UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F07G11.9	F07G11.9	0	chrV 7,317,554	contains similarity to Pfam domains PF01476 (LysM domain) (12), PF05938 (Plant self-incompatibility protein S1) , PF00704 (Glycosyl hydrolases family 18) contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR010264 (Plant self-incompatibility S1), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR001579 (Glycoside hydrolase, chitinase active site), IPR002482 (Peptidoglycan-binding LysM), IPR001002 (Chitin-binding, type 1)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	Y20C6A.1	Y20C6A.1	n/a	chrV 17,374,108	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
4	T22F7.4	T22F7.4	n/a	chrIII 526,147
5	srj-24	C05E4.11	n/a	chrV 737,838	C. elegans SRJ-24 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
6	C13A10.1	C13A10.1	n/a	chrII 1,353,185
7	ttr-54	T14G10.4	n/a	chrIV 10,156,441	C. elegans TTR-54 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
8	C54F6.4	C54F6.4	n/a	chrV 7,530,843	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
9	clec-15	T07D10.4	n/a	chrI 12,631,859	C. elegans CLEC-15 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	F26A3.1	F26A3.1	n/a	chrI 7,641,050	contains similarity to Interpro domain IPR008262 (Lipase, active site)
11	C08F11.3	C08F11.3	n/a	chrIV 13,620,866	contains similarity to Homo sapiens HOR5'Beta8; ENSEMBL:ENSP00000332473
12	ocr-3	T10B10.7	n/a	chrX 15,171,101	ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types.
13	Y40H7A.11	Y40H7A.11	n/a	chrIV 15,219,977	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
14	lov-1	ZK945.9	n/a	chrII 10,115,543	lov-1 encodes an ortholog of human PKD1 (OMIM:601313; mutated in autosomal dominant polycystic kidney disease) that is expressed in the ciliated sensory endings of three types of male-specific neurons and that is required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location; LOV-1 acts with PKD-2; EGL-44 and EGL-46 regulate cell-specific expression of lov-1 and pkd-2 to specify the behavioral function of the HOB neuron; in vitro, LOV-1 interacts, via its conserved PLAT domain, with the N-terminus of ATP-2, the beta subunit of ATP synthase that also localizes to cilia, suggesting that ATP synthase may play a role in C. elegans polycystin signaling.
15	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
16	Y2H9A.4	Y2H9A.4	n/a	chrV 13,447,397	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR007883 (Protein of unknown function DUF713), IPR005398 (Tubby, N-terminal)
17	col-85	T21B4.2	n/a	chrII 12,494,362	C. elegans COL-85 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
18	cyp-13A7	T10B9.10	n/a	chrII 9,804,455	cyp-13A7 encodes a homolog of cytochrome P450 proteins; these proteins are membrane proteins with a heme prosthetic group that catalyse the synthesis of steroid hormones (and bile salts), and also detoxify foreign substances (xenobiotic compounds).
19	K08H2.7	K08H2.7	n/a	chrX 13,247,766	contains similarity to Synechocystis sp Probable glycogen synthase 2 (EC 2.4.1.21) (Starch [bacterialsglycogen] synthase 2).; SW:GLG2_SYNY3
20	C54A12.2	C54A12.2	n/a	chrII 5,254,604	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
21	T23G7.3	T23G7.3	n/a	chrII 9,166,799	contains similarity to Pfam domain PF01585 G-patch domain contains similarity to Interpro domain IPR000467 (D111/G-patch)
22	fbxa-164	C08E3.7	n/a	chrII 1,613,450	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
23	srab-17	T11A5.2	n/a	chrV 9,867,491	C. elegans SRAB-17 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
24	K07A9.3	K07A9.3	n/a	chrIV 1,835,383	contains similarity to Interpro domain IPR001736 (Phospholipase D/Transphosphatidylase)
25	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
26	DH11.2	DH11.2	n/a	chrII 8,013,966	contains similarity to Pfam domain PF00646 (F-box domain)
27	btb-21	F47C10.2	n/a	chrV 3,850,930	C. elegans BTB-21 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
28	srg-15	C34C6.1	n/a	chrII 8,709,673	C. elegans SRG-15 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
29	grl-3	K03B8.7	n/a	chrV 11,411,850	grl-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-3 is expressed in intestine, larval renal gland cells, and larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
30	F19F10.3	F19F10.3	n/a	chrV 7,552,413
31	Y7A5A.9	Y7A5A.9	n/a	chrX 15,828,129	contains similarity to Cyprinus carpio Nucleolin.; TR:Q804J2
32	F58E6.4	F58E6.4	n/a	chrV 9,750,160	contains similarity to Homo sapiens Protein PRO1073/PRO2853; ENSEMBL:ENSP00000332769
33	Y106G6D.6	Y106G6D.6	n/a	chrI 10,120,080	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
34	fbxb-70	ZK909.5	n/a	chrI 14,956,357	C. elegans FBXB-70 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
35	C25G4.2	C25G4.2	n/a	chrIV 12,443,605	contains similarity to Pfam domain PF03959 Serine hydrolase (FSH1) contains similarity to Interpro domain IPR005645 (Protein of unknown function DUF341)
36	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
37	flp-10	T06C10.4	n/a	chrIV 7,869,261	flp-10 encodes a FMRFamide-related neuropeptide; in males, flp-10 activity is required for a sensory transduction pathway that negatively regulates the frequency of certain substeps of turning behavior during mating; a flp-10::gfp reporter is expressed in a number of neurons including AIM, ASI, AUA, BAG, BDU, DVB, PQR, PVR, and URX, and in the vulD cells.
38	D1022.5	D1022.5	n/a	chrII 7,458,058
39	F41G4.8	F41G4.8	n/a	chrX 16,844,106
40	srw-120	K12D9.5	n/a	chrV 2,995,551	C. elegans SRW-120 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
41	C02F12.5	C02F12.5	n/a	chrX 3,671,203	C02F12.5 encodes a putatively secreted protein with a Kunitz/bovine pancreatic trypsin inhibitor domain; C02F12.5 has no obvious function in mass RNAi assays.
42	ttr-37	F21E9.3	n/a	chrX 1,336,135	C. elegans TTR-37 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
43	skr-5	F47H4.10	n/a	chrV 17,348,283	The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
44	F26D11.2	F26D11.2	n/a	chrV 7,960,124
45	C18D4.4	C18D4.4	n/a	chrV 17,530,973	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
46	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
47	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
48	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
49	srbc-20	C45H4.11	n/a	chrV 2,147,858	C. elegans SRBC-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	str-88	R08H2.2	n/a	chrV 15,383,115	C. elegans STR-88 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)