UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F02C12.1	F02C12.1	0	chrX 13,404,175	contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
2	F49H6.3	F49H6.3	n/a	chrV 17,015,023	contains similarity to Pfam domain PF06653 Protein of unknown function (DUF1164) contains similarity to Interpro domain IPR009545 (Protein of unknown function DUF1164)
3	D2092.6	D2092.6	n/a	chrI 6,597,924	contains similarity to Homo sapiens Ubiquitin carboxyl-terminal hydrolase 8; ENSEMBL:ENSP00000302239
4	C02G6.1	C02G6.1	n/a	chrV 5,878,092	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
5	dbr-1	C55B7.8	n/a	chrI 6,491,723	dbr-1 encodes a homolog of the RNA lariat-debranching enzyme; DBR-1 is predicted to function in RNA processing by hydrolyzing the 2'-5' phosphodiester bond at the branchpoint of excised lariat intron RNA, thus converting the introns into linear molecules that can subsequently be degraded by exonucleases; in C. elegans, DBR-1 activity is required for embryonic and germline development, as well as for normal rates of postembryonic growth; overexpression of C. elegans DBR-1 in Saccharomyces cerevisiae can complement the RNA processing defects of a dbr1 null mutant strain, restoring debranching activity and intron degradation to near wild-type levels.
6	C34H4.2	C34H4.2	n/a	chrIV 1,554,675	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
7	ZC116.3	ZC116.3	n/a	chrV 12,620,623	ZC116.3 is orthologous to the human gene CUBILIN (CUBN; OMIM:602997), which when mutated leads to hereditary megaloblastic anaemia 1 (OMIM:261100).
8	T08B2.11	T08B2.11	n/a	chrI 6,222,182	contains similarity to Homo sapiens Transcription initiation factor TFIID subunit 3; ENSEMBL:ENSP00000340271
9	nduf-2.2	T26A5.3	n/a	chrIII 6,466,129	T26A5.3 encodes a predicted mitochondrial protein whose mature sequence has near-identity (95%) to GAS-1; T26A5.3 transcription is detectable by RT-PCR, but not visible by promoter-GFP fusion; however, a transgene containing a fusion of the gas-1 promoter to the T26A5.3 protein-coding sequence is able to fully rescue gas-1 mutants, indicating that T26A5.3 encodes a fully functional mitochondrial 49 kDa subunit that may rescue gas-1(fc21) mutants from lethality; mutants homozygous for a T26A5.3 deletion have normal anesthetic sensitivity and normal sensitivity to oxygen (unlike gas-1 mutants) but a shortened lifespan at normal laboratory oxygen levels (20%); animals doubly mutant for gas-1 and T26A5.3 have maternal-effect lethality, but sterile surviving parents are abnormally long-lived (2.7 times longer than wild-type and 4.2 times longer than gas-1 mutants); double mutants remain hypersensitive to oxygen.
10	F41E6.11	F41E6.11	n/a	chrV 8,620,645	contains similarity to Interpro domains IPR003267 (Small proline-rich), IPR000694 (Proline-rich region), IPR000480 (Glutelin)
11	clec-206	F59A7.1	n/a	chrV 2,002,373	C. elegans CLEC-206 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	C25G4.10	C25G4.10	n/a	chrIV 12,472,778	contains similarity to Pfam domains PF00047 (Immunoglobulin domain) , PF01682 (DB module) (3), PF07679 (Immunoglobulin I-set domain) , PF00041 (Fibronectin type III domain) (4)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR013098 (Immunoglobulin I-set), IPR013783 (Immunoglobulin-like fold), IPR002602 (Protein of unknown function DB), IPR007110 (Immunoglobulin-like), IPR006150 (Cysteine-rich repeat), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
13	H34I24.2	H34I24.2	n/a	chrIII 2,843,610	contains similarity to Homo sapiens Mucin-7 precursor; ENSEMBL:ENSP00000302021
14	C15C8.7	C15C8.7	n/a	chrV 12,744,584	contains similarity to Rhizobium loti Hypothetical protein mll2265.; TR:Q98IT0
15	lbp-8	T22G5.6	n/a	chrV 13,891,011	lpb-8 belongs to a family of small intracellular fatty acid binding proteins (FABPs) that includes As-p18, found in the parasitic nematode Ascaris suum; lpb-8 shares 55% identity with bovine heart FABP but only 25% identity with As-p18 and lacks a secretory signal
16	H04D03.1	H04D03.1	n/a	chrIII 10,437,086	contains similarity to Saccharomyces cerevisiae Global transcription activator that acts in complex with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators; involved in the regulation of expression of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; SGD:YPL016W
17	sre-50	C50E10.11	n/a	chrII 12,304,243	C. elegans SRE-50 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
18	W07E11.1	W07E11.1	n/a	chrX 10,093,967	contains similarity to Pfam domains PF04898 (Glutamate synthase central domain) , PF01645 (Conserved region in glutamate synthase) , PF01266 (FAD dependent oxidoreductase) , PF00310 (Glutamine amidotransferases class-II) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) , PF01493 (GXGXG motif) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000583 (Glutamine amidotransferase, class-II), IPR013785 (Aldolase-type TIM barrel), IPR006076 (FAD dependent oxidoreductase), IPR006005 (Glutamate synthase, NADH/NADPH, small subunit 1), IPR000759 (Adrenodoxin reductase), IPR006982 (Glutamate synthase, central-N), IPR002932 (Glutamate synthase, central-C), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR002489 (Glutamate synthase, alpha subunit, C-terminal), IPR012285 (Fumarate reductase, C-terminal), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR012220 (Glutamate synthase, eukaryotic), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
19	clec-185	C25G4.1	n/a	chrIV 12,440,827	C. elegans CLEC-185 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	M28.8	M28.8	n/a	chrII 10,630,658	contains similarity to Interpro domain IPR000583 (Glutamine amidotransferase, class-II)
21	T14B4.1	T14B4.1	n/a	chrII 6,739,132
22	mig-17	F57B7.4	n/a	chrV 11,447,925	mig-17 encodes a secreted metalloprotease that is a member of the ADAM (A Disintegrin And Metalloprotease) protein family; MIG-17 activity is required for proper migration of gonadal leader cells, namely the hermaphrodite distal tip cells (DTCs) and the male linker cell (MLC); a MIG-17::GFP translational fusion protein is first detected in late embryos with expression continuing through adulthood; expression is initially seen on the pseudocoelomic face of body wall muscles and then on the surface of the gonad, when the DTCs migrate on the lateral hypodermis towards the dorsal muscles; proper MIG-17 localization and glycosylation requires activity of MIG-23, a membrane-bound nucleoside diphosphatase, as well as activity of COGC-3 and COGC-1, two members of the conserved oligomeric Golgi complex; expression studies with MIG-17 deletion derivatives indicate that MIG-17 is expressed by the body wall muscles and then localizes to the DTCs where its activity is sufficient for guiding DTC migration.
23	ech-1	C29F3.1	n/a	chrV 15,359,193	ech-1 encodes an enoyl-CoA hydratase; loss of ech-1 activity via RNAi results in reduced body fat, consistent with ECH-1's predicted role in fatty acid metabolism; expression of ech-1 mRNA is positively regulated by the NHR-49 nuclear receptor.
24	sec-8	Y106G6H.7	n/a	chrI 10,449,365	The sec-8 gene encodes an ortholog of SEC8 in S. cerevisiae, a component of the exocyst complex required genetically for endocytosis, for normal cellular morphology in the intestine, and for growth at normal rates during development.
25	C04F1.1	C04F1.1	n/a	chrI 5,727,848	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
26	C06A1.2	C06A1.2	n/a	chrII 10,570,302	contains similarity to Mus musculus Olfactory receptor MOR111-5 (Olfactory receptorsGA_x6K02T2PULF-11116958-11117896).; TR:Q8VFH8
27	T07A9.10	T07A9.10	n/a	chrIV 391,835	contains similarity to Pfam domain PF00995 Sec1 family contains similarity to Interpro domain IPR001619 (Sec1-like protein)
28	T05C12.4	T05C12.4	n/a	chrII 8,178,909	contains similarity to Interpro domain IPR003566 (T-cell surface glycoprotein CD5)
29	F59B2.8	F59B2.8	n/a	chrIII 9,008,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	F18H3.4	F18H3.4	n/a	chrX 13,530,481	contains similarity to Mus musculus GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).; SW:Q8VD04
31	F17A9.5	F17A9.5	n/a	chrV 6,112,116	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
32	C45G9.1	C45G9.1	n/a	chrIII 5,075,294	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
33	prx-11	C47B2.8	n/a	chrI 12,971,925	C. elegans PRX-11 protein ; contains similarity to Homo sapiens Isoform 1 of Peroxisomal membrane protein 11C; ENSEMBL:ENSP00000221480
34	F46G10.4	F46G10.4	n/a	chrX 13,335,352	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
35	F49E11.2	F49E11.2	n/a	chrIV 13,037,470	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
36	D2096.11	D2096.11	n/a	chrIV 8,390,987	contains similarity to Pfam domains PF00307 (Calponin homology (CH) domain) (2), PF02187 (Growth-Arrest-Specific Protein 2 Domain) contains similarity to Interpro domains IPR003108 (Growth-arrest-specific protein 2), IPR002017 (Spectrin repeat), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding)
37	T07D10.3	T07D10.3	n/a	chrI 12,627,858	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
38	T20F7.3	T20F7.3	n/a	chrX 16,860,808	contains similarity to Pfam domain PF03770 Inositol polyphosphate kinase contains similarity to Interpro domain IPR005522 (Inositol polyphosphate kinase)
39	6R55.2	6R55.2	n/a	chrX 17,713,765
40	C01G6.5	C01G6.5	n/a	chrII 9,277,455	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR005819 (Histone H5), IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000253 (Forkhead-associated), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
41	lin-23	K10B2.1	n/a	chrII 6,372,870	lin-23 encodes an F-box- and WD-repeat-containing protein orthologous to Saccharomyces cerevisiae MET30 and human beta TRCP (OMIM:603482), both components of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; LIN-23 negatively regulates postembryonic cell divsions in all tissue types, and specifically, has been shown to function cell autonomously in the vulva to negatively regulate cell cycle progression and allow for cell cycle exit; LIN-23 also functions cell autonomously in some neurons to regulate neurite outgrowth; LIN-23 expression is first detected broadly during gastrulation, with expression continuing postembryonically in body wall and enteric muscle, hypodermal cells, and many but not all neurons; LIN-23 localizes to the cytoplasm.
42	rle-1	M142.6	n/a	chrIII 10,941,254	C. elegans RLE-1 protein; contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
43	H25P06.1	H25P06.1	n/a	chrI 11,317,448	contains similarity to Pfam domains PF00349 (Hexokinase) , PF03727 (Hexokinase) contains similarity to Interpro domain IPR001312 (Hexokinase)
44	F49F1.8	F49F1.8	n/a	chrIV 4,132,560	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
45	F01D5.2	F01D5.2	n/a	chrII 13,998,627	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR000480 (Glutelin), IPR003582 (Metridin-like ShK toxin)
46	try-10	F15B9.5	n/a	chrV 13,011,526	C. elegans TRY-10 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
47	E01G4.6	E01G4.6	n/a	chrII 13,483,996	contains similarity to Caenorhabditis remanei P17 (Fragment).; TR:A0MIX2
48	cua-1	Y76A2A.2	n/a	chrIII 13,447,397	The cua-1 gene encodes a putative E1-E2 ATPase orthologous to the human gene KIAA1347 (ATP7A; OMIM:604384), which when mutated leads to Hailey-Hailey disease.
49	F22E12.1	F22E12.1	n/a	chrV 10,455,572	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR000694 (Proline-rich region)
50	nas-36	C26C6.3	n/a	chrI 7,529,499	nas-36 encodes an astacin-like protease; nas-36 activity is required for molting; a nas-36::gfp reporter is expressed in hypodermal cells.