and DRF autoregulatory)
40	F19C7.4	F19C7.4	n/a	chrIV 4,604,373	contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
41	slt-1	F40E10.4	n/a	chrX 14,678,771	slt-1 encodes the sole C. elegans homolog of Drosophila Split, a secreted extracellular protein containing leucine-rich and EGF-like repeats that functions as a ligand for the Robo receptor; during C. elegans larval development, slt-1 acts via the SAX-3/Robo receptor, and in parallel with UNC-6/Netrin, to direct ventral axon guidance and guidance at the midline; during embryonic development, slt-1 also functions to regulate anterior-posterior migrations of the CAN neurons; slt-1::gfp reporters are initially expressed at high levels in the anterior part of the embryo, with more moderate levels seen in dorsal tail muscles and lower levels seen in cells in the center of the body; in L1 larvae, slt-1::gfp is expressed in both dorsal and ventral muscles, with higher levels seen in dorsal muscle cells; slt-1::gfp is also expressed in a number of additional cells including some neurons, pharyngeal cells, and the anal sphincter muscle.
42	rpm-1	C01B7.6	n/a	chrV 8,812,661	rpm-1 encodes an E3 ubiquitin ligase that contains an N-terminal RCC1 (regulator of chromosome condensation)-like guanine nucleotide exchange factor (GEF) domain and that is orthologous to Drosophila highwire and murine Phr1; RPM-1 functions autonomously within several different types of neurons to regulate presynaptic differentiation; in regulating axon termination, RPM-1 acts through the GLO-4 guanine nucleotide exchange factor that positively regulates vesicular trafficking through GLO-1/Rab; in regulating synaptogenesis, RPM-1 functions as part of an SCF-like ubiquitin ligase complex that negatively regulates signaling through the DLK-1 MAP kinase cascade; RPM-1 is expressed in most, if not all, neurons from the comma stage of embryogenesis through adulthood; RPM-1 expression is also seen in the pharynx, coelomocytes, and distal tip cells; in neurons, RPM-1 localizes to presynaptic terminals.
43	T03G11.5	T03G11.5	n/a	chrX 5,168,923
44	rpy-1	C18H9.7	n/a	chrII 6,703,848	rpy-1 is orthologous to the human gene 43KDA ACETYLCHOLINE RECEPTOR-ASSOCIATED PROTEIN (RAPSN; OMIM:601592), which when mutated leads to congenital myasthenic syndrome.
45	srd-8	B0547.4	n/a	chrIV 5,644,418	C. elegans SRD-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
47	F53B1.8	F53B1.8	n/a	chrX 2,126,824	contains similarity to Interpro domain IPR001441 (Di-trans-poly-cis-decaprenylcistransferase)
48	srw-108	R11G11.5	n/a	chrV 528,386	C. elegans SRW-108 protein ;
49	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
50	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)